Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000287 | molecular_function | magnesium ion binding |
| A | 0003862 | molecular_function | 3-isopropylmalate dehydrogenase activity |
| A | 0009098 | biological_process | L-leucine biosynthetic process |
| A | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
| A | 0051287 | molecular_function | NAD binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE IPM A 401 |
| Chain | Residue |
| A | ARG97 |
| A | HOH518 |
| A | HOH526 |
| A | HOH557 |
| A | HOH952 |
| A | HOH963 |
| A | ARG107 |
| A | ARG136 |
| A | TYR143 |
| A | LYS193 |
| A | ASN195 |
| A | ASP225 |
| A | ASP249 |
| A | MG402 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG A 402 |
| Chain | Residue |
| A | ASP225 |
| A | ASP249 |
| A | IPM401 |
| A | HOH952 |
| A | HOH963 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL A 403 |
| Chain | Residue |
| A | GLY141 |
| A | ILE142 |
| A | ASN245 |
| A | LEU246 |
| A | HOH964 |
Functional Information from PROSITE/UniProt
| site_id | PS00470 |
| Number of Residues | 20 |
| Details | IDH_IMDH Isocitrate and isopropylmalate dehydrogenases signature. NLFGDIvSDeiAmlt.GSMGL |
| Chain | Residue | Details |
| A | ASN245-LEU264 | |
