3WHC
Crystal structure of a transcriptional regulator FadR from Bacillus subtilis in complex with stearoyl-CoA
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000976 | molecular_function | transcription cis-regulatory region binding |
| A | 0003677 | molecular_function | DNA binding |
| A | 0003700 | molecular_function | DNA-binding transcription factor activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006355 | biological_process | regulation of DNA-templated transcription |
| B | 0000976 | molecular_function | transcription cis-regulatory region binding |
| B | 0003677 | molecular_function | DNA binding |
| B | 0003700 | molecular_function | DNA-binding transcription factor activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006355 | biological_process | regulation of DNA-templated transcription |
| C | 0000976 | molecular_function | transcription cis-regulatory region binding |
| C | 0003677 | molecular_function | DNA binding |
| C | 0003700 | molecular_function | DNA-binding transcription factor activity |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0006355 | biological_process | regulation of DNA-templated transcription |
| D | 0000976 | molecular_function | transcription cis-regulatory region binding |
| D | 0003677 | molecular_function | DNA binding |
| D | 0003700 | molecular_function | DNA-binding transcription factor activity |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0006355 | biological_process | regulation of DNA-templated transcription |
| E | 0000976 | molecular_function | transcription cis-regulatory region binding |
| E | 0003677 | molecular_function | DNA binding |
| E | 0003700 | molecular_function | DNA-binding transcription factor activity |
| E | 0005737 | cellular_component | cytoplasm |
| E | 0006355 | biological_process | regulation of DNA-templated transcription |
| F | 0000976 | molecular_function | transcription cis-regulatory region binding |
| F | 0003677 | molecular_function | DNA binding |
| F | 0003700 | molecular_function | DNA-binding transcription factor activity |
| F | 0005737 | cellular_component | cytoplasm |
| F | 0006355 | biological_process | regulation of DNA-templated transcription |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 21 |
| Details | BINDING SITE FOR RESIDUE ST9 A 201 |
| Chain | Residue |
| A | LEU57 |
| A | LEU127 |
| A | ARG150 |
| A | ARG153 |
| A | HOH307 |
| B | GLU162 |
| B | THR165 |
| B | THR166 |
| B | MET169 |
| B | ASN170 |
| B | LYS173 |
| A | LYS61 |
| B | TYR174 |
| B | LEU179 |
| A | HIS90 |
| A | LEU93 |
| A | THR104 |
| A | ARG109 |
| A | ARG116 |
| A | ASN120 |
| A | LYS124 |
| site_id | AC2 |
| Number of Residues | 21 |
| Details | BINDING SITE FOR RESIDUE ST9 B 201 |
| Chain | Residue |
| A | GLU162 |
| A | THR165 |
| A | THR166 |
| A | MET169 |
| A | ASN170 |
| A | LYS173 |
| A | TYR174 |
| A | LEU179 |
| A | HOH332 |
| A | HOH333 |
| B | LEU57 |
| B | PHE65 |
| B | HIS90 |
| B | THR104 |
| B | ARG109 |
| B | ARG116 |
| B | ASN120 |
| B | LYS124 |
| B | LEU127 |
| B | ARG150 |
| B | ARG153 |
| site_id | AC3 |
| Number of Residues | 21 |
| Details | BINDING SITE FOR RESIDUE ST9 C 201 |
| Chain | Residue |
| C | LYS61 |
| C | HIS90 |
| C | VAL103 |
| C | THR104 |
| C | ARG109 |
| C | ARG116 |
| C | ASN120 |
| C | LYS124 |
| C | LEU127 |
| C | ARG150 |
| C | LEU151 |
| C | ARG153 |
| C | GLN154 |
| C | PHE157 |
| D | GLU162 |
| D | THR165 |
| D | THR166 |
| D | MET169 |
| D | ASN170 |
| D | TYR174 |
| D | LEU179 |
| site_id | AC4 |
| Number of Residues | 23 |
| Details | BINDING SITE FOR RESIDUE ST9 D 201 |
| Chain | Residue |
| C | GLU162 |
| C | THR165 |
| C | THR166 |
| C | MET169 |
| C | ASN170 |
| C | LYS173 |
| C | TYR174 |
| C | LEU179 |
| D | PHE58 |
| D | LYS61 |
| D | PHE65 |
| D | HIS90 |
| D | THR104 |
| D | ARG109 |
| D | ARG116 |
| D | ASN120 |
| D | LYS124 |
| D | LEU127 |
| D | ARG150 |
| D | LEU151 |
| D | ARG153 |
| D | GLN154 |
| D | PHE157 |
| site_id | AC5 |
| Number of Residues | 21 |
| Details | BINDING SITE FOR RESIDUE ST9 E 201 |
| Chain | Residue |
| F | GLU162 |
| F | THR165 |
| F | THR166 |
| F | MET169 |
| F | ASN170 |
| F | LYS173 |
| F | TYR174 |
| F | LEU179 |
| A | LYS76 |
| E | PHE58 |
| E | LYS61 |
| E | MET62 |
| E | HIS90 |
| E | LEU100 |
| E | THR104 |
| E | ARG109 |
| E | ARG116 |
| E | ASN120 |
| E | LEU127 |
| E | ARG150 |
| E | ARG153 |
| site_id | AC6 |
| Number of Residues | 23 |
| Details | BINDING SITE FOR RESIDUE ST9 F 201 |
| Chain | Residue |
| A | LYS7 |
| A | GLN10 |
| A | GLY37 |
| E | GLU162 |
| E | THR165 |
| E | THR166 |
| E | MET169 |
| E | ASN170 |
| E | TYR174 |
| F | LYS61 |
| F | HIS90 |
| F | LEU93 |
| F | LEU100 |
| F | THR104 |
| F | LEU108 |
| F | ARG109 |
| F | ARG116 |
| F | ASN120 |
| F | LYS124 |
| F | LEU127 |
| F | ARG150 |
| F | ARG153 |
| F | GLN154 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 180 |
| Details | Domain: {"description":"HTH tetR-type","evidences":[{"source":"PROSITE-ProRule","id":"PRU00335","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 114 |
| Details | DNA binding: {"description":"H-T-H motif","evidences":[{"source":"PROSITE-ProRule","id":"PRU00335","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
