3VM4
Cytochrome P450SP alpha (CYP152B1) in complex with (R)-ibuprophen
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004497 | molecular_function | monooxygenase activity |
| A | 0005506 | molecular_function | iron ion binding |
| A | 0016125 | biological_process | sterol metabolic process |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016705 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen |
| A | 0020037 | molecular_function | heme binding |
| A | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 25 |
| Details | BINDING SITE FOR RESIDUE HEM A 501 |
| Chain | Residue |
| A | IZP1 |
| A | PRO242 |
| A | THR243 |
| A | ILE246 |
| A | PHE287 |
| A | PHE288 |
| A | VAL291 |
| A | LEU316 |
| A | GLN350 |
| A | HIS359 |
| A | CYS361 |
| A | TYR58 |
| A | PRO362 |
| A | GLY363 |
| A | VAL367 |
| A | HOH437 |
| A | HOH554 |
| A | HOH612 |
| A | ARG65 |
| A | GLN84 |
| A | HIS91 |
| A | LYS95 |
| A | PHE98 |
| A | MET102 |
| A | ASN238 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE IZP A 1 |
| Chain | Residue |
| A | PHE169 |
| A | ARG241 |
| A | PRO242 |
| A | ALA245 |
| A | PHE287 |
| A | PHE288 |
| A | HEM501 |
| A | HOH554 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE MRD A 416 |
| Chain | Residue |
| A | MET99 |
| A | MET102 |
| A | TYR356 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MRD A 417 |
| Chain | Residue |
| A | HIS255 |
| A | THR259 |
| A | CYS260 |
| A | PHE284 |
| A | TYR285 |
| A | HOH552 |
