3VM4

Cytochrome P450SP alpha (CYP152B1) in complex with (R)-ibuprophen

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004497	molecular_function	monooxygenase activity
A	0005506	molecular_function	iron ion binding
A	0016705	molecular_function	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
A	0020037	molecular_function	heme binding
A	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	25
Details	BINDING SITE FOR RESIDUE HEM A 501

Chain	Residue
A	IZP1
A	PRO242
A	THR243
A	ILE246
A	PHE287
A	PHE288
A	VAL291
A	LEU316
A	GLN350
A	HIS359
A	CYS361
A	TYR58
A	PRO362
A	GLY363
A	VAL367
A	HOH437
A	HOH554
A	HOH612
A	ARG65
A	GLN84
A	HIS91
A	LYS95
A	PHE98
A	MET102
A	ASN238

---

site_id	AC2
Number of Residues	8
Details	BINDING SITE FOR RESIDUE IZP A 1

Chain	Residue
A	PHE169
A	ARG241
A	PRO242
A	ALA245
A	PHE287
A	PHE288
A	HEM501
A	HOH554

---

site_id	AC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MRD A 416

Chain	Residue
A	MET99
A	MET102
A	TYR356

---

site_id	AC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MRD A 417

Chain	Residue
A	HIS255
A	THR259
A	CYS260
A	PHE284
A	TYR285
A	HOH552

---