Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

3VR4

Crystal structure of Enterococcus hirae V1-ATPase [eV1]

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005515	molecular_function	protein binding
A	0005524	molecular_function	ATP binding
A	0006814	biological_process	sodium ion transport
A	0035725	biological_process	sodium ion transmembrane transport
A	0042777	biological_process	proton motive force-driven plasma membrane ATP synthesis
A	0045259	cellular_component	proton-transporting ATP synthase complex
A	0046034	biological_process	ATP metabolic process
A	0046932	molecular_function	sodium-transporting ATP synthase activity, rotational mechanism
A	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
A	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
A	0046962	molecular_function	sodium-transporting ATPase activity, rotational mechanism
A	1902600	biological_process	proton transmembrane transport
B	0005515	molecular_function	protein binding
B	0005524	molecular_function	ATP binding
B	0006814	biological_process	sodium ion transport
B	0035725	biological_process	sodium ion transmembrane transport
B	0042777	biological_process	proton motive force-driven plasma membrane ATP synthesis
B	0045259	cellular_component	proton-transporting ATP synthase complex
B	0046034	biological_process	ATP metabolic process
B	0046932	molecular_function	sodium-transporting ATP synthase activity, rotational mechanism
B	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
B	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
B	0046962	molecular_function	sodium-transporting ATPase activity, rotational mechanism
B	1902600	biological_process	proton transmembrane transport
C	0005515	molecular_function	protein binding
C	0005524	molecular_function	ATP binding
C	0006814	biological_process	sodium ion transport
C	0035725	biological_process	sodium ion transmembrane transport
C	0042777	biological_process	proton motive force-driven plasma membrane ATP synthesis
C	0045259	cellular_component	proton-transporting ATP synthase complex
C	0046034	biological_process	ATP metabolic process
C	0046932	molecular_function	sodium-transporting ATP synthase activity, rotational mechanism
C	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
C	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
C	0046962	molecular_function	sodium-transporting ATPase activity, rotational mechanism
C	1902600	biological_process	proton transmembrane transport
D	0005515	molecular_function	protein binding
D	0005524	molecular_function	ATP binding
D	0006814	biological_process	sodium ion transport
D	0042777	biological_process	proton motive force-driven plasma membrane ATP synthesis
D	0046034	biological_process	ATP metabolic process
D	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
D	1902600	biological_process	proton transmembrane transport
E	0005515	molecular_function	protein binding
E	0005524	molecular_function	ATP binding
E	0006814	biological_process	sodium ion transport
E	0042777	biological_process	proton motive force-driven plasma membrane ATP synthesis
E	0046034	biological_process	ATP metabolic process
E	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
E	1902600	biological_process	proton transmembrane transport
F	0005515	molecular_function	protein binding
F	0005524	molecular_function	ATP binding
F	0006814	biological_process	sodium ion transport
F	0042777	biological_process	proton motive force-driven plasma membrane ATP synthesis
F	0046034	biological_process	ATP metabolic process
F	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
F	1902600	biological_process	proton transmembrane transport
G	0005524	molecular_function	ATP binding
G	0006814	biological_process	sodium ion transport
G	0042777	biological_process	proton motive force-driven plasma membrane ATP synthesis
G	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
G	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
G	1902600	biological_process	proton transmembrane transport
H	0005524	molecular_function	ATP binding
H	0006814	biological_process	sodium ion transport
H	0034220	biological_process	monoatomic ion transmembrane transport
H	0042777	biological_process	proton motive force-driven plasma membrane ATP synthesis
H	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
H	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
H	1902600	biological_process	proton transmembrane transport

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE GOL A 601

Chain	Residue
A	HIS243
A	GLN244
A	LYS247
A	PHE506

site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CL B 601

Chain	Residue
B	PHE234
B	GLY235
B	ARG262
E	ARG350

site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE GOL B 602

Chain	Residue
B	ASN429
B	TRP430
B	ILE431
B	LEU419

site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE GOL D 501

Chain	Residue
D	HIS75
D	GLN78
D	TYR108
D	HOH723

site_id	AC5
Number of Residues	2
Details	BINDING SITE FOR RESIDUE GOL D 502

Chain	Residue
D	TYR418
F	GLY293

site_id	AC6
Number of Residues	17
Details	BINDING SITE FOR RESIDUE B3P F 501

Chain	Residue
C	ASP206
C	TYR444
C	HOH809
C	HOH819
C	HOH894
F	GLU83
F	ASP176
F	ARG206
F	LYS239
F	GOL504
F	HOH619
F	HOH648
F	HOH661
F	HOH687
F	HOH710
F	HOH714
F	HOH721

site_id	AC7
Number of Residues	8
Details	BINDING SITE FOR RESIDUE B3P F 502

Chain	Residue
C	ASN271
D	GLN200
F	ASP122
F	TYR123
F	ASP125
F	GLU126
F	ARG290
F	ARG292

site_id	AC8
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL F 503

Chain	Residue
C	LYS200
C	GLN379
F	THR169
F	ASP175
F	ASP176
F	HOH819

site_id	AC9
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL F 504

Chain	Residue
C	GLU440
F	GLU238
F	GLY240
F	B3P501
F	HOH634
F	HOH757

site_id	BC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE GOL F 505

Chain	Residue
D	ASN99
F	ASP172
F	GLY359
F	LYS360
F	THR361

site_id	BC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE GOL G 301

Chain	Residue
G	THR181
G	HOH436

Functional Information from PROSITE/UniProt

site_id	PS00152
Number of Residues	10
Details	ATPASE_ALPHA_BETA ATP synthase alpha and beta subunits signature. PSINWIQSYS

Chain	Residue	Details
A	PRO426-SER435
D	PRO340-SER349

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	3
Details	BINDING: BINDING => ECO:0000250

Chain	Residue	Details
A	GLY232
B	GLY232
C	GLY232

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)