3VYV
Crystal structure of subtilisin NAT at 1.36
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004252 | molecular_function | serine-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| A | 0008236 | molecular_function | serine-type peptidase activity |
| B | 0004252 | molecular_function | serine-type endopeptidase activity |
| B | 0006508 | biological_process | proteolysis |
| B | 0008236 | molecular_function | serine-type peptidase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL A 301 |
| Chain | Residue |
| A | ASN118 |
| A | MET119 |
| A | SER145 |
| A | GLY146 |
| A | HOH443 |
| A | HOH564 |
| A | HOH603 |
| A | HOH609 |
| site_id | AC2 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE GOL A 302 |
| Chain | Residue |
| A | SER49 |
| A | THR55 |
| A | THR253 |
| A | ALA254 |
| A | THR255 |
| A | ALA272 |
| A | HOH451 |
| A | HOH562 |
| A | HOH563 |
| A | HOH565 |
| A | ALA48 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 303 |
| Chain | Residue |
| A | GLN2 |
| A | ASP41 |
| A | LEU75 |
| A | ASN77 |
| A | ILE79 |
| A | VAL81 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 304 |
| Chain | Residue |
| A | ALA169 |
| A | TYR171 |
| A | THR174 |
| A | GLU195 |
| A | ASP197 |
| A | HOH470 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA B 301 |
| Chain | Residue |
| B | GLN2 |
| B | ASP41 |
| B | LEU75 |
| B | ASN77 |
| B | ILE79 |
| B | VAL81 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA B 302 |
| Chain | Residue |
| B | ALA169 |
| B | TYR171 |
| B | THR174 |
| B | GLU195 |
| B | ASP197 |
| B | HOH481 |
Functional Information from PROSITE/UniProt
| site_id | PS00136 |
| Number of Residues | 12 |
| Details | SUBTILASE_ASP Serine proteases, subtilase family, aspartic acid active site. VAVIDSGIdssH |
| Chain | Residue | Details |
| A | VAL28-HIS39 |
| site_id | PS00137 |
| Number of Residues | 11 |
| Details | SUBTILASE_HIS Serine proteases, subtilase family, histidine active site. HGThVAGtIAA |
| Chain | Residue | Details |
| A | HIS64-ALA74 |
| site_id | PS00138 |
| Number of Residues | 11 |
| Details | SUBTILASE_SER Serine proteases, subtilase family, serine active site. GTSmAtPhVAG |
| Chain | Residue | Details |
| A | GLY219-GLY229 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | Active site: {"description":"Charge relay system","evidences":[{"source":"PROSITE-ProRule","id":"PRU01240","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Charge relay system","evidences":[{"source":"PROSITE-ProRule","id":"PRU01240","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"24121331","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 16 |
| Details | Binding site: {"evidences":[{"source":"PDB","id":"3VYV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4DWW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5GL8","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PDB","id":"4DWW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5GL8","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
