Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

3VGK

Crystal structure of a ROK family glucokinase from Streptomyces griseus

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0004340	molecular_function	glucokinase activity
A	0005524	molecular_function	ATP binding
A	0005737	cellular_component	cytoplasm
A	0006096	biological_process	glycolytic process
A	0016301	molecular_function	kinase activity
A	0016740	molecular_function	transferase activity
A	0042802	molecular_function	identical protein binding
A	0046872	molecular_function	metal ion binding
A	0051156	biological_process	glucose 6-phosphate metabolic process
B	0000166	molecular_function	nucleotide binding
B	0004340	molecular_function	glucokinase activity
B	0005524	molecular_function	ATP binding
B	0005737	cellular_component	cytoplasm
B	0006096	biological_process	glycolytic process
B	0016301	molecular_function	kinase activity
B	0016740	molecular_function	transferase activity
B	0042802	molecular_function	identical protein binding
B	0046872	molecular_function	metal ion binding
B	0051156	biological_process	glucose 6-phosphate metabolic process
C	0000166	molecular_function	nucleotide binding
C	0004340	molecular_function	glucokinase activity
C	0005524	molecular_function	ATP binding
C	0005737	cellular_component	cytoplasm
C	0006096	biological_process	glycolytic process
C	0016301	molecular_function	kinase activity
C	0016740	molecular_function	transferase activity
C	0042802	molecular_function	identical protein binding
C	0046872	molecular_function	metal ion binding
C	0051156	biological_process	glucose 6-phosphate metabolic process
D	0000166	molecular_function	nucleotide binding
D	0004340	molecular_function	glucokinase activity
D	0005524	molecular_function	ATP binding
D	0005737	cellular_component	cytoplasm
D	0006096	biological_process	glycolytic process
D	0016301	molecular_function	kinase activity
D	0016740	molecular_function	transferase activity
D	0042802	molecular_function	identical protein binding
D	0046872	molecular_function	metal ion binding
D	0051156	biological_process	glucose 6-phosphate metabolic process
E	0000166	molecular_function	nucleotide binding
E	0004340	molecular_function	glucokinase activity
E	0005524	molecular_function	ATP binding
E	0005737	cellular_component	cytoplasm
E	0006096	biological_process	glycolytic process
E	0016301	molecular_function	kinase activity
E	0016740	molecular_function	transferase activity
E	0042802	molecular_function	identical protein binding
E	0046872	molecular_function	metal ion binding
E	0051156	biological_process	glucose 6-phosphate metabolic process
F	0000166	molecular_function	nucleotide binding
F	0004340	molecular_function	glucokinase activity
F	0005524	molecular_function	ATP binding
F	0005737	cellular_component	cytoplasm
F	0006096	biological_process	glycolytic process
F	0016301	molecular_function	kinase activity
F	0016740	molecular_function	transferase activity
F	0042802	molecular_function	identical protein binding
F	0046872	molecular_function	metal ion binding
F	0051156	biological_process	glucose 6-phosphate metabolic process
G	0000166	molecular_function	nucleotide binding
G	0004340	molecular_function	glucokinase activity
G	0005524	molecular_function	ATP binding
G	0005737	cellular_component	cytoplasm
G	0006096	biological_process	glycolytic process
G	0016301	molecular_function	kinase activity
G	0016740	molecular_function	transferase activity
G	0042802	molecular_function	identical protein binding
G	0046872	molecular_function	metal ion binding
G	0051156	biological_process	glucose 6-phosphate metabolic process
H	0000166	molecular_function	nucleotide binding
H	0004340	molecular_function	glucokinase activity
H	0005524	molecular_function	ATP binding
H	0005737	cellular_component	cytoplasm
H	0006096	biological_process	glycolytic process
H	0016301	molecular_function	kinase activity
H	0016740	molecular_function	transferase activity
H	0042802	molecular_function	identical protein binding
H	0046872	molecular_function	metal ion binding
H	0051156	biological_process	glucose 6-phosphate metabolic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 322

Chain	Residue
A	HIS157
A	CYS167
A	CYS169
A	CYS174

site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN F 322

Chain	Residue
F	HIS157
F	CYS167
F	CYS169
F	CYS174

site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN B 322

Chain	Residue
B	CYS167
B	CYS169
B	CYS174
B	HIS157

site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN E 322

Chain	Residue
E	HIS157
E	CYS167
E	CYS169
E	CYS174

site_id	AC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN H 322

Chain	Residue
H	HIS157
H	CYS167
H	CYS169
H	CYS174

site_id	AC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN C 322

Chain	Residue
C	HIS157
C	CYS167
C	CYS169
C	CYS174

site_id	AC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN G 322

Chain	Residue
G	HIS157
G	CYS167
G	CYS169
G	CYS174

site_id	AC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN D 322

Chain	Residue
D	HIS157
D	CYS167
D	CYS169
D	CYS174

site_id	AC9
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 B 323

Chain	Residue
B	ALA65
B	ASN104
B	ASP105
B	GLU154

site_id	BC1
Number of Residues	1
Details	BINDING SITE FOR RESIDUE SO4 E 323

Chain	Residue
E	GLU154

Functional Information from PROSITE/UniProt

site_id	PS01125
Number of Residues	28
Details	ROK ROK family signature. LgtGLGgGIiigNklrrGrfgvaAEfGH

Chain	Residue	Details
A	LEU130-HIS157

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)