3WFJ

The complex structure of D-mandelate dehydrogenase with NADH

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0005737	cellular_component	cytoplasm
A	0008677	molecular_function	2-dehydropantoate 2-reductase activity
A	0015940	biological_process	pantothenate biosynthetic process
A	0016491	molecular_function	oxidoreductase activity
A	0050661	molecular_function	NADP binding
B	0000166	molecular_function	nucleotide binding
B	0005737	cellular_component	cytoplasm
B	0008677	molecular_function	2-dehydropantoate 2-reductase activity
B	0015940	biological_process	pantothenate biosynthetic process
B	0016491	molecular_function	oxidoreductase activity
B	0050661	molecular_function	NADP binding
C	0000166	molecular_function	nucleotide binding
C	0005737	cellular_component	cytoplasm
C	0008677	molecular_function	2-dehydropantoate 2-reductase activity
C	0015940	biological_process	pantothenate biosynthetic process
C	0016491	molecular_function	oxidoreductase activity
C	0050661	molecular_function	NADP binding
D	0000166	molecular_function	nucleotide binding
D	0005737	cellular_component	cytoplasm
D	0008677	molecular_function	2-dehydropantoate 2-reductase activity
D	0015940	biological_process	pantothenate biosynthetic process
D	0016491	molecular_function	oxidoreductase activity
D	0050661	molecular_function	NADP binding
E	0000166	molecular_function	nucleotide binding
E	0005737	cellular_component	cytoplasm
E	0008677	molecular_function	2-dehydropantoate 2-reductase activity
E	0015940	biological_process	pantothenate biosynthetic process
E	0016491	molecular_function	oxidoreductase activity
E	0050661	molecular_function	NADP binding
F	0000166	molecular_function	nucleotide binding
F	0005737	cellular_component	cytoplasm
F	0008677	molecular_function	2-dehydropantoate 2-reductase activity
F	0015940	biological_process	pantothenate biosynthetic process
F	0016491	molecular_function	oxidoreductase activity
F	0050661	molecular_function	NADP binding
G	0000166	molecular_function	nucleotide binding
G	0005737	cellular_component	cytoplasm
G	0008677	molecular_function	2-dehydropantoate 2-reductase activity
G	0015940	biological_process	pantothenate biosynthetic process
G	0016491	molecular_function	oxidoreductase activity
G	0050661	molecular_function	NADP binding
H	0000166	molecular_function	nucleotide binding
H	0005737	cellular_component	cytoplasm
H	0008677	molecular_function	2-dehydropantoate 2-reductase activity
H	0015940	biological_process	pantothenate biosynthetic process
H	0016491	molecular_function	oxidoreductase activity
H	0050661	molecular_function	NADP binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	17
Details	BINDING SITE FOR RESIDUE NAD A 401

Chain	Residue
A	GLY9
A	LEU104
A	ASN105
A	TRP129
A	THR130
A	ALA131
A	ARG270
A	GLU273
A	HOH506
A	ALA10
A	MET11
A	ASP30
A	TRP32
A	PHE77
A	THR78
A	LYS79
A	GLN82

---

site_id	AC2
Number of Residues	18
Details	BINDING SITE FOR RESIDUE NAD B 401

Chain	Residue
B	GLY9
B	ALA10
B	MET11
B	ASP30
B	TRP32
B	PHE77
B	THR78
B	LYS79
B	GLN82
B	LEU104
B	ASN105
B	TRP129
B	THR130
B	ALA131
B	LEU133
B	ARG270
B	GLU273
B	HOH515

---

site_id	AC3
Number of Residues	16
Details	BINDING SITE FOR RESIDUE NAD C 401

Chain	Residue
C	GLY9
C	ALA10
C	MET11
C	ASP30
C	TRP32
C	PHE77
C	THR78
C	LYS79
C	GLN82
C	LEU104
C	ASN105
C	TRP129
C	THR130
C	ALA131
C	ARG270
C	GLU273

---

site_id	AC4
Number of Residues	17
Details	BINDING SITE FOR RESIDUE NAD D 401

Chain	Residue
D	GLY9
D	ALA10
D	MET11
D	ASP30
D	TRP32
D	PHE77
D	THR78
D	LYS79
D	GLN82
D	LEU104
D	ASN105
D	TRP129
D	THR130
D	ALA131
D	LEU133
D	ARG270
D	GLU273

---

site_id	AC5
Number of Residues	19
Details	BINDING SITE FOR RESIDUE NAD E 401

Chain	Residue
E	GLY9
E	ALA10
E	MET11
E	ASP30
E	TRP32
E	PHE77
E	THR78
E	LYS79
E	GLN82
E	LEU104
E	ASN105
E	TRP129
E	THR130
E	ALA131
E	LYS187
E	ARG270
E	GLU273
E	HOH518
E	HOH525

---

site_id	AC6
Number of Residues	19
Details	BINDING SITE FOR RESIDUE NAD F 401

Chain	Residue
F	TRP129
F	THR130
F	ALA131
F	LEU133
F	ARG270
F	GLU273
F	HOH527
F	GLY9
F	ALA10
F	MET11
F	ASP30
F	TRP32
F	PHE77
F	THR78
F	LYS79
F	GLN82
F	LEU104
F	ASN105
F	THR127

---

site_id	AC7
Number of Residues	20
Details	BINDING SITE FOR RESIDUE NAD G 401

Chain	Residue
G	GLY9
G	ALA10
G	MET11
G	ASP30
G	TRP32
G	PHE77
G	THR78
G	LYS79
G	GLN82
G	LEU104
G	ASN105
G	THR127
G	TRP129
G	THR130
G	ALA131
G	LYS187
G	ARG270
G	GLU273
G	HOH504
G	HOH522

---

site_id	AC8
Number of Residues	17
Details	BINDING SITE FOR RESIDUE NAD H 401

Chain	Residue
H	GLY9
H	ALA10
H	MET11
H	ASP30
H	TRP32
H	PHE77
H	THR78
H	LYS79
H	GLN82
H	LEU104
H	ASN105
H	TRP129
H	THR130
H	ALA131
H	LEU133
H	ARG270
H	GLU273

---