3WH2
Human Mincle in complex with citrate
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CA A 301 |
| Chain | Residue |
| A | GLU169 |
| A | ASN171 |
| A | ASN193 |
| A | ASP194 |
| A | FLC303 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 302 |
| Chain | Residue |
| A | HOH426 |
| A | HOH437 |
| A | VAL117 |
| A | ASN119 |
| A | GLU123 |
| A | GLU206 |
| site_id | AC3 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE FLC A 303 |
| Chain | Residue |
| A | GLU169 |
| A | ASN171 |
| A | ASN172 |
| A | ARG183 |
| A | ASN193 |
| A | ASP194 |
| A | VAL195 |
| A | THR196 |
| A | CA301 |
| A | HOH490 |
| A | HOH499 |
| A | HOH534 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 119 |
| Details | Domain: {"description":"C-type lectin","evidences":[{"source":"PROSITE-ProRule","id":"PRU00040","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Motif: {"description":"Confers specificity for glucose/mannose-type carbohydrates","evidences":[{"source":"PubMed","id":"24101491","evidenceCode":"ECO:0000303"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 8 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"24101491","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
