3VYP
Crystal structure of Mycobacterium tuberculosis L,D-transpeptidase LdtMt2-N140 adduct with meropenem
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL A 501 |
| Chain | Residue |
| A | GLU213 |
| A | HIS214 |
| A | PHE215 |
| A | ILE291 |
| A | HOH765 |
| A | HOH778 |
| site_id | AC2 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE MXR A 502 |
| Chain | Residue |
| A | SER331 |
| A | GLY332 |
| A | VAL333 |
| A | HIS352 |
| A | GLY353 |
| A | CYS354 |
| A | HOH760 |
| A | HOH929 |
| B | ASP367 |
| B | HOH670 |
| A | MET303 |
| A | TYR308 |
| A | TYR318 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL B 501 |
| Chain | Residue |
| B | HIS214 |
| B | PHE215 |
| B | ILE291 |
| B | HOH780 |
| B | HOH895 |
| site_id | AC4 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE MXR B 502 |
| Chain | Residue |
| A | GLN363 |
| A | HOH848 |
| B | MET303 |
| B | TYR308 |
| B | TYR318 |
| B | SER331 |
| B | GLY332 |
| B | HIS352 |
| B | GLY353 |
| B | CYS354 |
| B | HOH965 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 250 |
| Details | Domain: {"description":"L,D-TPase catalytic","evidences":[{"source":"PROSITE-ProRule","id":"PRU01373","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton donor/acceptor","evidences":[{"source":"PROSITE-ProRule","id":"PRU01373","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"23103390","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Nucleophile","evidences":[{"source":"PROSITE-ProRule","id":"PRU01373","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"23103390","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 6 |
| Details | Binding site: {} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | Site: {"description":"Binds to carbapenem drug (covalent)","evidences":[{"evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
