3VND
Crystal structure of tryptophan synthase alpha-subunit from the psychrophile Shewanella frigidimarina K14-2
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0000162 | biological_process | tryptophan biosynthetic process |
A | 0004834 | molecular_function | tryptophan synthase activity |
A | 0005829 | cellular_component | cytosol |
A | 0006568 | biological_process | tryptophan metabolic process |
A | 0016829 | molecular_function | lyase activity |
B | 0000162 | biological_process | tryptophan biosynthetic process |
B | 0004834 | molecular_function | tryptophan synthase activity |
B | 0005829 | cellular_component | cytosol |
B | 0006568 | biological_process | tryptophan metabolic process |
B | 0016829 | molecular_function | lyase activity |
C | 0000162 | biological_process | tryptophan biosynthetic process |
C | 0004834 | molecular_function | tryptophan synthase activity |
C | 0005829 | cellular_component | cytosol |
C | 0006568 | biological_process | tryptophan metabolic process |
C | 0016829 | molecular_function | lyase activity |
D | 0000162 | biological_process | tryptophan biosynthetic process |
D | 0004834 | molecular_function | tryptophan synthase activity |
D | 0005829 | cellular_component | cytosol |
D | 0006568 | biological_process | tryptophan metabolic process |
D | 0016829 | molecular_function | lyase activity |
E | 0000162 | biological_process | tryptophan biosynthetic process |
E | 0004834 | molecular_function | tryptophan synthase activity |
E | 0005829 | cellular_component | cytosol |
E | 0006568 | biological_process | tryptophan metabolic process |
E | 0016829 | molecular_function | lyase activity |
F | 0000162 | biological_process | tryptophan biosynthetic process |
F | 0004834 | molecular_function | tryptophan synthase activity |
F | 0005829 | cellular_component | cytosol |
F | 0006568 | biological_process | tryptophan metabolic process |
F | 0016829 | molecular_function | lyase activity |
G | 0000162 | biological_process | tryptophan biosynthetic process |
G | 0004834 | molecular_function | tryptophan synthase activity |
G | 0005829 | cellular_component | cytosol |
G | 0006568 | biological_process | tryptophan metabolic process |
G | 0016829 | molecular_function | lyase activity |
H | 0000162 | biological_process | tryptophan biosynthetic process |
H | 0004834 | molecular_function | tryptophan synthase activity |
H | 0005829 | cellular_component | cytosol |
H | 0006568 | biological_process | tryptophan metabolic process |
H | 0016829 | molecular_function | lyase activity |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 9 |
Details | BINDING SITE FOR RESIDUE SO4 A 301 |
Chain | Residue |
A | GLY212 |
A | PHE213 |
A | GLY214 |
A | GLY235 |
A | SER236 |
A | HOH443 |
A | HOH464 |
A | HOH478 |
B | PRO63 |
site_id | AC2 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE SO4 A 302 |
Chain | Residue |
A | THR78 |
A | SER79 |
A | SER80 |
site_id | AC3 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE SO4 A 303 |
Chain | Residue |
A | HIS93 |
A | PRO94 |
A | ASP95 |
A | MET96 |
A | HOH537 |
site_id | AC4 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE SO4 B 301 |
Chain | Residue |
B | HIS93 |
B | PRO94 |
B | ASP95 |
B | MET96 |
B | HOH419 |
B | HOH487 |
B | HOH548 |
site_id | AC5 |
Number of Residues | 8 |
Details | BINDING SITE FOR RESIDUE SO4 B 302 |
Chain | Residue |
A | PRO63 |
B | GLY212 |
B | PHE213 |
B | GLY214 |
B | GLY235 |
B | SER236 |
B | HOH433 |
B | HOH517 |
site_id | AC6 |
Number of Residues | 9 |
Details | BINDING SITE FOR RESIDUE PE8 B 303 |
Chain | Residue |
A | ALA60 |
A | ASP61 |
A | ALA130 |
A | HOH464 |
A | HOH488 |
B | ASP61 |
B | ALA130 |
B | ILE154 |
B | HOH518 |
site_id | AC7 |
Number of Residues | 9 |
Details | BINDING SITE FOR RESIDUE SO4 C 301 |
Chain | Residue |
C | GLY212 |
C | PHE213 |
C | GLY214 |
C | GLY235 |
C | SER236 |
C | HOH423 |
C | HOH489 |
C | HOH537 |
D | PRO63 |
site_id | AC8 |
Number of Residues | 8 |
Details | BINDING SITE FOR RESIDUE SO4 C 302 |
Chain | Residue |
C | HIS93 |
C | PRO94 |
C | ASP95 |
C | MET96 |
C | HOH402 |
C | HOH455 |
C | HOH463 |
C | HOH551 |
site_id | AC9 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE SO4 D 301 |
Chain | Residue |
D | THR78 |
D | SER79 |
D | SER80 |
D | ASN110 |
D | HOH428 |
D | HOH462 |
site_id | BC1 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE SO4 D 302 |
Chain | Residue |
D | HIS93 |
D | PRO94 |
D | ASP95 |
D | MET96 |
D | HOH416 |
D | HOH420 |
site_id | BC2 |
Number of Residues | 8 |
Details | BINDING SITE FOR RESIDUE SO4 D 303 |
Chain | Residue |
C | PRO63 |
D | GLY212 |
D | PHE213 |
D | GLY214 |
D | GLY235 |
D | SER236 |
D | HOH408 |
D | HOH412 |
site_id | BC3 |
Number of Residues | 16 |
Details | BINDING SITE FOR RESIDUE PE8 D 304 |
Chain | Residue |
C | ALA60 |
C | ILE154 |
C | PHE213 |
D | ALA60 |
D | ASP61 |
D | ALA130 |
D | ILE154 |
D | PRO157 |
D | LEU178 |
D | PHE213 |
D | HOH435 |
D | HOH472 |
D | HOH481 |
D | HOH482 |
D | HOH485 |
D | HOH522 |
site_id | BC4 |
Number of Residues | 8 |
Details | BINDING SITE FOR RESIDUE SO4 E 301 |
Chain | Residue |
E | HOH403 |
E | HOH424 |
F | PRO63 |
E | GLY212 |
E | PHE213 |
E | GLY214 |
E | GLY235 |
E | SER236 |
site_id | BC5 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE SO4 E 302 |
Chain | Residue |
E | HIS93 |
E | ASP95 |
E | MET96 |
E | HOH461 |
E | HOH489 |
site_id | BC6 |
Number of Residues | 10 |
Details | BINDING SITE FOR RESIDUE PE8 E 303 |
Chain | Residue |
E | ALA60 |
E | ASP61 |
E | ALA130 |
E | ILE154 |
E | PRO157 |
E | HOH507 |
E | HOH541 |
F | ASP61 |
F | ILE154 |
F | PHE213 |
site_id | BC7 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE SO4 F 301 |
Chain | Residue |
E | PRO63 |
F | GLY212 |
F | PHE213 |
F | GLY214 |
F | GLY235 |
F | SER236 |
F | HOH417 |
site_id | BC8 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE SO4 F 302 |
Chain | Residue |
F | HIS93 |
F | PRO94 |
F | ASP95 |
F | MET96 |
F | HOH414 |
F | HOH471 |
F | HOH476 |
site_id | BC9 |
Number of Residues | 9 |
Details | BINDING SITE FOR RESIDUE SO4 G 301 |
Chain | Residue |
G | HIS93 |
G | PRO94 |
G | ASP95 |
G | MET96 |
G | HOH438 |
G | HOH462 |
G | HOH469 |
G | HOH478 |
G | HOH514 |
site_id | CC1 |
Number of Residues | 10 |
Details | BINDING SITE FOR RESIDUE SO4 G 302 |
Chain | Residue |
G | GLY212 |
G | PHE213 |
G | GLY214 |
G | GLY235 |
G | SER236 |
G | HOH402 |
G | HOH441 |
G | HOH472 |
G | HOH477 |
H | PRO63 |
site_id | CC2 |
Number of Residues | 10 |
Details | BINDING SITE FOR RESIDUE PE8 G 303 |
Chain | Residue |
G | ASP61 |
G | ALA130 |
G | PRO157 |
G | PHE213 |
G | HOH419 |
G | HOH490 |
G | HOH495 |
G | HOH502 |
H | ALA130 |
H | HOH474 |
site_id | CC3 |
Number of Residues | 10 |
Details | BINDING SITE FOR RESIDUE SO4 H 301 |
Chain | Residue |
G | PRO63 |
H | GLY212 |
H | PHE213 |
H | GLY214 |
H | GLY235 |
H | SER236 |
H | HOH419 |
H | HOH432 |
H | HOH463 |
H | HOH468 |
site_id | CC4 |
Number of Residues | 8 |
Details | BINDING SITE FOR RESIDUE SO4 H 302 |
Chain | Residue |
H | GLN92 |
H | HIS93 |
H | PRO94 |
H | ASP95 |
H | MET96 |
H | HOH444 |
H | HOH472 |
H | HOH513 |
Functional Information from PROSITE/UniProt
site_id | PS00167 |
Number of Residues | 14 |
Details | TRP_SYNTHASE_ALPHA Tryptophan synthase alpha chain signature. LELGfPFSDPLADG |
Chain | Residue | Details |
A | LEU49-GLY62 |