3VEP
Crystal structure of SigD4 in complex with its negative regulator RsdA
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003677 | molecular_function | DNA binding |
| A | 0003700 | molecular_function | DNA-binding transcription factor activity |
| A | 0006352 | biological_process | DNA-templated transcription initiation |
| A | 0006355 | biological_process | regulation of DNA-templated transcription |
| A | 0016987 | molecular_function | sigma factor activity |
| D | 0003677 | molecular_function | DNA binding |
| D | 0003700 | molecular_function | DNA-binding transcription factor activity |
| D | 0006352 | biological_process | DNA-templated transcription initiation |
| D | 0006355 | biological_process | regulation of DNA-templated transcription |
| D | 0016987 | molecular_function | sigma factor activity |
| E | 0003677 | molecular_function | DNA binding |
| E | 0003700 | molecular_function | DNA-binding transcription factor activity |
| E | 0006352 | biological_process | DNA-templated transcription initiation |
| E | 0006355 | biological_process | regulation of DNA-templated transcription |
| E | 0016987 | molecular_function | sigma factor activity |
| H | 0003677 | molecular_function | DNA binding |
| H | 0003700 | molecular_function | DNA-binding transcription factor activity |
| H | 0006352 | biological_process | DNA-templated transcription initiation |
| H | 0006355 | biological_process | regulation of DNA-templated transcription |
| H | 0016987 | molecular_function | sigma factor activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 X 101 |
| Chain | Residue |
| A | PRO159 |
| A | ARG196 |
| A | ARG200 |
| X | PRO12 |
| X | PRO13 |
| X | LEU14 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 D 301 |
| Chain | Residue |
| D | ARG191 |
| X | LEU14 |
| X | LEU17 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 D 302 |
| Chain | Residue |
| A | GLY188 |
| A | ARG191 |
| D | SER185 |
| D | THR186 |
| D | ALA189 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 C 101 |
| Chain | Residue |
| C | PRO13 |
| C | LEU14 |
| D | GLN162 |
| D | ARG196 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 301 |
| Chain | Residue |
| A | GLN162 |
| A | ALA193 |
| A | ARG196 |
| A | HOH402 |
| A | HOH403 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 A 302 |
| Chain | Residue |
| A | SER185 |
| A | THR186 |
| A | ALA189 |
| A | HOH409 |
| D | THR186 |
| D | GLY188 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 E 301 |
| Chain | Residue |
| E | THR186 |
| E | GLY188 |
| H | SER185 |
| H | THR186 |
| H | ALA189 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 E 302 |
| Chain | Residue |
| E | SER185 |
| E | THR186 |
| E | ALA189 |
| H | GLY188 |
| H | ARG191 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 E 303 |
| Chain | Residue |
| E | GLN162 |
| E | ARG196 |
| J | PRO13 |
| J | LEU14 |
| site_id | BC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 H 301 |
| Chain | Residue |
| G | LEU14 |
| H | LYS161 |
| H | GLN162 |
| H | ALA193 |
| H | ARG196 |
| site_id | BC2 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE SO4 H 302 |
| Chain | Residue |
| H | HIS195 |
| site_id | BC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 H 303 |
| Chain | Residue |
| E | ARG191 |
| G | LEU14 |
| G | LEU17 |
| H | LYS161 |
| site_id | BC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 H 304 |
| Chain | Residue |
| G | PRO12 |
| G | PRO13 |
| G | LEU14 |
| H | ARG196 |
| H | ARG200 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 76 |
| Details | DNA_BIND: H-T-H motif => ECO:0000250 |
| Chain | Residue | Details |
| D | ALA176-HIS195 | |
| A | ALA176-HIS195 | |
| E | ALA176-HIS195 | |
| H | ALA176-HIS195 |
