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3W9T

pore-forming CEL-III

Functional Information from GO Data
ChainGOidnamespacecontents
A0000287molecular_functionmagnesium ion binding
A0001906biological_processcell killing
A0004653molecular_functionpolypeptide N-acetylgalactosaminyltransferase activity
A0005509molecular_functioncalcium ion binding
A0005534molecular_functiongalactose binding
A0005576cellular_componentextracellular region
A0005615cellular_componentextracellular space
A0005794cellular_componentGolgi apparatus
A0006493biological_processprotein O-linked glycosylation
A0019731biological_processantibacterial humoral response
A0030246molecular_functioncarbohydrate binding
A0030395molecular_functionlactose binding
A0031640biological_processkilling of cells of another organism
A0034120biological_processpositive regulation of erythrocyte aggregation
A0042742biological_processdefense response to bacterium
A0042806molecular_functionfucose binding
A0044179biological_processhemolysis in another organism
A0046871molecular_functionN-acetylgalactosamine binding
A0046872molecular_functionmetal ion binding
A0050829biological_processdefense response to Gram-negative bacterium
A0050830biological_processdefense response to Gram-positive bacterium
A0051260biological_processprotein homooligomerization
A0051673biological_processdisruption of plasma membrane integrity in another organism
A1903777molecular_functionmelibiose binding
B0000287molecular_functionmagnesium ion binding
B0001906biological_processcell killing
B0004653molecular_functionpolypeptide N-acetylgalactosaminyltransferase activity
B0005509molecular_functioncalcium ion binding
B0005534molecular_functiongalactose binding
B0005576cellular_componentextracellular region
B0005615cellular_componentextracellular space
B0005794cellular_componentGolgi apparatus
B0006493biological_processprotein O-linked glycosylation
B0019731biological_processantibacterial humoral response
B0030246molecular_functioncarbohydrate binding
B0030395molecular_functionlactose binding
B0031640biological_processkilling of cells of another organism
B0034120biological_processpositive regulation of erythrocyte aggregation
B0042742biological_processdefense response to bacterium
B0042806molecular_functionfucose binding
B0044179biological_processhemolysis in another organism
B0046871molecular_functionN-acetylgalactosamine binding
B0046872molecular_functionmetal ion binding
B0050829biological_processdefense response to Gram-negative bacterium
B0050830biological_processdefense response to Gram-positive bacterium
B0051260biological_processprotein homooligomerization
B0051673biological_processdisruption of plasma membrane integrity in another organism
B1903777molecular_functionmelibiose binding
C0000287molecular_functionmagnesium ion binding
C0001906biological_processcell killing
C0004653molecular_functionpolypeptide N-acetylgalactosaminyltransferase activity
C0005509molecular_functioncalcium ion binding
C0005534molecular_functiongalactose binding
C0005576cellular_componentextracellular region
C0005615cellular_componentextracellular space
C0005794cellular_componentGolgi apparatus
C0006493biological_processprotein O-linked glycosylation
C0019731biological_processantibacterial humoral response
C0030246molecular_functioncarbohydrate binding
C0030395molecular_functionlactose binding
C0031640biological_processkilling of cells of another organism
C0034120biological_processpositive regulation of erythrocyte aggregation
C0042742biological_processdefense response to bacterium
C0042806molecular_functionfucose binding
C0044179biological_processhemolysis in another organism
C0046871molecular_functionN-acetylgalactosamine binding
C0046872molecular_functionmetal ion binding
C0050829biological_processdefense response to Gram-negative bacterium
C0050830biological_processdefense response to Gram-positive bacterium
C0051260biological_processprotein homooligomerization
C0051673biological_processdisruption of plasma membrane integrity in another organism
C1903777molecular_functionmelibiose binding
D0000287molecular_functionmagnesium ion binding
D0001906biological_processcell killing
D0004653molecular_functionpolypeptide N-acetylgalactosaminyltransferase activity
D0005509molecular_functioncalcium ion binding
D0005534molecular_functiongalactose binding
D0005576cellular_componentextracellular region
D0005615cellular_componentextracellular space
D0005794cellular_componentGolgi apparatus
D0006493biological_processprotein O-linked glycosylation
D0019731biological_processantibacterial humoral response
D0030246molecular_functioncarbohydrate binding
D0030395molecular_functionlactose binding
D0031640biological_processkilling of cells of another organism
D0034120biological_processpositive regulation of erythrocyte aggregation
D0042742biological_processdefense response to bacterium
D0042806molecular_functionfucose binding
D0044179biological_processhemolysis in another organism
D0046871molecular_functionN-acetylgalactosamine binding
D0046872molecular_functionmetal ion binding
D0050829biological_processdefense response to Gram-negative bacterium
D0050830biological_processdefense response to Gram-positive bacterium
D0051260biological_processprotein homooligomerization
D0051673biological_processdisruption of plasma membrane integrity in another organism
D1903777molecular_functionmelibiose binding
E0000287molecular_functionmagnesium ion binding
E0001906biological_processcell killing
E0004653molecular_functionpolypeptide N-acetylgalactosaminyltransferase activity
E0005509molecular_functioncalcium ion binding
E0005534molecular_functiongalactose binding
E0005576cellular_componentextracellular region
E0005615cellular_componentextracellular space
E0005794cellular_componentGolgi apparatus
E0006493biological_processprotein O-linked glycosylation
E0019731biological_processantibacterial humoral response
E0030246molecular_functioncarbohydrate binding
E0030395molecular_functionlactose binding
E0031640biological_processkilling of cells of another organism
E0034120biological_processpositive regulation of erythrocyte aggregation
E0042742biological_processdefense response to bacterium
E0042806molecular_functionfucose binding
E0044179biological_processhemolysis in another organism
E0046871molecular_functionN-acetylgalactosamine binding
E0046872molecular_functionmetal ion binding
E0050829biological_processdefense response to Gram-negative bacterium
E0050830biological_processdefense response to Gram-positive bacterium
E0051260biological_processprotein homooligomerization
E0051673biological_processdisruption of plasma membrane integrity in another organism
E1903777molecular_functionmelibiose binding
F0000287molecular_functionmagnesium ion binding
F0001906biological_processcell killing
F0004653molecular_functionpolypeptide N-acetylgalactosaminyltransferase activity
F0005509molecular_functioncalcium ion binding
F0005534molecular_functiongalactose binding
F0005576cellular_componentextracellular region
F0005615cellular_componentextracellular space
F0005794cellular_componentGolgi apparatus
F0006493biological_processprotein O-linked glycosylation
F0019731biological_processantibacterial humoral response
F0030246molecular_functioncarbohydrate binding
F0030395molecular_functionlactose binding
F0031640biological_processkilling of cells of another organism
F0034120biological_processpositive regulation of erythrocyte aggregation
F0042742biological_processdefense response to bacterium
F0042806molecular_functionfucose binding
F0044179biological_processhemolysis in another organism
F0046871molecular_functionN-acetylgalactosamine binding
F0046872molecular_functionmetal ion binding
F0050829biological_processdefense response to Gram-negative bacterium
F0050830biological_processdefense response to Gram-positive bacterium
F0051260biological_processprotein homooligomerization
F0051673biological_processdisruption of plasma membrane integrity in another organism
F1903777molecular_functionmelibiose binding
G0000287molecular_functionmagnesium ion binding
G0001906biological_processcell killing
G0004653molecular_functionpolypeptide N-acetylgalactosaminyltransferase activity
G0005509molecular_functioncalcium ion binding
G0005534molecular_functiongalactose binding
G0005576cellular_componentextracellular region
G0005615cellular_componentextracellular space
G0005794cellular_componentGolgi apparatus
G0006493biological_processprotein O-linked glycosylation
G0019731biological_processantibacterial humoral response
G0030246molecular_functioncarbohydrate binding
G0030395molecular_functionlactose binding
G0031640biological_processkilling of cells of another organism
G0034120biological_processpositive regulation of erythrocyte aggregation
G0042742biological_processdefense response to bacterium
G0042806molecular_functionfucose binding
G0044179biological_processhemolysis in another organism
G0046871molecular_functionN-acetylgalactosamine binding
G0046872molecular_functionmetal ion binding
G0050829biological_processdefense response to Gram-negative bacterium
G0050830biological_processdefense response to Gram-positive bacterium
G0051260biological_processprotein homooligomerization
G0051673biological_processdisruption of plasma membrane integrity in another organism
G1903777molecular_functionmelibiose binding
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues14
DetailsBINDING: BINDING => ECO:0000269|PubMed:17977832, ECO:0007744|PDB:2Z48
ChainResidueDetails
AASP9
FVAL107
EASP9
EVAL107
DASP9
DVAL107
AVAL107
CASP9
CVAL107
GASP9
GVAL107
BASP9
BVAL107
FASP9

site_idSWS_FT_FI2
Number of Residues210
DetailsBINDING: BINDING => ECO:0000269|PubMed:15194688, ECO:0000269|PubMed:17977832, ECO:0000269|PubMed:24652284, ECO:0007744|PDB:1VCL, ECO:0007744|PDB:2Z48, ECO:0007744|PDB:2Z49, ECO:0007744|PDB:3W9T
ChainResidueDetails
AASP23
AILE122
BILE122
BGLY124
BILE131
BASP141
BASP168
BVAL169
BGLY171
BASN177
BVAL178
BASP188
AGLY124
BASP209
BVAL210
BGLY212
BASN218
BVAL219
BASP229
BASP256
BVAL257
BGLY259
BASP265
AILE131
BVAL266
FASP23
FILE24
FGLY26
FASN32
FILE33
FASP43
FASN72
FVAL73
FASP121
AASP141
FILE122
FGLY124
FILE131
FASP141
FASP168
FVAL169
FGLY171
FASN177
FVAL178
FASP188
AASP168
FASP209
FVAL210
FGLY212
FASN218
FVAL219
FASP229
FASP256
FVAL257
FGLY259
FASP265
AVAL169
FVAL266
EASP23
EILE24
EGLY26
EASN32
EILE33
EASP43
EASN72
EVAL73
EASP121
AGLY171
EILE122
EGLY124
EILE131
EASP141
EASP168
EVAL169
EGLY171
EASN177
EVAL178
EASP188
AASN177
EASP209
EVAL210
EGLY212
EASN218
EVAL219
EASP229
EASP256
EVAL257
EGLY259
EASP265
AVAL178
EVAL266
DASP23
DILE24
DGLY26
DASN32
DILE33
DASP43
DASN72
DVAL73
DASP121
AASP188
DILE122
DGLY124
DILE131
DASP141
DASP168
DVAL169
DGLY171
DASN177
DVAL178
DASP188
AILE24
AASP209
DASP209
DVAL210
DGLY212
DASN218
DVAL219
DASP229
DASP256
DVAL257
DGLY259
DASP265
AVAL210
DVAL266
AGLY212
AASN218
AVAL219
AASP229
AASP256
AVAL257
AGLY259
AASP265
AGLY26
AVAL266
CASP23
CILE24
CGLY26
CASN32
CILE33
CASP43
CASN72
CVAL73
CASP121
AASN32
CILE122
CGLY124
CILE131
CASP141
CASP168
CVAL169
CGLY171
CASN177
CVAL178
CASP188
AILE33
CASP209
CVAL210
CGLY212
CASN218
CVAL219
CASP229
CASP256
CVAL257
CGLY259
CASP265
AASP43
CVAL266
GASP23
GILE24
GGLY26
GASN32
GILE33
GASP43
GASN72
GVAL73
GASP121
AASN72
GILE122
GGLY124
GILE131
GASP141
GASP168
GVAL169
GGLY171
GASN177
GVAL178
GASP188
AVAL73
GASP209
GVAL210
GGLY212
GASN218
GVAL219
GASP229
GASP256
GVAL257
GGLY259
GASP265
AASP121
GVAL266
BASP23
BILE24
BGLY26
BASN32
BILE33
BASP43
BASN72
BVAL73
BASP121

site_idSWS_FT_FI3
Number of Residues21
DetailsBINDING: BINDING => ECO:0000269|PubMed:17977832, ECO:0000269|PubMed:24652284, ECO:0007744|PDB:2Z48, ECO:0007744|PDB:2Z49, ECO:0007744|PDB:3W9T
ChainResidueDetails
AASP39
BASP39
BTRP269
BASP276
FASP39
FTRP269
FASP276
EASP39
ETRP269
EASP276
DASP39
ATRP269
DTRP269
DASP276
AASP276
CASP39
CTRP269
CASP276
GASP39
GTRP269
GASP276

site_idSWS_FT_FI4
Number of Residues21
DetailsBINDING: BINDING => ECO:0000269|PubMed:17977832, ECO:0000269|PubMed:24652284, ECO:0007744|PDB:2Z49, ECO:0007744|PDB:3W9T
ChainResidueDetails
ATYR134
BTYR134
BTYR181
BTYR222
FTYR134
FTYR181
FTYR222
ETYR134
ETYR181
ETYR222
DTYR134
ATYR181
DTYR181
DTYR222
ATYR222
CTYR134
CTYR181
CTYR222
GTYR134
GTYR181
GTYR222

site_idSWS_FT_FI5
Number of Residues7
DetailsMOD_RES: Pyrrolidone carboxylic acid => ECO:0000269|PubMed:10561549, ECO:0000269|PubMed:15194688
ChainResidueDetails
APCA1
CPCA1
GPCA1
BPCA1
FPCA1
EPCA1
DPCA1

227111

PDB entries from 2024-11-06

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