3VC1
Crystal structure of geranyl diphosphate C-methyltransferase from Streptomyces coelicolor A3(2) in complex with Mg2+, geranyl-S-thiolodiphosphate, and S-adenosyl-L-homocysteine
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000287 | molecular_function | magnesium ion binding |
| A | 0008168 | molecular_function | methyltransferase activity |
| A | 0008169 | molecular_function | C-methyltransferase activity |
| A | 0008757 | molecular_function | S-adenosylmethionine-dependent methyltransferase activity |
| A | 0032259 | biological_process | methylation |
| A | 0042214 | biological_process | terpene metabolic process |
| A | 1904047 | molecular_function | S-adenosyl-L-methionine binding |
| B | 0000287 | molecular_function | magnesium ion binding |
| B | 0008168 | molecular_function | methyltransferase activity |
| B | 0008169 | molecular_function | C-methyltransferase activity |
| B | 0008757 | molecular_function | S-adenosylmethionine-dependent methyltransferase activity |
| B | 0032259 | biological_process | methylation |
| B | 0042214 | biological_process | terpene metabolic process |
| B | 1904047 | molecular_function | S-adenosyl-L-methionine binding |
| C | 0000287 | molecular_function | magnesium ion binding |
| C | 0008168 | molecular_function | methyltransferase activity |
| C | 0008169 | molecular_function | C-methyltransferase activity |
| C | 0008757 | molecular_function | S-adenosylmethionine-dependent methyltransferase activity |
| C | 0032259 | biological_process | methylation |
| C | 0042214 | biological_process | terpene metabolic process |
| C | 1904047 | molecular_function | S-adenosyl-L-methionine binding |
| D | 0000287 | molecular_function | magnesium ion binding |
| D | 0008168 | molecular_function | methyltransferase activity |
| D | 0008169 | molecular_function | C-methyltransferase activity |
| D | 0008757 | molecular_function | S-adenosylmethionine-dependent methyltransferase activity |
| D | 0032259 | biological_process | methylation |
| D | 0042214 | biological_process | terpene metabolic process |
| D | 1904047 | molecular_function | S-adenosyl-L-methionine binding |
| E | 0000287 | molecular_function | magnesium ion binding |
| E | 0008168 | molecular_function | methyltransferase activity |
| E | 0008169 | molecular_function | C-methyltransferase activity |
| E | 0008757 | molecular_function | S-adenosylmethionine-dependent methyltransferase activity |
| E | 0032259 | biological_process | methylation |
| E | 0042214 | biological_process | terpene metabolic process |
| E | 1904047 | molecular_function | S-adenosyl-L-methionine binding |
| F | 0000287 | molecular_function | magnesium ion binding |
| F | 0008168 | molecular_function | methyltransferase activity |
| F | 0008169 | molecular_function | C-methyltransferase activity |
| F | 0008757 | molecular_function | S-adenosylmethionine-dependent methyltransferase activity |
| F | 0032259 | biological_process | methylation |
| F | 0042214 | biological_process | terpene metabolic process |
| F | 1904047 | molecular_function | S-adenosyl-L-methionine binding |
| G | 0000287 | molecular_function | magnesium ion binding |
| G | 0008168 | molecular_function | methyltransferase activity |
| G | 0008169 | molecular_function | C-methyltransferase activity |
| G | 0008757 | molecular_function | S-adenosylmethionine-dependent methyltransferase activity |
| G | 0032259 | biological_process | methylation |
| G | 0042214 | biological_process | terpene metabolic process |
| G | 1904047 | molecular_function | S-adenosyl-L-methionine binding |
| H | 0000287 | molecular_function | magnesium ion binding |
| H | 0008168 | molecular_function | methyltransferase activity |
| H | 0008169 | molecular_function | C-methyltransferase activity |
| H | 0008757 | molecular_function | S-adenosylmethionine-dependent methyltransferase activity |
| H | 0032259 | biological_process | methylation |
| H | 0042214 | biological_process | terpene metabolic process |
| H | 1904047 | molecular_function | S-adenosyl-L-methionine binding |
| I | 0000287 | molecular_function | magnesium ion binding |
| I | 0008168 | molecular_function | methyltransferase activity |
| I | 0008169 | molecular_function | C-methyltransferase activity |
| I | 0008757 | molecular_function | S-adenosylmethionine-dependent methyltransferase activity |
| I | 0032259 | biological_process | methylation |
| I | 0042214 | biological_process | terpene metabolic process |
| I | 1904047 | molecular_function | S-adenosyl-L-methionine binding |
| J | 0000287 | molecular_function | magnesium ion binding |
| J | 0008168 | molecular_function | methyltransferase activity |
| J | 0008169 | molecular_function | C-methyltransferase activity |
| J | 0008757 | molecular_function | S-adenosylmethionine-dependent methyltransferase activity |
| J | 0032259 | biological_process | methylation |
| J | 0042214 | biological_process | terpene metabolic process |
| J | 1904047 | molecular_function | S-adenosyl-L-methionine binding |
| K | 0000287 | molecular_function | magnesium ion binding |
| K | 0008168 | molecular_function | methyltransferase activity |
| K | 0008169 | molecular_function | C-methyltransferase activity |
| K | 0008757 | molecular_function | S-adenosylmethionine-dependent methyltransferase activity |
| K | 0032259 | biological_process | methylation |
| K | 0042214 | biological_process | terpene metabolic process |
| K | 1904047 | molecular_function | S-adenosyl-L-methionine binding |
| L | 0000287 | molecular_function | magnesium ion binding |
| L | 0008168 | molecular_function | methyltransferase activity |
| L | 0008169 | molecular_function | C-methyltransferase activity |
| L | 0008757 | molecular_function | S-adenosylmethionine-dependent methyltransferase activity |
| L | 0032259 | biological_process | methylation |
| L | 0042214 | biological_process | terpene metabolic process |
| L | 1904047 | molecular_function | S-adenosyl-L-methionine binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG A 301 |
| Chain | Residue |
| A | ASN37 |
| A | GST303 |
| A | HOH401 |
| A | HOH402 |
| A | HOH403 |
| site_id | AC2 |
| Number of Residues | 23 |
| Details | BINDING SITE FOR RESIDUE SAH A 302 |
| Chain | Residue |
| A | HIS50 |
| A | GLY105 |
| A | GLY107 |
| A | THR127 |
| A | LEU128 |
| A | GLN132 |
| A | CYS154 |
| A | ASN155 |
| A | MET156 |
| A | ASN172 |
| A | GLU173 |
| A | SER174 |
| A | TYR177 |
| A | VAL178 |
| A | HOH457 |
| A | HOH458 |
| A | HOH463 |
| A | HOH468 |
| A | HOH507 |
| A | GLN22 |
| A | TRP29 |
| A | HIS48 |
| A | HIS49 |
| site_id | AC3 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE GST A 303 |
| Chain | Residue |
| A | TRP29 |
| A | ARG34 |
| A | VAL36 |
| A | ASN37 |
| A | HIS49 |
| A | HIS50 |
| A | TYR51 |
| A | TYR177 |
| A | GLY202 |
| A | PHE222 |
| A | ARG260 |
| A | PHE282 |
| A | MG301 |
| A | HOH401 |
| A | HOH402 |
| A | HOH403 |
| A | HOH461 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL A 304 |
| Chain | Residue |
| A | THR19 |
| A | ASN155 |
| A | LEU157 |
| A | HOH421 |
| A | HOH526 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL A 305 |
| Chain | Residue |
| A | ASP179 |
| A | LEU180 |
| A | HIS181 |
| A | HIS227 |
| A | GLU231 |
| A | HOH519 |
| site_id | AC6 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE GOL A 306 |
| Chain | Residue |
| A | PRO206 |
| A | GLY209 |
| A | GLN210 |
| A | ARG230 |
| A | HOH498 |
| D | VAL292 |
| E | ASP179 |
| E | GOL306 |
| E | HOH420 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG B 301 |
| Chain | Residue |
| B | ASN37 |
| B | GST303 |
| B | HOH401 |
| B | HOH402 |
| B | HOH403 |
| site_id | AC8 |
| Number of Residues | 21 |
| Details | BINDING SITE FOR RESIDUE SAH B 302 |
| Chain | Residue |
| B | GLN22 |
| B | TRP29 |
| B | HIS49 |
| B | HIS50 |
| B | GLY105 |
| B | GLY107 |
| B | THR127 |
| B | LEU128 |
| B | GLN132 |
| B | CYS154 |
| B | ASN155 |
| B | MET156 |
| B | ASN172 |
| B | GLU173 |
| B | SER174 |
| B | TYR177 |
| B | HOH449 |
| B | HOH451 |
| B | HOH452 |
| B | HOH455 |
| B | HOH456 |
| site_id | AC9 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE GST B 303 |
| Chain | Residue |
| B | PHE222 |
| B | ARG260 |
| B | PHE282 |
| B | MG301 |
| B | HOH401 |
| B | HOH403 |
| B | HOH437 |
| B | TRP29 |
| B | ARG34 |
| B | VAL36 |
| B | ASN37 |
| B | HIS49 |
| B | HIS50 |
| B | TYR51 |
| B | TYR177 |
| site_id | BC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL B 304 |
| Chain | Residue |
| B | PRO206 |
| B | GLY209 |
| B | GLN210 |
| B | ARG230 |
| B | HOH433 |
| B | HOH503 |
| F | ASP179 |
| site_id | BC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG C 301 |
| Chain | Residue |
| C | ASN37 |
| C | GST303 |
| C | HOH401 |
| C | HOH402 |
| C | HOH403 |
| site_id | BC3 |
| Number of Residues | 22 |
| Details | BINDING SITE FOR RESIDUE SAH C 302 |
| Chain | Residue |
| C | GLN22 |
| C | TRP29 |
| C | HIS49 |
| C | HIS50 |
| C | GLY105 |
| C | GLY107 |
| C | THR127 |
| C | LEU128 |
| C | GLN132 |
| C | CYS154 |
| C | ASN155 |
| C | MET156 |
| C | ASN172 |
| C | GLU173 |
| C | SER174 |
| C | TYR177 |
| C | VAL178 |
| C | HOH441 |
| C | HOH443 |
| C | HOH447 |
| C | HOH448 |
| C | HOH468 |
| site_id | BC4 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE GST C 303 |
| Chain | Residue |
| C | TRP29 |
| C | ARG34 |
| C | VAL36 |
| C | ASN37 |
| C | HIS49 |
| C | HIS50 |
| C | TYR51 |
| C | TYR177 |
| C | PHE222 |
| C | ARG260 |
| C | MG301 |
| C | HOH401 |
| C | HOH403 |
| C | HOH484 |
| site_id | BC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL C 304 |
| Chain | Residue |
| C | GLU86 |
| C | MET114 |
| C | ARG117 |
| C | ARG118 |
| site_id | BC6 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE GOL C 305 |
| Chain | Residue |
| C | TYR28 |
| C | ASN31 |
| C | GLU32 |
| C | ARG34 |
| C | HOH455 |
| C | HOH486 |
| C | HOH531 |
| K | ILE145 |
| K | HOH505 |
| site_id | BC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG D 301 |
| Chain | Residue |
| D | ASN37 |
| D | GST303 |
| D | HOH401 |
| D | HOH402 |
| D | HOH403 |
| site_id | BC8 |
| Number of Residues | 20 |
| Details | BINDING SITE FOR RESIDUE SAH D 302 |
| Chain | Residue |
| D | GLN22 |
| D | TRP29 |
| D | HIS49 |
| D | HIS50 |
| D | GLY105 |
| D | GLY107 |
| D | THR127 |
| D | LEU128 |
| D | GLN132 |
| D | CYS154 |
| D | ASN155 |
| D | MET156 |
| D | ASN172 |
| D | SER174 |
| D | TYR177 |
| D | HOH451 |
| D | HOH452 |
| D | HOH453 |
| D | HOH462 |
| D | HOH478 |
| site_id | BC9 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE GST D 303 |
| Chain | Residue |
| D | TRP29 |
| D | ARG34 |
| D | VAL36 |
| D | ASN37 |
| D | HIS49 |
| D | HIS50 |
| D | TYR51 |
| D | TYR177 |
| D | PHE222 |
| D | ARG260 |
| D | PHE282 |
| D | MG301 |
| D | HOH401 |
| D | HOH402 |
| D | HOH403 |
| D | HOH470 |
| site_id | CC1 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL D 304 |
| Chain | Residue |
| C | ASP179 |
| C | HOH521 |
| D | PRO206 |
| D | GLY209 |
| D | GLN210 |
| D | ARG230 |
| D | HOH419 |
| D | HOH524 |
| site_id | CC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG E 301 |
| Chain | Residue |
| E | ASN37 |
| E | GST303 |
| E | HOH401 |
| E | HOH402 |
| E | HOH403 |
| site_id | CC3 |
| Number of Residues | 21 |
| Details | BINDING SITE FOR RESIDUE SAH E 302 |
| Chain | Residue |
| E | GLN22 |
| E | TRP29 |
| E | HIS49 |
| E | HIS50 |
| E | GLY105 |
| E | GLY107 |
| E | THR127 |
| E | LEU128 |
| E | GLN132 |
| E | CYS154 |
| E | ASN155 |
| E | MET156 |
| E | ASN172 |
| E | SER174 |
| E | TYR177 |
| E | VAL178 |
| E | HOH443 |
| E | HOH444 |
| E | HOH445 |
| E | HOH447 |
| E | HOH490 |
| site_id | CC4 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE GST E 303 |
| Chain | Residue |
| E | TRP29 |
| E | VAL36 |
| E | ASN37 |
| E | HIS49 |
| E | HIS50 |
| E | TYR51 |
| E | TYR177 |
| E | GLY202 |
| E | PHE222 |
| E | ARG260 |
| E | PHE282 |
| E | MG301 |
| E | HOH401 |
| E | HOH403 |
| E | HOH450 |
| E | HOH511 |
| E | HOH513 |
| site_id | CC5 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE SO4 E 304 |
| Chain | Residue |
| E | TYR28 |
| E | ARG34 |
| E | HIS221 |
| E | HOH450 |
| E | HOH492 |
| E | HOH511 |
| H | ARG138 |
| H | HOH453 |
| H | HOH474 |
| site_id | CC6 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL E 305 |
| Chain | Residue |
| E | PHE135 |
| E | ARG138 |
| E | ARG139 |
| E | GLU142 |
| E | HOH515 |
| E | HOH530 |
| H | ARG39 |
| H | ILE74 |
| site_id | CC7 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL E 306 |
| Chain | Residue |
| A | GLY209 |
| A | GOL306 |
| E | THR19 |
| E | ASN155 |
| E | LEU157 |
| E | ASP182 |
| E | HOH420 |
| E | HOH433 |
| site_id | CC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG F 301 |
| Chain | Residue |
| F | ASN37 |
| F | GST303 |
| F | HOH401 |
| F | HOH402 |
| F | HOH403 |
| site_id | CC9 |
| Number of Residues | 23 |
| Details | BINDING SITE FOR RESIDUE SAH F 302 |
| Chain | Residue |
| F | GLN22 |
| F | TRP29 |
| F | HIS49 |
| F | HIS50 |
| F | GLY105 |
| F | CYS106 |
| F | GLY107 |
| F | THR127 |
| F | LEU128 |
| F | GLN132 |
| F | CYS154 |
| F | ASN155 |
| F | MET156 |
| F | ASN172 |
| F | GLU173 |
| F | SER174 |
| F | TYR177 |
| F | VAL178 |
| F | HOH425 |
| F | HOH431 |
| F | HOH434 |
| F | HOH440 |
| F | HOH447 |
| site_id | DC1 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE GST F 303 |
| Chain | Residue |
| F | TRP29 |
| F | ARG34 |
| F | ASN37 |
| F | HIS49 |
| F | HIS50 |
| F | TYR51 |
| F | MET176 |
| F | TYR177 |
| F | GLY202 |
| F | PHE222 |
| F | ARG260 |
| F | PHE282 |
| F | MG301 |
| F | HOH401 |
| F | HOH403 |
| F | HOH484 |
| site_id | DC2 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL F 304 |
| Chain | Residue |
| B | HOH443 |
| C | VAL292 |
| F | TRP204 |
| F | PRO206 |
| F | GLY209 |
| F | GLN210 |
| F | ARG230 |
| F | HOH460 |
| site_id | DC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG G 301 |
| Chain | Residue |
| G | ASN37 |
| G | GST303 |
| G | HOH401 |
| G | HOH402 |
| G | HOH403 |
| site_id | DC4 |
| Number of Residues | 22 |
| Details | BINDING SITE FOR RESIDUE SAH G 302 |
| Chain | Residue |
| G | GLN22 |
| G | TRP29 |
| G | HIS48 |
| G | HIS49 |
| G | HIS50 |
| G | GLY105 |
| G | GLY107 |
| G | THR127 |
| G | LEU128 |
| G | GLN132 |
| G | CYS154 |
| G | ASN155 |
| G | MET156 |
| G | ASN172 |
| G | GLU173 |
| G | SER174 |
| G | TYR177 |
| G | HOH451 |
| G | HOH452 |
| G | HOH453 |
| G | HOH455 |
| G | HOH460 |
| site_id | DC5 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE GST G 303 |
| Chain | Residue |
| G | TRP29 |
| G | ARG34 |
| G | VAL36 |
| G | ASN37 |
| G | HIS49 |
| G | HIS50 |
| G | TYR51 |
| G | GLU173 |
| G | TYR177 |
| G | PHE222 |
| G | ARG260 |
| G | PHE282 |
| G | MG301 |
| G | HOH401 |
| G | HOH403 |
| G | HOH463 |
| G | HOH507 |
| site_id | DC6 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE GOL G 304 |
| Chain | Residue |
| G | GLY209 |
| G | GLN210 |
| G | ARG230 |
| G | HOH461 |
| G | HOH522 |
| J | ARG240 |
| J | VAL292 |
| L | ASP179 |
| L | ASP182 |
| L | HOH497 |
| site_id | DC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG H 301 |
| Chain | Residue |
| H | ASN37 |
| H | GST303 |
| H | HOH401 |
| H | HOH402 |
| H | HOH403 |
| site_id | DC8 |
| Number of Residues | 23 |
| Details | BINDING SITE FOR RESIDUE SAH H 302 |
| Chain | Residue |
| H | GLN22 |
| H | TRP29 |
| H | HIS48 |
| H | HIS49 |
| H | HIS50 |
| H | GLY105 |
| H | GLY107 |
| H | THR127 |
| H | LEU128 |
| H | GLN132 |
| H | CYS154 |
| H | ASN155 |
| H | MET156 |
| H | ASN172 |
| H | GLU173 |
| H | SER174 |
| H | TYR177 |
| H | VAL178 |
| H | HOH465 |
| H | HOH466 |
| H | HOH468 |
| H | HOH476 |
| H | HOH481 |
| site_id | DC9 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE GST H 303 |
| Chain | Residue |
| H | TRP29 |
| H | ARG34 |
| H | VAL36 |
| H | ASN37 |
| H | HIS49 |
| H | HIS50 |
| H | TYR51 |
| H | TYR177 |
| H | PHE222 |
| H | ARG260 |
| H | PHE282 |
| H | MG301 |
| H | HOH401 |
| H | HOH402 |
| H | HOH403 |
| H | HOH471 |
| site_id | EC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL H 304 |
| Chain | Residue |
| H | TRP204 |
| H | PRO206 |
| H | GLY209 |
| H | GLN210 |
| H | ARG230 |
| H | HOH408 |
| J | HOH431 |
| site_id | EC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG I 301 |
| Chain | Residue |
| I | ASN37 |
| I | GST303 |
| I | GOL304 |
| I | HOH401 |
| I | HOH402 |
| site_id | EC3 |
| Number of Residues | 23 |
| Details | BINDING SITE FOR RESIDUE SAH I 302 |
| Chain | Residue |
| I | GLN22 |
| I | TRP29 |
| I | HIS48 |
| I | HIS49 |
| I | HIS50 |
| I | GLY105 |
| I | GLY107 |
| I | THR127 |
| I | LEU128 |
| I | GLN132 |
| I | CYS154 |
| I | ASN155 |
| I | MET156 |
| I | ASN172 |
| I | GLU173 |
| I | SER174 |
| I | TYR177 |
| I | VAL178 |
| I | HOH442 |
| I | HOH445 |
| I | HOH447 |
| I | HOH449 |
| I | HOH490 |
| site_id | EC4 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE GST I 303 |
| Chain | Residue |
| I | TRP29 |
| I | ARG34 |
| I | ASN37 |
| I | HIS49 |
| I | TYR51 |
| I | GLU173 |
| I | TYR177 |
| I | PHE222 |
| I | ARG260 |
| I | MG301 |
| I | GOL304 |
| I | HOH401 |
| I | HOH402 |
| I | HOH427 |
| I | HOH461 |
| I | HOH497 |
| site_id | EC5 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE GOL I 304 |
| Chain | Residue |
| I | ARG34 |
| I | VAL36 |
| I | ASN37 |
| I | LEU77 |
| I | GLU81 |
| I | TYR256 |
| I | ARG260 |
| I | LEU265 |
| I | MG301 |
| I | GST303 |
| I | HOH401 |
| I | HOH402 |
| site_id | EC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG J 301 |
| Chain | Residue |
| J | ASN37 |
| J | GST303 |
| J | HOH401 |
| J | HOH402 |
| J | HOH403 |
| site_id | EC7 |
| Number of Residues | 22 |
| Details | BINDING SITE FOR RESIDUE SAH J 302 |
| Chain | Residue |
| J | GLN22 |
| J | TRP29 |
| J | HIS49 |
| J | HIS50 |
| J | GLY105 |
| J | GLY107 |
| J | THR127 |
| J | LEU128 |
| J | GLN132 |
| J | CYS154 |
| J | ASN155 |
| J | MET156 |
| J | ASN172 |
| J | GLU173 |
| J | SER174 |
| J | TYR177 |
| J | VAL178 |
| J | HOH449 |
| J | HOH450 |
| J | HOH451 |
| J | HOH452 |
| J | HOH453 |
| site_id | EC8 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE GST J 303 |
| Chain | Residue |
| J | TRP29 |
| J | ARG34 |
| J | VAL36 |
| J | ASN37 |
| J | HIS49 |
| J | HIS50 |
| J | TYR51 |
| J | TYR177 |
| J | PHE222 |
| J | ARG260 |
| J | PHE282 |
| J | MG301 |
| J | HOH401 |
| J | HOH402 |
| J | HOH403 |
| J | HOH479 |
| site_id | EC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL J 304 |
| Chain | Residue |
| J | ASP179 |
| J | LEU180 |
| J | HIS181 |
| J | HIS227 |
| J | GLU231 |
| J | HOH531 |
| site_id | FC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG K 301 |
| Chain | Residue |
| K | ASN37 |
| K | GST303 |
| K | HOH401 |
| K | HOH402 |
| K | HOH403 |
| site_id | FC2 |
| Number of Residues | 22 |
| Details | BINDING SITE FOR RESIDUE SAH K 302 |
| Chain | Residue |
| K | GLN22 |
| K | TRP29 |
| K | HIS48 |
| K | HIS49 |
| K | HIS50 |
| K | GLY105 |
| K | GLY107 |
| K | THR127 |
| K | LEU128 |
| K | GLN132 |
| K | CYS154 |
| K | ASN155 |
| K | MET156 |
| K | ASN172 |
| K | SER174 |
| K | TYR177 |
| K | VAL178 |
| K | HOH439 |
| K | HOH444 |
| K | HOH468 |
| K | HOH476 |
| K | HOH486 |
| site_id | FC3 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE GST K 303 |
| Chain | Residue |
| K | TRP29 |
| K | ARG34 |
| K | VAL36 |
| K | ASN37 |
| K | HIS49 |
| K | HIS50 |
| K | TYR51 |
| K | TYR177 |
| K | GLY202 |
| K | PHE222 |
| K | ARG260 |
| K | PHE282 |
| K | MG301 |
| K | HOH401 |
| K | HOH402 |
| K | HOH403 |
| K | HOH442 |
| site_id | FC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG L 301 |
| Chain | Residue |
| L | ASN37 |
| L | GST303 |
| L | HOH401 |
| L | HOH402 |
| L | HOH403 |
| site_id | FC5 |
| Number of Residues | 22 |
| Details | BINDING SITE FOR RESIDUE SAH L 302 |
| Chain | Residue |
| L | GLN22 |
| L | TRP29 |
| L | HIS49 |
| L | HIS50 |
| L | GLY105 |
| L | GLY107 |
| L | THR127 |
| L | LEU128 |
| L | GLN132 |
| L | CYS154 |
| L | ASN155 |
| L | MET156 |
| L | ASN172 |
| L | GLU173 |
| L | SER174 |
| L | TYR177 |
| L | VAL178 |
| L | HOH442 |
| L | HOH443 |
| L | HOH445 |
| L | HOH450 |
| L | HOH451 |
| site_id | FC6 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE GST L 303 |
| Chain | Residue |
| L | TRP29 |
| L | ARG34 |
| L | VAL36 |
| L | ASN37 |
| L | HIS49 |
| L | HIS50 |
| L | TYR51 |
| L | TYR177 |
| L | GLY202 |
| L | PHE222 |
| L | ARG260 |
| L | PHE282 |
| L | MG301 |
| L | HOH401 |
| L | HOH403 |
| L | HOH456 |
| site_id | FC7 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL L 304 |
| Chain | Residue |
| L | ASP179 |
| L | LEU180 |
| L | HIS181 |
| L | HIS227 |
| L | GLU231 |
| L | HOH501 |
| L | HOH513 |
