3WRN
Minute virus of mice non-structural protein-1N-terminal nuclease domain reveals a unique Zn2+ coordination in the active site pocket and shows a novel mode of DNA recognition at the origin of replication
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE NA A 301 |
| Chain | Residue |
| A | ASP91 |
| A | VAL116 |
| A | SER230 |
| A | SER231 |
| A | HOH411 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE NA A 302 |
| Chain | Residue |
| A | LYS49 |
| A | GLU50 |
| A | LEU51 |
| A | HOH401 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ZN A 303 |
| Chain | Residue |
| A | GLU119 |
| A | HIS127 |
| A | HIS129 |
| A | HOH434 |
| A | HOH549 |
| A | HOH553 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | ACT_SITE: For nuclease activity => ECO:0000255|PROSITE-ProRule:PRU01366, ECO:0000269|PubMed:25528417 |
| Chain | Residue | Details |
| A | TYR210 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU01366, ECO:0000269|PubMed:25528417 |
| Chain | Residue | Details |
| A | GLU119 | |
| A | HIS127 | |
| A | HIS129 |
