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3WFG

Mineralocorticoid receptor ligand-binding domain with compuond 2e

Functional Information from PDB Data
site_idAC1
Number of Residues18
DetailsBINDING SITE FOR RESIDUE WFG A 1001
ChainResidue
ALEU769
ACYS849
AMET852
ALEU938
APHE941
ACYS942
ATHR945
AVAL954
APHE956
AHOH1115
AASN770
AALA773
ATRP806
AMET807
ASER811
ALEU814
AMET845
ALEU848

site_idAC2
Number of Residues7
DetailsBINDING SITE FOR RESIDUE EDO A 1002
ChainResidue
ATYR751
AALA752
AARG771
ALYS775
AASP884
AHOH1153
AHOH1186

site_idAC3
Number of Residues6
DetailsBINDING SITE FOR RESIDUE EDO A 1003
ChainResidue
AGLN889
ASER949
ALYS953
AVAL954
AHOH1173
AHOH1289

site_idAC4
Number of Residues3
DetailsBINDING SITE FOR RESIDUE EDO A 1004
ChainResidue
AGLN803
AGLU962
AILE963

site_idAC5
Number of Residues3
DetailsBINDING SITE FOR RESIDUE EDO A 1005
ChainResidue
AGLN889
ASER949
AHIS950

site_idAC6
Number of Residues7
DetailsBINDING SITE FOR RESIDUE EDO A 1006
ChainResidue
AGLN825
APHE826
AASN836
AGLU837
AMET840
AHIS853
AHOH1194

site_idAC7
Number of Residues5
DetailsBINDING SITE FOR RESIDUE EDO A 1007
ChainResidue
AILE745
ATRP783
AHOH1141
AHOH1258
AHOH1266

site_idAC8
Number of Residues5
DetailsBINDING SITE FOR RESIDUE EDO A 1008
ChainResidue
ATHR880
AHIS932
AVAL935
AHOH1152
AHOH1281

site_idAC9
Number of Residues5
DetailsBINDING SITE FOR RESIDUE EDO A 1009
ChainResidue
AALA844
AMET845
AGLU847
ALEU848
AHOH1170

site_idBC1
Number of Residues5
DetailsBINDING SITE FOR RESIDUE EDO A 1010
ChainResidue
ATHR865
AGLU868
AVAL907
AASN913
AHOH1216

site_idBC2
Number of Residues9
DetailsBINDING SITE FOR RESIDUE EDO A 1011
ChainResidue
ATYR754
AASP755
ALYS758
APRO759
AASP760
AASN764
ALEU765
ATHR768
AHOH1137

site_idBC3
Number of Residues4
DetailsBINDING SITE FOR RESIDUE EDO A 1012
ChainResidue
AGLN803
AASP966
ALYS970
AHOH1131

site_idBC4
Number of Residues3
DetailsBINDING SITE FOR RESIDUE EDO A 1013
ChainResidue
ATYR899
AGLU902
AHOH1138

site_idBC5
Number of Residues4
DetailsBINDING SITE FOR RESIDUE EDO A 1014
ChainResidue
ATHR800
ALYS970
AASN975
AHOH1214

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues3
DetailsBINDING: BINDING => ECO:0000269|PubMed:15908963, ECO:0000269|PubMed:15967794, ECO:0007744|PDB:1YA3, ECO:0007744|PDB:2AA5, ECO:0007744|PDB:2AA6
ChainResidueDetails
AASN770
AGLN776
AARG817

site_idSWS_FT_FI2
Number of Residues1
DetailsBINDING: BINDING => ECO:0000269|PubMed:15967794, ECO:0007744|PDB:2AA5, ECO:0007744|PDB:2AA6
ChainResidueDetails
ATHR945

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PDB entries from 2024-11-06

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