3VR1

Crystal structure analysis of the translation factor RF3

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0003924	molecular_function	GTPase activity
A	0005525	molecular_function	GTP binding
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006412	biological_process	translation
A	0006415	biological_process	translational termination
A	0006449	biological_process	regulation of translational termination
A	0016149	molecular_function	translation release factor activity, codon specific
A	0016150	molecular_function	translation release factor activity, codon nonspecific
B	0000166	molecular_function	nucleotide binding
B	0003924	molecular_function	GTPase activity
B	0005525	molecular_function	GTP binding
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0006412	biological_process	translation
B	0006415	biological_process	translational termination
B	0006449	biological_process	regulation of translational termination
B	0016149	molecular_function	translation release factor activity, codon specific
B	0016150	molecular_function	translation release factor activity, codon nonspecific
C	0000166	molecular_function	nucleotide binding
C	0003924	molecular_function	GTPase activity
C	0005525	molecular_function	GTP binding
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0006412	biological_process	translation
C	0006415	biological_process	translational termination
C	0006449	biological_process	regulation of translational termination
C	0016149	molecular_function	translation release factor activity, codon specific
C	0016150	molecular_function	translation release factor activity, codon nonspecific
D	0000166	molecular_function	nucleotide binding
D	0003924	molecular_function	GTPase activity
D	0005525	molecular_function	GTP binding
D	0005737	cellular_component	cytoplasm
D	0005829	cellular_component	cytosol
D	0006412	biological_process	translation
D	0006415	biological_process	translational termination
D	0006449	biological_process	regulation of translational termination
D	0016149	molecular_function	translation release factor activity, codon specific
D	0016150	molecular_function	translation release factor activity, codon nonspecific

Functional Information from PDB Data

site_id	AC1
Number of Residues	15
Details	BINDING SITE FOR RESIDUE G4P A 601

Chain	Residue
A	ASP22
A	LYS142
A	ASP144
A	ARG145
A	SER256
A	ALA257
A	ILE258
A	ALA23
A	GLY24
A	LYS25
A	THR26
A	THR27
A	LYS49
A	HIS91
A	ASN141

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site_id	AC2
Number of Residues	15
Details	BINDING SITE FOR RESIDUE G4P B 601

Chain	Residue
B	ASP22
B	ALA23
B	GLY24
B	LYS25
B	THR26
B	THR27
B	LYS49
B	HIS91
B	ASN141
B	LYS142
B	ASP144
B	ARG145
B	SER256
B	ALA257
B	ILE258

---

site_id	AC3
Number of Residues	15
Details	BINDING SITE FOR RESIDUE G4P C 601

Chain	Residue
C	ASP22
C	ALA23
C	GLY24
C	LYS25
C	THR26
C	THR27
C	LYS49
C	HIS91
C	ASN141
C	LYS142
C	ASP144
C	ARG145
C	SER256
C	ALA257
C	ILE258

---

site_id	AC4
Number of Residues	15
Details	BINDING SITE FOR RESIDUE G4P D 601

Chain	Residue
D	ASP22
D	ALA23
D	GLY24
D	LYS25
D	THR26
D	THR27
D	LYS49
D	HIS91
D	ASN141
D	LYS142
D	ASP144
D	ARG145
D	SER256
D	ALA257
D	ILE258

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Functional Information from PROSITE/UniProt

site_id	PS00301
Number of Residues	16
Details	G_TR_1 Translational (tr)-type guanine nucleotide-binding (G) domain signature. DWmamEReRGISVttS

Chain	Residue	Details
A	ASP57-SER72

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	56
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00072","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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