3VI4
Crystal structure of alpha5beta1 integrin headpiece in complex with RGD peptide
Functional Information from GO Data
Functional Information from PROSITE/UniProt
| site_id | PS00290 |
| Number of Residues | 7 |
| Details | IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YTCEATH |
| Chain | Residue | Details |
| L | TYR197-HIS203 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | BINDING: in MIDAS binding site => ECO:0000269|PubMed:22451694, ECO:0000269|PubMed:33962943, ECO:0007744|PDB:3VI3, ECO:0007744|PDB:3VI4, ECO:0007744|PDB:7NXD |
| Chain | Residue | Details |
| B | SER132 | |
| B | GLU229 | |
| D | SER132 | |
| D | GLU229 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | BINDING: in MIDAS binding site => ECO:0000269|PubMed:22451694, ECO:0007744|PDB:3VI4 |
| Chain | Residue | Details |
| B | SER134 | |
| A | ASP301 | |
| A | ASP360 | |
| A | ASP362 | |
| A | ASP364 | |
| A | TYR366 | |
| A | ASP368 | |
| A | ASP424 | |
| A | ASP426 | |
| A | ASN428 | |
| A | TYR430 | |
| D | SER134 | |
| A | ASP432 | |
| C | GLU239 | |
| C | SER241 | |
| C | ASP243 | |
| C | THR245 | |
| C | ASP247 | |
| C | ASP293 | |
| C | ASN295 | |
| C | ASP297 | |
| C | LEU299 | |
| A | ASP243 | |
| C | ASP301 | |
| C | ASP360 | |
| C | ASP362 | |
| C | ASP364 | |
| C | TYR366 | |
| C | ASP368 | |
| C | ASP424 | |
| C | ASP426 | |
| C | ASN428 | |
| C | TYR430 | |
| A | THR245 | |
| C | ASP432 | |
| A | ASP247 | |
| A | ASP293 | |
| A | ASN295 | |
| A | ASP297 | |
| A | LEU299 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 6 |
| Details | BINDING: in ADMIDAS binding site => ECO:0000269|PubMed:22451694, ECO:0000269|PubMed:33962943, ECO:0007744|PDB:3VI3, ECO:0007744|PDB:7NXD |
| Chain | Residue | Details |
| B | ASP137 | |
| B | ASP138 | |
| B | ALA342 | |
| D | ASP137 | |
| D | ASP138 | |
| D | ALA342 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | BINDING: in LIMBS binding site => ECO:0000269|PubMed:22451694, ECO:0007744|PDB:3VI3, ECO:0007744|PDB:3VI4 |
| Chain | Residue | Details |
| B | GLU169 | |
| D | GLU169 | |
| A | ASN275 | |
| A | ASN568 | |
| C | ASN43 | |
| C | ASN141 | |
| C | ASN275 | |
| C | ASN568 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 6 |
| Details | BINDING: in LIMBS binding site => ECO:0000269|PubMed:22451694, ECO:0000269|PubMed:33962943, ECO:0007744|PDB:3VI3, ECO:0007744|PDB:3VI4, ECO:0007744|PDB:7NXD |
| Chain | Residue | Details |
| B | ASN224 | |
| B | ASP226 | |
| B | PRO228 | |
| D | ASN224 | |
| D | ASP226 | |
| D | PRO228 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 6 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
| Chain | Residue | Details |
| B | ASN30 | |
| B | ASN74 | |
| B | ASN77 | |
| D | ASN30 | |
| D | ASN74 | |
| D | ASN77 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 2 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:19159218 |
| Chain | Residue | Details |
| B | ASN192 | |
| D | ASN192 | |
| C | ASN489 | |
| C | ASN552 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 2 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:22451694, ECO:0000269|PubMed:33962943, ECO:0007744|PDB:3VI3, ECO:0007744|PDB:3VI4, ECO:0007744|PDB:7NWL, ECO:0007744|PDB:7NXD |
| Chain | Residue | Details |
| B | ASN249 | |
| D | ASN249 |
| site_id | SWS_FT_FI9 |
| Number of Residues | 4 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:33962943, ECO:0007744|PDB:7NWL, ECO:0007744|PDB:7NXD |
| Chain | Residue | Details |
| B | ASN343 | |
| B | ASN397 | |
| D | ASN343 | |
| D | ASN397 |
| site_id | SWS_FT_FI10 |
| Number of Residues | 2 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:16335952, ECO:0000269|PubMed:19349973, ECO:0000269|PubMed:22451694, ECO:0000269|PubMed:33962943, ECO:0007744|PDB:3VI3, ECO:0007744|PDB:3VI4, ECO:0007744|PDB:7NWL, ECO:0007744|PDB:7NXD |
| Chain | Residue | Details |
| B | ASN386 | |
| D | ASN386 |
