3WS5

N288Q-N321Q mutant BETA-LACTAMASE DERIVED FROM CHROMOHALOBACTER SP.560 (Condition-2B)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0008800	molecular_function	beta-lactamase activity
A	0016787	molecular_function	hydrolase activity
A	0017001	biological_process	antibiotic catabolic process
A	0030288	cellular_component	outer membrane-bounded periplasmic space
A	0046677	biological_process	response to antibiotic
A	0046872	molecular_function	metal ion binding
B	0008800	molecular_function	beta-lactamase activity
B	0016787	molecular_function	hydrolase activity
B	0017001	biological_process	antibiotic catabolic process
B	0030288	cellular_component	outer membrane-bounded periplasmic space
B	0046677	biological_process	response to antibiotic
B	0046872	molecular_function	metal ion binding
C	0008800	molecular_function	beta-lactamase activity
C	0016787	molecular_function	hydrolase activity
C	0017001	biological_process	antibiotic catabolic process
C	0030288	cellular_component	outer membrane-bounded periplasmic space
C	0046677	biological_process	response to antibiotic
C	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SR A 401

Chain	Residue
A	ASP219
A	ASP220
A	HOH539

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site_id	AC2
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CL A 402

Chain	Residue
A	VAL122

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site_id	AC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CA B 401

Chain	Residue
B	ASP291
B	GLU295
B	GLU352

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site_id	AC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CL B 402

Chain	Residue
B	VAL122
B	ASN153

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site_id	AC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CL C 401

Chain	Residue
C	PHE121
C	VAL122
C	ASN153

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Functional Information from PROSITE/UniProt

site_id	PS00336
Number of Residues	8
Details	BETA_LACTAMASE_C Beta-lactamase class-C active site. FEIGSLSK

Chain	Residue	Details
A	PHE61-LYS68

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