Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

3W6X

Yeast N-acetyltransferase Mpr1 in complex with CHOP

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005634	cellular_component	nucleus
A	0005737	cellular_component	cytoplasm
A	0005739	cellular_component	mitochondrion
A	0005829	cellular_component	cytosol
A	0006526	biological_process	L-arginine biosynthetic process
A	0006562	biological_process	L-proline catabolic process
A	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
A	0046941	molecular_function	azetidine-2-carboxylic acid acetyltransferase activity
B	0005634	cellular_component	nucleus
B	0005737	cellular_component	cytoplasm
B	0005739	cellular_component	mitochondrion
B	0005829	cellular_component	cytosol
B	0006526	biological_process	L-arginine biosynthetic process
B	0006562	biological_process	L-proline catabolic process
B	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
B	0046941	molecular_function	azetidine-2-carboxylic acid acetyltransferase activity
C	0005634	cellular_component	nucleus
C	0005737	cellular_component	cytoplasm
C	0005739	cellular_component	mitochondrion
C	0005829	cellular_component	cytosol
C	0006526	biological_process	L-arginine biosynthetic process
C	0006562	biological_process	L-proline catabolic process
C	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
C	0046941	molecular_function	azetidine-2-carboxylic acid acetyltransferase activity
D	0005634	cellular_component	nucleus
D	0005737	cellular_component	cytoplasm
D	0005739	cellular_component	mitochondrion
D	0005829	cellular_component	cytosol
D	0006526	biological_process	L-arginine biosynthetic process
D	0006562	biological_process	L-proline catabolic process
D	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
D	0046941	molecular_function	azetidine-2-carboxylic acid acetyltransferase activity
E	0005634	cellular_component	nucleus
E	0005737	cellular_component	cytoplasm
E	0005739	cellular_component	mitochondrion
E	0005829	cellular_component	cytosol
E	0006526	biological_process	L-arginine biosynthetic process
E	0006562	biological_process	L-proline catabolic process
E	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
E	0046941	molecular_function	azetidine-2-carboxylic acid acetyltransferase activity
F	0005634	cellular_component	nucleus
F	0005737	cellular_component	cytoplasm
F	0005739	cellular_component	mitochondrion
F	0005829	cellular_component	cytosol
F	0006526	biological_process	L-arginine biosynthetic process
F	0006562	biological_process	L-proline catabolic process
F	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
F	0046941	molecular_function	azetidine-2-carboxylic acid acetyltransferase activity
G	0005634	cellular_component	nucleus
G	0005737	cellular_component	cytoplasm
G	0005739	cellular_component	mitochondrion
G	0005829	cellular_component	cytosol
G	0006526	biological_process	L-arginine biosynthetic process
G	0006562	biological_process	L-proline catabolic process
G	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
G	0046941	molecular_function	azetidine-2-carboxylic acid acetyltransferase activity
H	0005634	cellular_component	nucleus
H	0005737	cellular_component	cytoplasm
H	0005739	cellular_component	mitochondrion
H	0005829	cellular_component	cytosol
H	0006526	biological_process	L-arginine biosynthetic process
H	0006562	biological_process	L-proline catabolic process
H	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
H	0046941	molecular_function	azetidine-2-carboxylic acid acetyltransferase activity
I	0005634	cellular_component	nucleus
I	0005737	cellular_component	cytoplasm
I	0005739	cellular_component	mitochondrion
I	0005829	cellular_component	cytosol
I	0006526	biological_process	L-arginine biosynthetic process
I	0006562	biological_process	L-proline catabolic process
I	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
I	0046941	molecular_function	azetidine-2-carboxylic acid acetyltransferase activity
J	0005634	cellular_component	nucleus
J	0005737	cellular_component	cytoplasm
J	0005739	cellular_component	mitochondrion
J	0005829	cellular_component	cytosol
J	0006526	biological_process	L-arginine biosynthetic process
J	0006562	biological_process	L-proline catabolic process
J	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
J	0046941	molecular_function	azetidine-2-carboxylic acid acetyltransferase activity
K	0005634	cellular_component	nucleus
K	0005737	cellular_component	cytoplasm
K	0005739	cellular_component	mitochondrion
K	0005829	cellular_component	cytosol
K	0006526	biological_process	L-arginine biosynthetic process
K	0006562	biological_process	L-proline catabolic process
K	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
K	0046941	molecular_function	azetidine-2-carboxylic acid acetyltransferase activity
L	0005634	cellular_component	nucleus
L	0005737	cellular_component	cytoplasm
L	0005739	cellular_component	mitochondrion
L	0005829	cellular_component	cytosol
L	0006526	biological_process	L-arginine biosynthetic process
L	0006562	biological_process	L-proline catabolic process
L	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
L	0046941	molecular_function	azetidine-2-carboxylic acid acetyltransferase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	8
Details	BINDING SITE FOR RESIDUE HZP A 301

Chain	Residue
A	TYR75
A	PRO76
A	TYR121
A	ASN135
A	ALA136
A	PHE171
A	ASN172
A	LEU173

site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE P6G A 302

Chain	Residue
A	HIS92
A	TYR121
A	LYS123
A	TYR89

site_id	AC3
Number of Residues	9
Details	BINDING SITE FOR RESIDUE HZP B 301

Chain	Residue
B	TYR75
B	TYR121
B	ASN135
B	ALA136
B	PHE171
B	ASN172
B	LEU173
B	HOH406
B	HOH434

site_id	AC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE P6G B 302

Chain	Residue
B	TYR89
B	HIS92
B	TYR121
B	LYS123
B	ASN135

site_id	AC5
Number of Residues	9
Details	BINDING SITE FOR RESIDUE HZP C 301

Chain	Residue
C	TYR75
C	TYR121
C	ASN135
C	ALA136
C	PHE171
C	ASN172
C	LEU173
C	HOH421
C	HOH435

site_id	AC6
Number of Residues	7
Details	BINDING SITE FOR RESIDUE P6G C 302

Chain	Residue
C	TYR89
C	HIS92
C	TYR121
C	LYS123
C	PRO124
C	TYR126
C	ASN135

site_id	AC7
Number of Residues	5
Details	BINDING SITE FOR RESIDUE P6G D 301

Chain	Residue
D	TYR89
D	HIS92
D	TYR121
D	LYS123
D	ASN135

site_id	AC8
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CL D 302

Chain	Residue
C	PRO128
D	LEU78
D	HIS79

site_id	AC9
Number of Residues	7
Details	BINDING SITE FOR RESIDUE P6G E 301

Chain	Residue
E	TYR89
E	HIS92
E	TYR121
E	LYS123
E	PRO124
E	ASN125
E	ASN135

site_id	BC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CL E 302

Chain	Residue
E	LEU78
E	HIS79
F	PRO128

site_id	BC2
Number of Residues	7
Details	BINDING SITE FOR RESIDUE HZP F 301

Chain	Residue
F	PRO76
F	ASN135
F	ALA136
F	PHE171
F	ASN172
F	LEU173
F	HOH445

site_id	BC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE P6G F 302

Chain	Residue
F	TYR89
F	HIS92
F	TYR121
F	LYS123
F	PRO124

site_id	BC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE P6G G 301

Chain	Residue
G	TYR89
G	HIS92
G	LYS123
G	ASN125
G	ASN135

site_id	BC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CL G 302

Chain	Residue
G	LEU78
G	HIS79
H	PRO128

site_id	BC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE P6G H 301

Chain	Residue
H	TYR89
H	HIS92
H	TYR121
H	LYS123
H	ASN135

site_id	BC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CL H 302

Chain	Residue
G	PRO128
H	LEU78
H	HIS79
H	HOH438

site_id	BC8
Number of Residues	5
Details	BINDING SITE FOR RESIDUE P6G I 301

Chain	Residue
I	TYR89
I	HIS92
I	TYR121
I	LYS123
I	ASN125

site_id	BC9
Number of Residues	6
Details	BINDING SITE FOR RESIDUE P6G J 301

Chain	Residue
J	ASN135
J	TYR89
J	HIS92
J	TYR121
J	LYS123
J	PRO124

site_id	CC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE P6G K 301

Chain	Residue
K	TYR89
K	HIS92
K	TYR121
K	LYS123
K	PRO124
K	ASN135

site_id	CC2
Number of Residues	8
Details	BINDING SITE FOR RESIDUE P6G L 301

Chain	Residue
L	TYR89
L	HIS92
L	TYR121
L	LYS123
L	PRO124
L	TYR126
L	ASN135
L	ASN172

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1848
Details	Domain: {"description":"N-acetyltransferase","evidences":[{"source":"PROSITE-ProRule","id":"PRU00532","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	24
Details	Binding site: {"evidences":[{"source":"PubMed","id":"23818613","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3W6X","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI3
Number of Residues	60
Details	Binding site: {"evidences":[{"source":"PubMed","id":"11555637","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)