3WIC
Structure of a substrate/cofactor-unbound glucose dehydrogenase
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0005534 | molecular_function | galactose binding |
| A | 0005536 | molecular_function | D-glucose binding |
| A | 0008270 | molecular_function | zinc ion binding |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0019595 | biological_process | non-phosphorylated glucose catabolic process |
| A | 0033498 | biological_process | galactose catabolic process via D-galactonate |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0047910 | molecular_function | galactose 1-dehydrogenase (NADP+) activity |
| A | 0047934 | molecular_function | glucose 1-dehydrogenase (NAD+) activity |
| A | 0047935 | molecular_function | glucose 1-dehydrogenase (NADP+) activity |
| A | 0047936 | molecular_function | glucose 1-dehydrogenase [NAD(P)+] activity |
| A | 0051262 | biological_process | protein tetramerization |
| A | 0070401 | molecular_function | NADP+ binding |
| A | 0070403 | molecular_function | NAD+ binding |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0005534 | molecular_function | galactose binding |
| B | 0005536 | molecular_function | D-glucose binding |
| B | 0008270 | molecular_function | zinc ion binding |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0019595 | biological_process | non-phosphorylated glucose catabolic process |
| B | 0033498 | biological_process | galactose catabolic process via D-galactonate |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0047910 | molecular_function | galactose 1-dehydrogenase (NADP+) activity |
| B | 0047934 | molecular_function | glucose 1-dehydrogenase (NAD+) activity |
| B | 0047935 | molecular_function | glucose 1-dehydrogenase (NADP+) activity |
| B | 0047936 | molecular_function | glucose 1-dehydrogenase [NAD(P)+] activity |
| B | 0051262 | biological_process | protein tetramerization |
| B | 0070401 | molecular_function | NADP+ binding |
| B | 0070403 | molecular_function | NAD+ binding |
| C | 0000166 | molecular_function | nucleotide binding |
| C | 0005534 | molecular_function | galactose binding |
| C | 0005536 | molecular_function | D-glucose binding |
| C | 0008270 | molecular_function | zinc ion binding |
| C | 0016491 | molecular_function | oxidoreductase activity |
| C | 0019595 | biological_process | non-phosphorylated glucose catabolic process |
| C | 0033498 | biological_process | galactose catabolic process via D-galactonate |
| C | 0046872 | molecular_function | metal ion binding |
| C | 0047910 | molecular_function | galactose 1-dehydrogenase (NADP+) activity |
| C | 0047934 | molecular_function | glucose 1-dehydrogenase (NAD+) activity |
| C | 0047935 | molecular_function | glucose 1-dehydrogenase (NADP+) activity |
| C | 0047936 | molecular_function | glucose 1-dehydrogenase [NAD(P)+] activity |
| C | 0051262 | biological_process | protein tetramerization |
| C | 0070401 | molecular_function | NADP+ binding |
| C | 0070403 | molecular_function | NAD+ binding |
| D | 0000166 | molecular_function | nucleotide binding |
| D | 0005534 | molecular_function | galactose binding |
| D | 0005536 | molecular_function | D-glucose binding |
| D | 0008270 | molecular_function | zinc ion binding |
| D | 0016491 | molecular_function | oxidoreductase activity |
| D | 0019595 | biological_process | non-phosphorylated glucose catabolic process |
| D | 0033498 | biological_process | galactose catabolic process via D-galactonate |
| D | 0046872 | molecular_function | metal ion binding |
| D | 0047910 | molecular_function | galactose 1-dehydrogenase (NADP+) activity |
| D | 0047934 | molecular_function | glucose 1-dehydrogenase (NAD+) activity |
| D | 0047935 | molecular_function | glucose 1-dehydrogenase (NADP+) activity |
| D | 0047936 | molecular_function | glucose 1-dehydrogenase [NAD(P)+] activity |
| D | 0051262 | biological_process | protein tetramerization |
| D | 0070401 | molecular_function | NADP+ binding |
| D | 0070403 | molecular_function | NAD+ binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE ZN A 1001 |
| Chain | Residue |
| A | CYS41 |
| A | HIS68 |
| A | GLU69 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 1002 |
| Chain | Residue |
| A | CYS99 |
| A | CYS102 |
| A | CYS110 |
| A | ASP116 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PGO A 1003 |
| Chain | Residue |
| A | ARG130 |
| A | ILE133 |
| A | TYR134 |
| A | ARG95 |
| A | HIS126 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE 1PE A 1004 |
| Chain | Residue |
| A | ILE104 |
| A | ARG106 |
| A | HOH1110 |
| B | GLN178 |
| C | LYS173 |
| site_id | AC5 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE 1PE A 1005 |
| Chain | Residue |
| A | ILE137 |
| A | LEU140 |
| A | LYS142 |
| A | ASN144 |
| A | LYS309 |
| A | VAL313 |
| B | ASP181 |
| B | ILE185 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN B 1001 |
| Chain | Residue |
| B | CYS41 |
| B | HIS68 |
| B | GLU69 |
| B | HOH1106 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN B 1002 |
| Chain | Residue |
| B | CYS99 |
| B | CYS102 |
| B | CYS110 |
| B | ASP116 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE PGO B 1003 |
| Chain | Residue |
| B | ARG95 |
| B | HIS126 |
| B | ARG130 |
| B | ILE133 |
| B | TYR134 |
| B | ASP135 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE PGO B 1004 |
| Chain | Residue |
| B | PHE88 |
| B | ASP145 |
| B | PRO146 |
| B | LEU148 |
| B | GLY149 |
| B | HOH1148 |
| site_id | BC1 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE 1PE B 1005 |
| Chain | Residue |
| A | GLN178 |
| A | HOH1143 |
| B | ARG106 |
| B | GLU166 |
| B | HIS311 |
| B | HOH1141 |
| D | LYS173 |
| D | ARG174 |
| site_id | BC2 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE 1PE B 1006 |
| Chain | Residue |
| A | ILE185 |
| B | TYR82 |
| B | ILE137 |
| B | GLN138 |
| B | LEU140 |
| B | VAL141 |
| B | LYS142 |
| B | ASN144 |
| B | LYS309 |
| site_id | BC3 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE 1PE B 1007 |
| Chain | Residue |
| B | LYS173 |
| B | ARG174 |
| B | HOH1107 |
| B | HOH1139 |
| C | LYS173 |
| C | ILE176 |
| C | GLN178 |
| C | ASN179 |
| D | ILE104 |
| D | ARG106 |
| D | HOH1119 |
| site_id | BC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN C 1001 |
| Chain | Residue |
| C | CYS41 |
| C | HIS68 |
| C | GLU69 |
| C | GLU156 |
| site_id | BC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN C 1002 |
| Chain | Residue |
| C | CYS99 |
| C | CYS102 |
| C | CYS110 |
| C | ASP116 |
| site_id | BC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE PGO C 1003 |
| Chain | Residue |
| C | ARG95 |
| C | HIS126 |
| C | ARG130 |
| C | ILE133 |
| C | TYR134 |
| C | HOH1109 |
| site_id | BC7 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE 1PE C 1004 |
| Chain | Residue |
| A | LYS173 |
| A | ARG174 |
| A | HOH1115 |
| C | ILE104 |
| C | LYS173 |
| C | HOH1160 |
| D | LYS173 |
| D | ILE176 |
| D | GLN178 |
| D | ASN179 |
| D | SER182 |
| site_id | BC8 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE 1PE C 1005 |
| Chain | Residue |
| C | ILE137 |
| C | LEU140 |
| C | VAL141 |
| C | LYS142 |
| C | LYS309 |
| C | HOH1151 |
| D | ASP181 |
| D | ILE185 |
| C | TYR82 |
| site_id | BC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN D 1001 |
| Chain | Residue |
| D | CYS41 |
| D | HIS68 |
| D | GLU69 |
| D | GLU156 |
| site_id | CC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN D 1002 |
| Chain | Residue |
| D | CYS99 |
| D | CYS102 |
| D | CYS110 |
| D | ASP116 |
| site_id | CC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE PGO D 1003 |
| Chain | Residue |
| D | ALA120 |
| D | HIS126 |
| D | PHE128 |
| D | ARG130 |
| D | TYR134 |
| D | ASP135 |
| site_id | CC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PGO D 1004 |
| Chain | Residue |
| D | PHE88 |
| D | ASP145 |
| D | PRO146 |
| D | LEU148 |
| D | GLY149 |
| site_id | CC4 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE 1PE D 1005 |
| Chain | Residue |
| C | ASN179 |
| C | ASP181 |
| D | ILE137 |
| D | LEU140 |
| D | LYS142 |
| D | ASN144 |
| D | LYS309 |
| D | VAL313 |
| D | ASP317 |
| D | HOH1155 |
