3VQI
Crystal structure of Kluyveromyces marxianus Atg5
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000045 | biological_process | autophagosome assembly |
| A | 0000422 | biological_process | autophagy of mitochondrion |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006501 | biological_process | C-terminal protein lipidation |
| A | 0006914 | biological_process | autophagy |
| A | 0006995 | biological_process | cellular response to nitrogen starvation |
| A | 0015031 | biological_process | protein transport |
| A | 0016020 | cellular_component | membrane |
| A | 0019776 | molecular_function | Atg8-family ligase activity |
| A | 0034045 | cellular_component | phagophore assembly site membrane |
| A | 0034274 | cellular_component | Atg12-Atg5-Atg16 complex |
| A | 0044804 | biological_process | nucleophagy |
| B | 0000045 | biological_process | autophagosome assembly |
| B | 0000422 | biological_process | autophagy of mitochondrion |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006501 | biological_process | C-terminal protein lipidation |
| B | 0006914 | biological_process | autophagy |
| B | 0006995 | biological_process | cellular response to nitrogen starvation |
| B | 0015031 | biological_process | protein transport |
| B | 0016020 | cellular_component | membrane |
| B | 0019776 | molecular_function | Atg8-family ligase activity |
| B | 0034045 | cellular_component | phagophore assembly site membrane |
| B | 0034274 | cellular_component | Atg12-Atg5-Atg16 complex |
| B | 0044804 | biological_process | nucleophagy |
| C | 0000045 | biological_process | autophagosome assembly |
| C | 0000422 | biological_process | autophagy of mitochondrion |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0006501 | biological_process | C-terminal protein lipidation |
| C | 0006914 | biological_process | autophagy |
| C | 0006995 | biological_process | cellular response to nitrogen starvation |
| C | 0015031 | biological_process | protein transport |
| C | 0016020 | cellular_component | membrane |
| C | 0019776 | molecular_function | Atg8-family ligase activity |
| C | 0034045 | cellular_component | phagophore assembly site membrane |
| C | 0034274 | cellular_component | Atg12-Atg5-Atg16 complex |
| C | 0044804 | biological_process | nucleophagy |
| D | 0000045 | biological_process | autophagosome assembly |
| D | 0000422 | biological_process | autophagy of mitochondrion |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0006501 | biological_process | C-terminal protein lipidation |
| D | 0006914 | biological_process | autophagy |
| D | 0006995 | biological_process | cellular response to nitrogen starvation |
| D | 0015031 | biological_process | protein transport |
| D | 0016020 | cellular_component | membrane |
| D | 0019776 | molecular_function | Atg8-family ligase activity |
| D | 0034045 | cellular_component | phagophore assembly site membrane |
| D | 0034274 | cellular_component | Atg12-Atg5-Atg16 complex |
| D | 0044804 | biological_process | nucleophagy |
| E | 0000045 | biological_process | autophagosome assembly |
| E | 0000422 | biological_process | autophagy of mitochondrion |
| E | 0005737 | cellular_component | cytoplasm |
| E | 0006501 | biological_process | C-terminal protein lipidation |
| E | 0006914 | biological_process | autophagy |
| E | 0006995 | biological_process | cellular response to nitrogen starvation |
| E | 0015031 | biological_process | protein transport |
| E | 0016020 | cellular_component | membrane |
| E | 0019776 | molecular_function | Atg8-family ligase activity |
| E | 0034045 | cellular_component | phagophore assembly site membrane |
| E | 0034274 | cellular_component | Atg12-Atg5-Atg16 complex |
| E | 0044804 | biological_process | nucleophagy |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE EPE A 301 |
| Chain | Residue |
| A | LEU45 |
| A | GLY46 |
| A | TRP82 |
| A | GLU83 |
| A | GLN135 |
| A | TYR139 |
| A | HOH402 |
| A | HOH410 |
| D | LEU209 |
| site_id | AC2 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 A 302 |
| Chain | Residue |
| A | CYS35 |
| A | HIS36 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 A 303 |
| Chain | Residue |
| A | LYS121 |
| E | PRO26 |
| E | ASN27 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 304 |
| Chain | Residue |
| A | LYS121 |
| A | ARG124 |
| A | HOH414 |
| E | HOH411 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EPE B 301 |
| Chain | Residue |
| B | LEU45 |
| B | GLY46 |
| B | TRP82 |
| B | GLN135 |
| B | ILE136 |
| B | TYR139 |
| E | LEU209 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 B 302 |
| Chain | Residue |
| A | ARG54 |
| A | LYS55 |
| B | SER179 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 B 303 |
| Chain | Residue |
| B | SER34 |
| B | CYS35 |
| B | HIS36 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 B 304 |
| Chain | Residue |
| B | ARG141 |
| B | HIS142 |
| B | LYS145 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 B 305 |
| Chain | Residue |
| B | LYS121 |
| D | ASP21 |
| D | PRO26 |
| D | ASN27 |
| D | HOH404 |
| site_id | BC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 C 301 |
| Chain | Residue |
| B | SER108 |
| C | CYS35 |
| C | HIS36 |
| site_id | BC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 C 302 |
| Chain | Residue |
| C | PRO63 |
| C | TYR64 |
| C | GLU65 |
| C | ASN70 |
| C | HIS118 |
| site_id | BC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 D 301 |
| Chain | Residue |
| D | CYS35 |
| D | HIS36 |
| site_id | BC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 D 302 |
| Chain | Residue |
| A | THR212 |
| D | ARG141 |
| D | HIS142 |
| D | LYS145 |
| site_id | BC5 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE EPE E 301 |
| Chain | Residue |
| B | LEU209 |
| E | TYR44 |
| E | LEU45 |
| E | GLY46 |
| E | TRP82 |
| E | GLU83 |
| E | GLN135 |
| E | TYR139 |
| E | HOH414 |
| site_id | BC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 E 302 |
| Chain | Residue |
| E | ARG54 |
| E | LYS55 |
| E | SER179 |
| site_id | BC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 E 303 |
| Chain | Residue |
| E | SER34 |
| E | CYS35 |
| E | HIS36 |
| site_id | BC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 E 304 |
| Chain | Residue |
| E | ARG141 |
| E | HIS142 |
| E | LYS145 |
| site_id | BC9 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 E 305 |
| Chain | Residue |
| E | GLY235 |
| E | LYS237 |
| E | SER238 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 10 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ATG12) => ECO:0000269|PubMed:22682742 |
| Chain | Residue | Details |
| A | LYS145 | |
| B | LYS145 | |
| C | LYS145 | |
| D | LYS145 | |
| E | LYS145 |
