Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004310 | molecular_function | farnesyl-diphosphate farnesyltransferase activity |
| A | 0004311 | molecular_function | farnesyltranstransferase activity |
| A | 0008610 | biological_process | lipid biosynthetic process |
| A | 0009058 | biological_process | biosynthetic process |
| A | 0016765 | molecular_function | transferase activity, transferring alkyl or aryl (other than methyl) groups |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE MG A 401 |
| Chain | Residue |
| A | ASP80 |
| A | ASP84 |
| A | MG402 |
| A | HOH785 |
| A | HOH786 |
| A | HOH788 |
| A | HOH789 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE MG A 402 |
| Chain | Residue |
| A | ASP84 |
| A | MG401 |
| A | HOH783 |
| A | HOH784 |
| A | HOH785 |
| A | ASP80 |
| A | GLU83 |
| site_id | AC3 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE PS7 A 403 |
| Chain | Residue |
| A | ARG52 |
| A | SER53 |
| A | PHE54 |
| A | TYR73 |
| A | LEU76 |
| A | ARG77 |
| A | ASP80 |
| A | VAL175 |
| A | GLY180 |
| A | MET207 |
| A | GLN212 |
| A | ASN215 |
| A | TYR276 |
| A | HOH574 |
| A | HOH718 |
| A | HOH732 |
| A | HOH771 |
Functional Information from PROSITE/UniProt
| site_id | PS01044 |
| Number of Residues | 16 |
| Details | SQUALEN_PHYTOEN_SYN_1 Squalene and phytoene synthases signature 1. YChyVAGLVGigLsrL |
| Chain | Residue | Details |
| A | TYR171-LEU186 | |
| site_id | PS01045 |
| Number of Residues | 26 |
| Details | SQUALEN_PHYTOEN_SYN_2 Squalene and phytoene synthases signature 2. MGlflQkt.NIiRDYleDqqgg...ReFwP |
| Chain | Residue | Details |
| A | MET207-PRO232 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 20 |
| Details | TRANSMEM: Helical => ECO:0000255 |
| Chain | Residue | Details |
| A | SER284-TYR304 | |
| Chain | Residue | Details |
| A | ARG52 | |
| A | ARG77 | |
| A | ARG218 | |
| A | LYS315 | |
| A | ARG317 | |
| Chain | Residue | Details |
| A | ASP80 | |
| A | GLU83 | |
| A | ASP84 | |
Catalytic Information from CSA
| site_id | MCSA1 |
| Number of Residues | 4 |
| Details | M-CSA 264 |
| Chain | Residue | Details |
| A | TYR171 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
| A | ARG218 | electrostatic stabiliser, hydrogen bond donor, promote heterolysis |
| A | ARG228 | electrostatic stabiliser, hydrogen bond donor, promote heterolysis |
| A | PHE288 | polar/non-polar interaction, steric role, van der waals interaction |
