3VEP

Crystal structure of SigD4 in complex with its negative regulator RsdA

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003677	molecular_function	DNA binding
A	0003700	molecular_function	DNA-binding transcription factor activity
A	0006352	biological_process	DNA-templated transcription initiation
A	0006355	biological_process	regulation of DNA-templated transcription
A	0016987	molecular_function	sigma factor activity
D	0003677	molecular_function	DNA binding
D	0003700	molecular_function	DNA-binding transcription factor activity
D	0006352	biological_process	DNA-templated transcription initiation
D	0006355	biological_process	regulation of DNA-templated transcription
D	0016987	molecular_function	sigma factor activity
E	0003677	molecular_function	DNA binding
E	0003700	molecular_function	DNA-binding transcription factor activity
E	0006352	biological_process	DNA-templated transcription initiation
E	0006355	biological_process	regulation of DNA-templated transcription
E	0016987	molecular_function	sigma factor activity
H	0003677	molecular_function	DNA binding
H	0003700	molecular_function	DNA-binding transcription factor activity
H	0006352	biological_process	DNA-templated transcription initiation
H	0006355	biological_process	regulation of DNA-templated transcription
H	0016987	molecular_function	sigma factor activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE SO4 X 101

Chain	Residue
A	PRO159
A	ARG196
A	ARG200
X	PRO12
X	PRO13
X	LEU14

---

site_id	AC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 D 301

Chain	Residue
D	ARG191
X	LEU14
X	LEU17

---

site_id	AC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 D 302

Chain	Residue
A	GLY188
A	ARG191
D	SER185
D	THR186
D	ALA189

---

site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 C 101

Chain	Residue
C	PRO13
C	LEU14
D	GLN162
D	ARG196

---

site_id	AC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 A 301

Chain	Residue
A	GLN162
A	ALA193
A	ARG196
A	HOH402
A	HOH403

---

site_id	AC6
Number of Residues	6
Details	BINDING SITE FOR RESIDUE SO4 A 302

Chain	Residue
A	SER185
A	THR186
A	ALA189
A	HOH409
D	THR186
D	GLY188

---

site_id	AC7
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 E 301

Chain	Residue
E	THR186
E	GLY188
H	SER185
H	THR186
H	ALA189

---

site_id	AC8
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 E 302

Chain	Residue
E	SER185
E	THR186
E	ALA189
H	GLY188
H	ARG191

---

site_id	AC9
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 E 303

Chain	Residue
E	GLN162
E	ARG196
J	PRO13
J	LEU14

---

site_id	BC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 H 301

Chain	Residue
G	LEU14
H	LYS161
H	GLN162
H	ALA193
H	ARG196

---

site_id	BC2
Number of Residues	1
Details	BINDING SITE FOR RESIDUE SO4 H 302

Chain	Residue
H	HIS195

---

site_id	BC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 H 303

Chain	Residue
E	ARG191
G	LEU14
G	LEU17
H	LYS161

---

site_id	BC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 H 304

Chain	Residue
G	PRO12
G	PRO13
G	LEU14
H	ARG196
H	ARG200

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	104
Details	Region: {"description":"Interaction with sigma factor"}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	76
Details	DNA binding: {"description":"H-T-H motif","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---