3VQI

Crystal structure of Kluyveromyces marxianus Atg5

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000422	biological_process	autophagy of mitochondrion
A	0005737	cellular_component	cytoplasm
A	0005776	cellular_component	autophagosome
A	0006914	biological_process	autophagy
A	0006995	biological_process	cellular response to nitrogen starvation
A	0015031	biological_process	protein transport
A	0016020	cellular_component	membrane
A	0019776	molecular_function	Atg8-family ligase activity
A	0034045	cellular_component	phagophore assembly site membrane
A	0034274	cellular_component	Atg12-Atg5-Atg16 complex
A	0034727	biological_process	piecemeal microautophagy of the nucleus
A	0044233	cellular_component	mitochondria-associated endoplasmic reticulum membrane contact site
A	0061908	cellular_component	phagophore
B	0000422	biological_process	autophagy of mitochondrion
B	0005737	cellular_component	cytoplasm
B	0005776	cellular_component	autophagosome
B	0006914	biological_process	autophagy
B	0006995	biological_process	cellular response to nitrogen starvation
B	0015031	biological_process	protein transport
B	0016020	cellular_component	membrane
B	0019776	molecular_function	Atg8-family ligase activity
B	0034045	cellular_component	phagophore assembly site membrane
B	0034274	cellular_component	Atg12-Atg5-Atg16 complex
B	0034727	biological_process	piecemeal microautophagy of the nucleus
B	0044233	cellular_component	mitochondria-associated endoplasmic reticulum membrane contact site
B	0061908	cellular_component	phagophore
C	0000422	biological_process	autophagy of mitochondrion
C	0005737	cellular_component	cytoplasm
C	0005776	cellular_component	autophagosome
C	0006914	biological_process	autophagy
C	0006995	biological_process	cellular response to nitrogen starvation
C	0015031	biological_process	protein transport
C	0016020	cellular_component	membrane
C	0019776	molecular_function	Atg8-family ligase activity
C	0034045	cellular_component	phagophore assembly site membrane
C	0034274	cellular_component	Atg12-Atg5-Atg16 complex
C	0034727	biological_process	piecemeal microautophagy of the nucleus
C	0044233	cellular_component	mitochondria-associated endoplasmic reticulum membrane contact site
C	0061908	cellular_component	phagophore
D	0000422	biological_process	autophagy of mitochondrion
D	0005737	cellular_component	cytoplasm
D	0005776	cellular_component	autophagosome
D	0006914	biological_process	autophagy
D	0006995	biological_process	cellular response to nitrogen starvation
D	0015031	biological_process	protein transport
D	0016020	cellular_component	membrane
D	0019776	molecular_function	Atg8-family ligase activity
D	0034045	cellular_component	phagophore assembly site membrane
D	0034274	cellular_component	Atg12-Atg5-Atg16 complex
D	0034727	biological_process	piecemeal microautophagy of the nucleus
D	0044233	cellular_component	mitochondria-associated endoplasmic reticulum membrane contact site
D	0061908	cellular_component	phagophore
E	0000422	biological_process	autophagy of mitochondrion
E	0005737	cellular_component	cytoplasm
E	0005776	cellular_component	autophagosome
E	0006914	biological_process	autophagy
E	0006995	biological_process	cellular response to nitrogen starvation
E	0015031	biological_process	protein transport
E	0016020	cellular_component	membrane
E	0019776	molecular_function	Atg8-family ligase activity
E	0034045	cellular_component	phagophore assembly site membrane
E	0034274	cellular_component	Atg12-Atg5-Atg16 complex
E	0034727	biological_process	piecemeal microautophagy of the nucleus
E	0044233	cellular_component	mitochondria-associated endoplasmic reticulum membrane contact site
E	0061908	cellular_component	phagophore

Functional Information from PDB Data

site_id	AC1
Number of Residues	9
Details	BINDING SITE FOR RESIDUE EPE A 301

Chain	Residue
A	LEU45
A	GLY46
A	TRP82
A	GLU83
A	GLN135
A	TYR139
A	HOH402
A	HOH410
D	LEU209

---

site_id	AC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 A 302

Chain	Residue
A	CYS35
A	HIS36

---

site_id	AC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 A 303

Chain	Residue
A	LYS121
E	PRO26
E	ASN27

---

site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 A 304

Chain	Residue
A	LYS121
A	ARG124
A	HOH414
E	HOH411

---

site_id	AC5
Number of Residues	7
Details	BINDING SITE FOR RESIDUE EPE B 301

Chain	Residue
B	LEU45
B	GLY46
B	TRP82
B	GLN135
B	ILE136
B	TYR139
E	LEU209

---

site_id	AC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 B 302

Chain	Residue
A	ARG54
A	LYS55
B	SER179

---

site_id	AC7
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 B 303

Chain	Residue
B	SER34
B	CYS35
B	HIS36

---

site_id	AC8
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 B 304

Chain	Residue
B	ARG141
B	HIS142
B	LYS145

---

site_id	AC9
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 B 305

Chain	Residue
B	LYS121
D	ASP21
D	PRO26
D	ASN27
D	HOH404

---

site_id	BC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 C 301

Chain	Residue
B	SER108
C	CYS35
C	HIS36

---

site_id	BC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 C 302

Chain	Residue
C	PRO63
C	TYR64
C	GLU65
C	ASN70
C	HIS118

---

site_id	BC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 D 301

Chain	Residue
D	CYS35
D	HIS36

---

site_id	BC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 D 302

Chain	Residue
A	THR212
D	ARG141
D	HIS142
D	LYS145

---

site_id	BC5
Number of Residues	9
Details	BINDING SITE FOR RESIDUE EPE E 301

Chain	Residue
B	LEU209
E	TYR44
E	LEU45
E	GLY46
E	TRP82
E	GLU83
E	GLN135
E	TYR139
E	HOH414

---

site_id	BC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 E 302

Chain	Residue
E	ARG54
E	LYS55
E	SER179

---

site_id	BC7
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 E 303

Chain	Residue
E	SER34
E	CYS35
E	HIS36

---

site_id	BC8
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 E 304

Chain	Residue
E	ARG141
E	HIS142
E	LYS145

---

site_id	BC9
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 E 305

Chain	Residue
E	GLY235
E	LYS237
E	SER238

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	10
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ATG12)","evidences":[{"source":"PubMed","id":"22682742","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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