Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| B | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| B | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 25 |
| Details | BINDING SITE FOR RESIDUE 031 A 201 |
| Chain | Residue |
| A | LEU23 |
| A | PRO81 |
| A | VAL82 |
| A | ILE84 |
| A | HOH1001 |
| A | HOH1069 |
| B | ASP25 |
| B | GLY27 |
| B | ALA28 |
| B | ASP30 |
| B | VAL32 |
| A | ASP25 |
| B | GLY48 |
| B | GLY49 |
| B | PRO81 |
| B | VAL82 |
| B | ILE84 |
| B | GOL503 |
| A | GLY27 |
| A | ALA28 |
| A | ASP29 |
| A | ASP30 |
| A | GLY48 |
| A | GLY49 |
| A | ILE50 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NA A 202 |
| Chain | Residue |
| A | HOH1016 |
| A | HOH1041 |
| A | HOH1063 |
| A | HOH1071 |
| A | HOH1076 |
| A | HOH1105 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL A 203 |
| Chain | Residue |
| A | TRP6 |
| A | LYS55 |
| A | GOL206 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL A 204 |
| Chain | Residue |
| A | THR74 |
| A | ASN88 |
| A | HOH1015 |
| site_id | AC5 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL A 205 |
| Chain | Residue |
| A | GLN61 |
| A | GLN92 |
| A | HOH1006 |
| A | HOH1007 |
| A | HOH1068 |
| B | LYS45 |
| B | MET46 |
| B | PHE53 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL A 206 |
| Chain | Residue |
| A | THR4 |
| A | TRP6 |
| A | PRO44 |
| A | LYS55 |
| A | CL203 |
| A | HOH1042 |
| A | HOH1046 |
| site_id | AC7 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE GOL A 207 |
| Chain | Residue |
| A | THR12 |
| A | GLU65 |
| A | ILE66 |
| A | ALA67 |
| A | GLY68 |
| A | HOH1037 |
| A | HOH1084 |
| B | GLN18 |
| B | MET36 |
| B | SER37 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL A 208 |
| Chain | Residue |
| A | GLY40 |
| A | HOH1025 |
| A | HOH1071 |
| B | LYS70 |
| B | ALA71 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NA B 501 |
| Chain | Residue |
| B | ASP60 |
| B | HOH630 |
| B | HOH631 |
| B | HOH632 |
| B | HOH634 |
| B | HOH674 |
| site_id | BC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL B 502 |
| Chain | Residue |
| A | ARG41 |
| B | THR74 |
| B | ASN88 |
| site_id | BC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL B 503 |
| Chain | Residue |
| A | 031201 |
| A | HOH1039 |
| B | ARG8 |
| B | VAL82 |
Functional Information from PROSITE/UniProt
| site_id | PS00141 |
| Number of Residues | 12 |
| Details | ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. ALLDTGADDTVI |
| Chain | Residue | Details |
| A | ALA22-ILE33 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | ASP25 | |
| B | ASP25 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | SITE: Cleavage; by viral protease => ECO:0000250 |
| Chain | Residue | Details |
| A | PHE99 | |
| B | PHE99 | |
