3WO5
Crystal structure of S147Q of Rv2613c from Mycobacterium tuberculosis
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0003877 | molecular_function | ATP:ADP adenylyltransferase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0008796 | molecular_function | bis(5'-nucleosyl)-tetraphosphatase activity |
| A | 0015967 | biological_process | diadenosine tetraphosphate catabolic process |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016779 | molecular_function | nucleotidyltransferase activity |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0003877 | molecular_function | ATP:ADP adenylyltransferase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0005886 | cellular_component | plasma membrane |
| B | 0008796 | molecular_function | bis(5'-nucleosyl)-tetraphosphatase activity |
| B | 0015967 | biological_process | diadenosine tetraphosphate catabolic process |
| B | 0016740 | molecular_function | transferase activity |
| B | 0016779 | molecular_function | nucleotidyltransferase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE PO4 A 301 |
| Chain | Residue |
| A | ASN139 |
| A | GLY145 |
| A | GLY146 |
| A | GLN147 |
| A | LEU148 |
| A | HIS153 |
| A | HIS155 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE PG4 A 302 |
| Chain | Residue |
| A | GLY69 |
| A | LEU70 |
| A | MET93 |
| A | HOH415 |
| A | ILE61 |
| A | LEU64 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE PO4 B 301 |
| Chain | Residue |
| B | ASN139 |
| B | GLY145 |
| B | LEU148 |
| B | HIS153 |
| B | HIS155 |
| B | HOH408 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PO4 B 302 |
| Chain | Residue |
| B | LYS120 |
| B | TRP191 |
| B | LYS196 |
| B | LEU197 |
| B | HOH414 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PG4 B 303 |
| Chain | Residue |
| B | GLY161 |
| B | GLY162 |
| B | GLN178 |
| B | HOH443 |
| B | HOH446 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 218 |
| Details | Domain: {"description":"HIT","evidences":[{"source":"PROSITE-ProRule","id":"PRU00464","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 8 |
| Details | Motif: {"description":"Histidine triad motif"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Tele-AMP-histidine intermediate","evidences":[{"evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
