3WFJ
The complex structure of D-mandelate dehydrogenase with NADH
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0008677 | molecular_function | 2-dehydropantoate 2-reductase activity |
| A | 0015940 | biological_process | pantothenate biosynthetic process |
| A | 0050661 | molecular_function | NADP binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0008677 | molecular_function | 2-dehydropantoate 2-reductase activity |
| B | 0015940 | biological_process | pantothenate biosynthetic process |
| B | 0050661 | molecular_function | NADP binding |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0008677 | molecular_function | 2-dehydropantoate 2-reductase activity |
| C | 0015940 | biological_process | pantothenate biosynthetic process |
| C | 0050661 | molecular_function | NADP binding |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0008677 | molecular_function | 2-dehydropantoate 2-reductase activity |
| D | 0015940 | biological_process | pantothenate biosynthetic process |
| D | 0050661 | molecular_function | NADP binding |
| E | 0005737 | cellular_component | cytoplasm |
| E | 0008677 | molecular_function | 2-dehydropantoate 2-reductase activity |
| E | 0015940 | biological_process | pantothenate biosynthetic process |
| E | 0050661 | molecular_function | NADP binding |
| F | 0005737 | cellular_component | cytoplasm |
| F | 0008677 | molecular_function | 2-dehydropantoate 2-reductase activity |
| F | 0015940 | biological_process | pantothenate biosynthetic process |
| F | 0050661 | molecular_function | NADP binding |
| G | 0005737 | cellular_component | cytoplasm |
| G | 0008677 | molecular_function | 2-dehydropantoate 2-reductase activity |
| G | 0015940 | biological_process | pantothenate biosynthetic process |
| G | 0050661 | molecular_function | NADP binding |
| H | 0005737 | cellular_component | cytoplasm |
| H | 0008677 | molecular_function | 2-dehydropantoate 2-reductase activity |
| H | 0015940 | biological_process | pantothenate biosynthetic process |
| H | 0050661 | molecular_function | NADP binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE NAD A 401 |
| Chain | Residue |
| A | GLY9 |
| A | LEU104 |
| A | ASN105 |
| A | TRP129 |
| A | THR130 |
| A | ALA131 |
| A | ARG270 |
| A | GLU273 |
| A | HOH506 |
| A | ALA10 |
| A | MET11 |
| A | ASP30 |
| A | TRP32 |
| A | PHE77 |
| A | THR78 |
| A | LYS79 |
| A | GLN82 |
| site_id | AC2 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE NAD B 401 |
| Chain | Residue |
| B | GLY9 |
| B | ALA10 |
| B | MET11 |
| B | ASP30 |
| B | TRP32 |
| B | PHE77 |
| B | THR78 |
| B | LYS79 |
| B | GLN82 |
| B | LEU104 |
| B | ASN105 |
| B | TRP129 |
| B | THR130 |
| B | ALA131 |
| B | LEU133 |
| B | ARG270 |
| B | GLU273 |
| B | HOH515 |
| site_id | AC3 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE NAD C 401 |
| Chain | Residue |
| C | GLY9 |
| C | ALA10 |
| C | MET11 |
| C | ASP30 |
| C | TRP32 |
| C | PHE77 |
| C | THR78 |
| C | LYS79 |
| C | GLN82 |
| C | LEU104 |
| C | ASN105 |
| C | TRP129 |
| C | THR130 |
| C | ALA131 |
| C | ARG270 |
| C | GLU273 |
| site_id | AC4 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE NAD D 401 |
| Chain | Residue |
| D | GLY9 |
| D | ALA10 |
| D | MET11 |
| D | ASP30 |
| D | TRP32 |
| D | PHE77 |
| D | THR78 |
| D | LYS79 |
| D | GLN82 |
| D | LEU104 |
| D | ASN105 |
| D | TRP129 |
| D | THR130 |
| D | ALA131 |
| D | LEU133 |
| D | ARG270 |
| D | GLU273 |
| site_id | AC5 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE NAD E 401 |
| Chain | Residue |
| E | GLY9 |
| E | ALA10 |
| E | MET11 |
| E | ASP30 |
| E | TRP32 |
| E | PHE77 |
| E | THR78 |
| E | LYS79 |
| E | GLN82 |
| E | LEU104 |
| E | ASN105 |
| E | TRP129 |
| E | THR130 |
| E | ALA131 |
| E | LYS187 |
| E | ARG270 |
| E | GLU273 |
| E | HOH518 |
| E | HOH525 |
| site_id | AC6 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE NAD F 401 |
| Chain | Residue |
| F | TRP129 |
| F | THR130 |
| F | ALA131 |
| F | LEU133 |
| F | ARG270 |
| F | GLU273 |
| F | HOH527 |
| F | GLY9 |
| F | ALA10 |
| F | MET11 |
| F | ASP30 |
| F | TRP32 |
| F | PHE77 |
| F | THR78 |
| F | LYS79 |
| F | GLN82 |
| F | LEU104 |
| F | ASN105 |
| F | THR127 |
| site_id | AC7 |
| Number of Residues | 20 |
| Details | BINDING SITE FOR RESIDUE NAD G 401 |
| Chain | Residue |
| G | GLY9 |
| G | ALA10 |
| G | MET11 |
| G | ASP30 |
| G | TRP32 |
| G | PHE77 |
| G | THR78 |
| G | LYS79 |
| G | GLN82 |
| G | LEU104 |
| G | ASN105 |
| G | THR127 |
| G | TRP129 |
| G | THR130 |
| G | ALA131 |
| G | LYS187 |
| G | ARG270 |
| G | GLU273 |
| G | HOH504 |
| G | HOH522 |
| site_id | AC8 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE NAD H 401 |
| Chain | Residue |
| H | GLY9 |
| H | ALA10 |
| H | MET11 |
| H | ASP30 |
| H | TRP32 |
| H | PHE77 |
| H | THR78 |
| H | LYS79 |
| H | GLN82 |
| H | LEU104 |
| H | ASN105 |
| H | TRP129 |
| H | THR130 |
| H | ALA131 |
| H | LEU133 |
| H | ARG270 |
| H | GLU273 |
