3WCB

The complex structure of TcSQS with ligand, BPH1237

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0008610	biological_process	lipid biosynthetic process
A	0009058	biological_process	biosynthetic process
A	0016765	molecular_function	transferase activity, transferring alkyl or aryl (other than methyl) groups
A	0045338	biological_process	farnesyl diphosphate metabolic process
A	0051996	molecular_function	squalene synthase [NAD(P)H] activity
B	0008610	biological_process	lipid biosynthetic process
B	0009058	biological_process	biosynthetic process
B	0016765	molecular_function	transferase activity, transferring alkyl or aryl (other than methyl) groups
B	0045338	biological_process	farnesyl diphosphate metabolic process
B	0051996	molecular_function	squalene synthase [NAD(P)H] activity
C	0008610	biological_process	lipid biosynthetic process
C	0009058	biological_process	biosynthetic process
C	0016765	molecular_function	transferase activity, transferring alkyl or aryl (other than methyl) groups
C	0045338	biological_process	farnesyl diphosphate metabolic process
C	0051996	molecular_function	squalene synthase [NAD(P)H] activity
D	0008610	biological_process	lipid biosynthetic process
D	0009058	biological_process	biosynthetic process
D	0016765	molecular_function	transferase activity, transferring alkyl or aryl (other than methyl) groups
D	0045338	biological_process	farnesyl diphosphate metabolic process
D	0051996	molecular_function	squalene synthase [NAD(P)H] activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	BINDING SITE FOR RESIDUE 8PH A 401

Chain	Residue
A	SER42
A	SER44
A	PHE45
A	TYR64
A	ARG68
A	MET199
A	LEU203

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site_id	AC2
Number of Residues	8
Details	BINDING SITE FOR RESIDUE 8PH B 401

Chain	Residue
B	ARG43
B	SER44
B	PHE45
B	TYR64
B	ARG68
B	ASN207
B	VAL41
B	SER42

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site_id	AC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE 8PH C 401

Chain	Residue
C	LYS309
C	HOH516
C	HOH531

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site_id	AC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE 8PH D 401

Chain	Residue
D	VAL41
D	SER42
D	SER44
D	TYR64
D	ARG68
D	HOH542

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Functional Information from PROSITE/UniProt

site_id	PS01044
Number of Residues	16
Details	SQUALEN_PHYTOEN_SYN_1 Squalene and phytoene synthases signature 1. YChyVAGLVGhgLtlL

Chain	Residue	Details
A	TYR163-LEU178

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site_id	PS01045
Number of Residues	28
Details	SQUALEN_PHYTOEN_SYN_2 Squalene and phytoene synthases signature 2. MGlflQkt.NIiRDFyeDicevpp.RvFwP

Chain	Residue	Details
A	MET199-PRO226

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