Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CD A 301 |
| Chain | Residue |
| A | HIS40 |
| A | ASP43 |
| A | HIS151 |
| A | TAM309 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CD A 302 |
| Chain | Residue |
| A | MSE1 |
| A | GLU225 |
| A | CL305 |
| A | CL306 |
| A | CL307 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CA A 303 |
| Chain | Residue |
| A | HIS193 |
| A | ASP265 |
| A | HOH563 |
| A | HOH564 |
| A | HOH565 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CL A 304 |
| Chain | Residue |
| A | ARG152 |
| A | ARG153 |
| A | TAM308 |
| A | TAM308 |
| A | HEZ310 |
| A | HOH524 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL A 305 |
| Chain | Residue |
| A | GLU225 |
| A | CD302 |
| B | PHE2 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE CL A 306 |
| Chain | Residue |
| A | GLU225 |
| A | CD302 |
| A | CL307 |
| B | PHE2 |
| B | ASN4 |
| B | VAL5 |
| B | LYS14 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CL A 307 |
| Chain | Residue |
| A | MSE1 |
| A | CD302 |
| A | CL306 |
| B | PHE2 |
| B | GLU3 |
| B | ASN4 |
| site_id | AC8 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE TAM A 308 |
| Chain | Residue |
| A | TYR116 |
| A | TYR116 |
| A | TYR116 |
| A | ARG153 |
| A | ARG153 |
| A | ARG153 |
| A | CL304 |
| A | CL304 |
| A | HEZ310 |
| A | HEZ310 |
| A | HEZ310 |
| A | HOH463 |
| A | HOH463 |
| A | HOH463 |
| site_id | AC9 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE TAM A 309 |
| Chain | Residue |
| A | HIS40 |
| A | ASP42 |
| A | ASP43 |
| A | ILE46 |
| A | HIS151 |
| A | TYR191 |
| A | GLN218 |
| A | HIS259 |
| A | ILE260 |
| A | CD301 |
| A | HEZ315 |
| A | HOH456 |
| A | HOH465 |
| site_id | BC1 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE HEZ A 310 |
| Chain | Residue |
| A | PRO141 |
| A | PHE156 |
| A | CL304 |
| A | TAM308 |
| A | TAM308 |
| A | TAM308 |
| A | HOH413 |
| A | HOH463 |
| site_id | BC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE HEZ A 311 |
| Chain | Residue |
| A | PRO195 |
| A | ASN196 |
| A | TYR197 |
| A | ILE198 |
| A | ILE242 |
| site_id | BC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE HEZ A 312 |
| Chain | Residue |
| A | PHE237 |
| A | GLU240 |
| A | LYS241 |
| A | HOH533 |
| site_id | BC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE HE2 A 313 |
| Chain | Residue |
| A | GLU93 |
| A | VAL101 |
| A | LYS103 |
| A | ILE104 |
| A | HOH496 |
| site_id | BC5 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE HEZ A 314 |
| Chain | Residue |
| A | GLU113 |
| A | PRO115 |
| A | TYR116 |
| A | ARG153 |
| A | HOH428 |
| A | HOH435 |
| A | HOH523 |
| site_id | BC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE HEZ A 315 |
| Chain | Residue |
| A | GLN218 |
| A | TRP227 |
| A | TAM309 |
| site_id | BC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE HEZ A 316 |
| Chain | Residue |
| A | HOH530 |
| A | HOH532 |
| A | LEU20 |
| A | PHE22 |
| A | ASN23 |
| A | PRO254 |
| site_id | BC8 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE HEZ A 317 |
| Chain | Residue |
| A | GLN166 |
| A | SER183 |
| A | VAL184 |
| A | SER185 |
| A | PHE186 |
| A | ILE187 |
| A | MSE253 |
| A | HEZ319 |
| A | HOH426 |
| site_id | BC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE HEZ A 318 |
| Chain | Residue |
| A | SER6 |
| A | MSE236 |
| A | GLU240 |
| A | GLY243 |
| A | VAL244 |
| A | ARG245 |
| site_id | CC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE HEZ A 319 |
| Chain | Residue |
| A | HIS148 |
| A | ILE159 |
| A | ALA163 |
| A | ILE187 |
| A | GLY255 |
| A | HEZ317 |
| site_id | CC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CD B 301 |
| Chain | Residue |
| B | HIS40 |
| B | ASP43 |
| B | HIS151 |
| B | TAM309 |
| site_id | CC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CD B 302 |
| Chain | Residue |
| B | MSE1 |
| B | GLU225 |
| B | CL305 |
| B | CL306 |
| B | CL307 |
| site_id | CC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CA B 303 |
| Chain | Residue |
| B | HIS193 |
| B | ASP265 |
| B | HOH554 |
| B | HOH555 |
| B | HOH556 |
| site_id | CC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CL B 304 |
| Chain | Residue |
| B | ARG152 |
| B | ARG153 |
| B | TAM308 |
| B | TAM308 |
| B | TAM308 |
| B | HEZ312 |
| site_id | CC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE CL B 305 |
| Chain | Residue |
| A | PHE2 |
| A | ASN4 |
| A | VAL5 |
| A | LYS14 |
| B | GLU225 |
| B | CD302 |
| B | CL306 |
| site_id | CC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CL B 306 |
| Chain | Residue |
| A | PHE2 |
| A | GLU3 |
| A | ASN4 |
| B | MSE1 |
| B | CD302 |
| B | CL305 |
| site_id | CC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL B 307 |
| Chain | Residue |
| A | PHE2 |
| B | GLU225 |
| B | CD302 |
| site_id | CC9 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE TAM B 308 |
| Chain | Residue |
| B | TYR116 |
| B | TYR116 |
| B | ARG153 |
| B | ARG153 |
| B | ARG153 |
| B | CL304 |
| B | CL304 |
| B | CL304 |
| B | HEZ312 |
| B | HEZ312 |
| B | HEZ312 |
| B | HEZ313 |
| B | HEZ313 |
| B | HOH531 |
| B | HOH531 |
| B | HOH531 |
| site_id | DC1 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE TAM B 309 |
| Chain | Residue |
| B | HIS40 |
| B | ASP42 |
| B | ASP43 |
| B | ILE46 |
| B | ARG88 |
| B | HIS151 |
| B | TYR191 |
| B | GLN218 |
| B | HIS259 |
| B | ILE260 |
| B | CD301 |
| B | HOH452 |
| B | HOH463 |
| site_id | DC2 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE HEZ B 310 |
| Chain | Residue |
| B | GLN166 |
| B | SER183 |
| B | VAL184 |
| B | PHE186 |
| B | ILE187 |
| B | MSE253 |
| B | HEZ314 |
| B | HOH428 |
| B | HOH530 |
| site_id | DC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE HEZ B 311 |
| Chain | Residue |
| B | PRO195 |
| B | ASN196 |
| B | TYR197 |
| B | ILE198 |
| B | LYS241 |
| B | ILE242 |
| site_id | DC4 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE HEZ B 312 |
| Chain | Residue |
| B | PRO141 |
| B | PHE156 |
| B | CL304 |
| B | TAM308 |
| B | TAM308 |
| B | TAM308 |
| B | HOH412 |
| B | HOH531 |
| site_id | DC5 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE HEZ B 313 |
| Chain | Residue |
| B | GLU113 |
| B | PRO115 |
| B | TYR116 |
| B | ARG153 |
| B | TAM308 |
| B | TAM308 |
| B | HEZ320 |
| B | HOH536 |
| site_id | DC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE HEZ B 314 |
| Chain | Residue |
| B | SER147 |
| B | ILE159 |
| B | ALA163 |
| B | HEZ310 |
| B | HEZ318 |
| site_id | DC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE HEZ B 315 |
| Chain | Residue |
| B | GLU93 |
| B | VAL101 |
| B | LYS103 |
| B | ILE104 |
| B | HOH486 |
| site_id | DC8 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE HE2 B 316 |
| Chain | Residue |
| B | ILE46 |
| B | GLY47 |
| B | TYR191 |
| B | LYS208 |
| B | LEU231 |
| B | VAL234 |
| B | THR235 |
| B | TYR238 |
| B | GLY247 |
| B | GLU248 |
| B | ILE260 |
| B | HOH432 |
| site_id | DC9 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE HEZ B 317 |
| Chain | Residue |
| A | ARG89 |
| B | ASP76 |
| B | GLU77 |
| B | LYS78 |
| B | LEU79 |
| B | SER80 |
| B | PRO168 |
| B | ASN169 |
| B | HOH434 |
| B | HOH535 |
| site_id | EC1 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE HEZ B 318 |
| Chain | Residue |
| B | MSE72 |
| B | ASP111 |
| B | THR112 |
| B | HIS148 |
| B | ALA163 |
| B | GLN166 |
| B | LEU167 |
| B | HEZ314 |
| B | HOH452 |
| site_id | EC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE HEZ B 319 |
| Chain | Residue |
| B | LEU20 |
| B | PHE22 |
| B | PRO254 |
| B | GLY255 |
| B | HOH426 |
| site_id | EC3 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE HEZ B 320 |
| Chain | Residue |
| A | HOH445 |
| B | TYR109 |
| B | ARG110 |
| B | GLU113 |
| B | PRO115 |
| B | ARG118 |
| B | HEZ313 |
| B | HOH431 |
| B | HOH439 |
| B | HOH506 |
| site_id | EC4 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE HEZ B 321 |
| Chain | Residue |
| B | TYR145 |
| B | HOH442 |
| site_id | EC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE HEZ B 322 |
| Chain | Residue |
| B | PHE8 |
| B | PHE237 |
| B | GLU240 |
| B | LYS241 |
| B | HOH511 |
