3VQI
Crystal structure of Kluyveromyces marxianus Atg5
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0000045 | biological_process | autophagosome assembly |
A | 0000422 | biological_process | autophagy of mitochondrion |
A | 0005737 | cellular_component | cytoplasm |
A | 0006501 | biological_process | C-terminal protein lipidation |
A | 0006914 | biological_process | autophagy |
A | 0006995 | biological_process | cellular response to nitrogen starvation |
A | 0015031 | biological_process | protein transport |
A | 0016020 | cellular_component | membrane |
A | 0019776 | molecular_function | Atg8-family ligase activity |
A | 0034045 | cellular_component | phagophore assembly site membrane |
A | 0034274 | cellular_component | Atg12-Atg5-Atg16 complex |
A | 0044804 | biological_process | nucleophagy |
B | 0000045 | biological_process | autophagosome assembly |
B | 0000422 | biological_process | autophagy of mitochondrion |
B | 0005737 | cellular_component | cytoplasm |
B | 0006501 | biological_process | C-terminal protein lipidation |
B | 0006914 | biological_process | autophagy |
B | 0006995 | biological_process | cellular response to nitrogen starvation |
B | 0015031 | biological_process | protein transport |
B | 0016020 | cellular_component | membrane |
B | 0019776 | molecular_function | Atg8-family ligase activity |
B | 0034045 | cellular_component | phagophore assembly site membrane |
B | 0034274 | cellular_component | Atg12-Atg5-Atg16 complex |
B | 0044804 | biological_process | nucleophagy |
C | 0000045 | biological_process | autophagosome assembly |
C | 0000422 | biological_process | autophagy of mitochondrion |
C | 0005737 | cellular_component | cytoplasm |
C | 0006501 | biological_process | C-terminal protein lipidation |
C | 0006914 | biological_process | autophagy |
C | 0006995 | biological_process | cellular response to nitrogen starvation |
C | 0015031 | biological_process | protein transport |
C | 0016020 | cellular_component | membrane |
C | 0019776 | molecular_function | Atg8-family ligase activity |
C | 0034045 | cellular_component | phagophore assembly site membrane |
C | 0034274 | cellular_component | Atg12-Atg5-Atg16 complex |
C | 0044804 | biological_process | nucleophagy |
D | 0000045 | biological_process | autophagosome assembly |
D | 0000422 | biological_process | autophagy of mitochondrion |
D | 0005737 | cellular_component | cytoplasm |
D | 0006501 | biological_process | C-terminal protein lipidation |
D | 0006914 | biological_process | autophagy |
D | 0006995 | biological_process | cellular response to nitrogen starvation |
D | 0015031 | biological_process | protein transport |
D | 0016020 | cellular_component | membrane |
D | 0019776 | molecular_function | Atg8-family ligase activity |
D | 0034045 | cellular_component | phagophore assembly site membrane |
D | 0034274 | cellular_component | Atg12-Atg5-Atg16 complex |
D | 0044804 | biological_process | nucleophagy |
E | 0000045 | biological_process | autophagosome assembly |
E | 0000422 | biological_process | autophagy of mitochondrion |
E | 0005737 | cellular_component | cytoplasm |
E | 0006501 | biological_process | C-terminal protein lipidation |
E | 0006914 | biological_process | autophagy |
E | 0006995 | biological_process | cellular response to nitrogen starvation |
E | 0015031 | biological_process | protein transport |
E | 0016020 | cellular_component | membrane |
E | 0019776 | molecular_function | Atg8-family ligase activity |
E | 0034045 | cellular_component | phagophore assembly site membrane |
E | 0034274 | cellular_component | Atg12-Atg5-Atg16 complex |
E | 0044804 | biological_process | nucleophagy |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 9 |
Details | BINDING SITE FOR RESIDUE EPE A 301 |
Chain | Residue |
A | LEU45 |
A | GLY46 |
A | TRP82 |
A | GLU83 |
A | GLN135 |
A | TYR139 |
A | HOH402 |
A | HOH410 |
D | LEU209 |
site_id | AC2 |
Number of Residues | 2 |
Details | BINDING SITE FOR RESIDUE SO4 A 302 |
Chain | Residue |
A | CYS35 |
A | HIS36 |
site_id | AC3 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE SO4 A 303 |
Chain | Residue |
A | LYS121 |
E | PRO26 |
E | ASN27 |
site_id | AC4 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE SO4 A 304 |
Chain | Residue |
A | LYS121 |
A | ARG124 |
A | HOH414 |
E | HOH411 |
site_id | AC5 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE EPE B 301 |
Chain | Residue |
B | LEU45 |
B | GLY46 |
B | TRP82 |
B | GLN135 |
B | ILE136 |
B | TYR139 |
E | LEU209 |
site_id | AC6 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE SO4 B 302 |
Chain | Residue |
A | ARG54 |
A | LYS55 |
B | SER179 |
site_id | AC7 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE SO4 B 303 |
Chain | Residue |
B | SER34 |
B | CYS35 |
B | HIS36 |
site_id | AC8 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE SO4 B 304 |
Chain | Residue |
B | ARG141 |
B | HIS142 |
B | LYS145 |
site_id | AC9 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE SO4 B 305 |
Chain | Residue |
B | LYS121 |
D | ASP21 |
D | PRO26 |
D | ASN27 |
D | HOH404 |
site_id | BC1 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE SO4 C 301 |
Chain | Residue |
B | SER108 |
C | CYS35 |
C | HIS36 |
site_id | BC2 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE SO4 C 302 |
Chain | Residue |
C | PRO63 |
C | TYR64 |
C | GLU65 |
C | ASN70 |
C | HIS118 |
site_id | BC3 |
Number of Residues | 2 |
Details | BINDING SITE FOR RESIDUE SO4 D 301 |
Chain | Residue |
D | CYS35 |
D | HIS36 |
site_id | BC4 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE SO4 D 302 |
Chain | Residue |
A | THR212 |
D | ARG141 |
D | HIS142 |
D | LYS145 |
site_id | BC5 |
Number of Residues | 9 |
Details | BINDING SITE FOR RESIDUE EPE E 301 |
Chain | Residue |
B | LEU209 |
E | TYR44 |
E | LEU45 |
E | GLY46 |
E | TRP82 |
E | GLU83 |
E | GLN135 |
E | TYR139 |
E | HOH414 |
site_id | BC6 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE SO4 E 302 |
Chain | Residue |
E | ARG54 |
E | LYS55 |
E | SER179 |
site_id | BC7 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE SO4 E 303 |
Chain | Residue |
E | SER34 |
E | CYS35 |
E | HIS36 |
site_id | BC8 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE SO4 E 304 |
Chain | Residue |
E | ARG141 |
E | HIS142 |
E | LYS145 |
site_id | BC9 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE SO4 E 305 |
Chain | Residue |
E | GLY235 |
E | LYS237 |
E | SER238 |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 10 |
Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ATG12) => ECO:0000269|PubMed:22682742 |
Chain | Residue | Details |
A | LYS145 | |
B | LYS145 | |
C | LYS145 | |
D | LYS145 | |
E | LYS145 |