3WD1

Serratia marcescens Chitinase B complexed with syn-triazole inhibitor

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004553	molecular_function	hydrolase activity, hydrolyzing O-glycosyl compounds
A	0005576	cellular_component	extracellular region
A	0005975	biological_process	carbohydrate metabolic process
A	0008061	molecular_function	chitin binding
A	0030246	molecular_function	carbohydrate binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	8
Details	BINDING SITE FOR RESIDUE GOL A 501

Chain	Residue
A	THR3
A	ARG4
A	HIS46
A	ARG89
A	TYR208
A	SO4512
A	HOH659
A	HOH689

---

site_id	AC2
Number of Residues	8
Details	BINDING SITE FOR RESIDUE GOL A 502

Chain	Residue
A	PHE263
A	SER264
A	ARG439
A	TYR440
A	THR441
A	HOH735
A	HOH740
A	PRO260

---

site_id	AC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL A 503

Chain	Residue
A	ARG244
A	TRP252
A	PHE259
A	PRO260
A	SER261
A	HOH736

---

site_id	AC4
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL A 504

Chain	Residue
A	TYR323
A	LEU325
A	GLY327
A	CYS328
A	ASP329
A	VAL332
A	HOH760

---

site_id	AC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE GOL A 505

Chain	Residue
A	ARG162
A	ALA204
A	ASP207
A	LYS284

---

site_id	AC6
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL A 506

Chain	Residue
A	LYS393
A	TYR421
A	TYR427
A	ASP428
A	ASP429
A	SER430

---

site_id	AC7
Number of Residues	5
Details	BINDING SITE FOR RESIDUE GOL A 507

Chain	Residue
A	TRP359
A	ASN360
A	ASP361
A	LYS362
A	HOH711

---

site_id	AC8
Number of Residues	3
Details	BINDING SITE FOR RESIDUE GOL A 508

Chain	Residue
A	TYR240
A	GLY480
A	HOH745

---

site_id	AC9
Number of Residues	3
Details	BINDING SITE FOR RESIDUE GOL A 509

Chain	Residue
A	GLN394
A	MET434
A	ARG439

---

site_id	BC1
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL A 510

Chain	Residue
A	PHE190
A	ASP215
A	LEU216
A	TRP220
A	GLU221
A	LEU265
A	HOH657

---

site_id	BC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 A 511

Chain	Residue
A	LYS386
A	ARG420
A	TYR427

---

site_id	BC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 A 512

Chain	Residue
A	ARG89
A	ALA176
A	PRO178
A	GOL501
A	HOH659

---

site_id	BC4
Number of Residues	1
Details	BINDING SITE FOR RESIDUE PO3 A 513

Chain	Residue
A	ARG194

---

site_id	BC5
Number of Residues	18
Details	BINDING SITE FOR RESIDUE ST7 A 514

Chain	Residue
A	TYR10
A	PHE12
A	TRP97
A	ASP142
A	GLU144
A	MET212
A	TYR214
A	ASP215
A	PRO219
A	TRP220
A	TYR292
A	ARG294
A	GLY314
A	ARG338
A	ILE339
A	TRP403
A	HOH690
A	HOH704

---

Functional Information from PROSITE/UniProt

site_id	PS01095
Number of Residues	9
Details	GH18_1 Glycosyl hydrolases family 18 (GH18) active site signature. FDGVDIDwE

Chain	Residue	Details
A	PHE136-GLU144

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	383
Details	Domain: {"description":"GH18","evidences":[{"source":"PROSITE-ProRule","id":"PRU01258","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	60
Details	Domain: {"description":"Chitin-binding type-3"}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	1
Details	Active site: {"description":"Proton donor","evidences":[{"source":"PROSITE-ProRule","id":"PRU01258","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	9
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU01258","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---