Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004672 | molecular_function | protein kinase activity |
| A | 0004674 | molecular_function | protein serine/threonine kinase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006468 | biological_process | protein phosphorylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE NIO A 401 |
| Chain | Residue |
| A | VAL66 |
| A | LYS68 |
| A | PHE113 |
| A | MET163 |
| A | ASP175 |
| A | HOH510 |
| A | HOH657 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO A 402 |
| Chain | Residue |
| A | PHE54 |
| A | GLU296 |
| A | PRO322 |
| A | LEU41 |
| A | VAL42 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO A 403 |
| Chain | Residue |
| A | ASN117 |
| A | ASN118 |
| A | THR119 |
| A | ILE164 |
| A | ASP165 |
| A | HIS166 |
| A | GLU167 |
| site_id | AC4 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE EDO A 404 |
| Chain | Residue |
| A | ASN118 |
| A | THR119 |
| A | ASP120 |
| A | PHE121 |
| A | PRO159 |
| A | VAL162 |
| A | MET163 |
| A | ILE164 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO A 405 |
| Chain | Residue |
| A | PHE232 |
| A | PHE284 |
| A | HOH539 |
| A | HOH558 |
| A | HOH783 |
| site_id | AC6 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE EDO A 406 |
| Chain | Residue |
| A | VAL248 |
| A | LEU249 |
| A | ARG278 |
| A | LYS279 |
| A | TRP281 |
| A | ASP302 |
| A | HOH582 |
| A | HOH758 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO A 407 |
| Chain | Residue |
| A | THR17 |
| A | HIS168 |
| A | HIS183 |
| A | PRO184 |
| A | HOH645 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO A 408 |
| Chain | Residue |
| A | ARG8 |
| A | HIS168 |
| A | LYS170 |
| A | PRO184 |
| A | HOH612 |
| A | HOH793 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO A 409 |
| Chain | Residue |
| A | GLN36 |
| A | TYR39 |
| A | VAL101 |
| A | ASP103 |
| site_id | BC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO A 410 |
| Chain | Residue |
| A | THR127 |
| A | ASP132 |
| A | HIS166 |
| A | HOH712 |
| A | HOH773 |
| site_id | BC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO A 411 |
| Chain | Residue |
| A | TYR131 |
| A | ASP132 |
| A | PHE135 |
| A | TYR136 |
| A | HIS166 |
| A | ARG169 |
| site_id | BC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO A 412 |
| Chain | Residue |
| A | ARG191 |
| A | VAL192 |
| A | ALA193 |
| A | LYS198 |
| A | HOH652 |
| site_id | BC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO A 413 |
| Chain | Residue |
| A | ARG80 |
| A | LEU178 |
| A | MET334 |
| site_id | BC5 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE EDO A 414 |
| Chain | Residue |
| A | LEU41 |
| A | ILE69 |
| A | ASP103 |
| A | PRO104 |
| A | VAL105 |
| A | GLU320 |
| A | EDO415 |
| A | HOH755 |
| site_id | BC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO A 415 |
| Chain | Residue |
| A | GLN36 |
| A | TYR39 |
| A | GLN40 |
| A | GLU320 |
| A | TYR325 |
| A | EDO414 |
| site_id | BC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO A 416 |
| Chain | Residue |
| A | ASP130 |
| A | TYR131 |
| A | ARG134 |
| A | THR326 |
| A | HOH564 |
| site_id | BC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO A 417 |
| Chain | Residue |
| A | HIS236 |
| A | ASP237 |
| A | ASP259 |
| A | HOH771 |
| site_id | BC9 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE EDO A 418 |
| Chain | Residue |
| A | TYR211 |
| A | SER212 |
| A | MET215 |
| A | ALA315 |
| A | HOH507 |
| A | HOH515 |
| A | HOH524 |
| A | VAL11 |
| A | HIS148 |
| site_id | CC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO A 419 |
| Chain | Residue |
| A | ARG280 |
| A | GLU282 |
| A | HOH681 |
| A | HOH714 |
| A | HOH731 |
| site_id | CC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO A 420 |
| Chain | Residue |
| A | ARG280 |
| A | TRP281 |
| A | GLU282 |
| A | LEU298 |
| A | ASP302 |
| A | HOH758 |
Functional Information from PROSITE/UniProt
| site_id | PS00107 |
| Number of Residues | 24 |
| Details | PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. LGRGKYSEVFeAinitnnek..........VVVK |
| Chain | Residue | Details |
| A | LEU45-LYS68 | |
| site_id | PS00108 |
| Number of Residues | 13 |
| Details | PROTEIN_KINASE_ST Serine/Threonine protein kinases active-site signature. ImHrDVKphNVMI |
| Chain | Residue | Details |
| A | ILE152-ILE164 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 285 |
| Details | Domain: {"description":"Protein kinase","evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 5 |
| Details | Region: {"description":"Interaction with beta subunit","evidences":[{"evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Proton acceptor"} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 9 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"}]} |
