3VAV

Crystal structure of 3-methyl-2-oxobutanoate hydroxymethyltransferase from Burkholderia thailandensis

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000287	molecular_function	magnesium ion binding
A	0003864	molecular_function	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
A	0005737	cellular_component	cytoplasm
A	0015940	biological_process	pantothenate biosynthetic process
B	0000287	molecular_function	magnesium ion binding
B	0003864	molecular_function	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
B	0005737	cellular_component	cytoplasm
B	0015940	biological_process	pantothenate biosynthetic process
C	0000287	molecular_function	magnesium ion binding
C	0003864	molecular_function	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
C	0005737	cellular_component	cytoplasm
C	0015940	biological_process	pantothenate biosynthetic process
D	0000287	molecular_function	magnesium ion binding
D	0003864	molecular_function	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
D	0005737	cellular_component	cytoplasm
D	0015940	biological_process	pantothenate biosynthetic process
E	0000287	molecular_function	magnesium ion binding
E	0003864	molecular_function	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
E	0005737	cellular_component	cytoplasm
E	0015940	biological_process	pantothenate biosynthetic process
F	0000287	molecular_function	magnesium ion binding
F	0003864	molecular_function	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
F	0005737	cellular_component	cytoplasm
F	0015940	biological_process	pantothenate biosynthetic process
G	0000287	molecular_function	magnesium ion binding
G	0003864	molecular_function	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
G	0005737	cellular_component	cytoplasm
G	0015940	biological_process	pantothenate biosynthetic process
H	0000287	molecular_function	magnesium ion binding
H	0003864	molecular_function	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
H	0005737	cellular_component	cytoplasm
H	0015940	biological_process	pantothenate biosynthetic process
I	0000287	molecular_function	magnesium ion binding
I	0003864	molecular_function	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
I	0005737	cellular_component	cytoplasm
I	0015940	biological_process	pantothenate biosynthetic process
J	0000287	molecular_function	magnesium ion binding
J	0003864	molecular_function	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
J	0005737	cellular_component	cytoplasm
J	0015940	biological_process	pantothenate biosynthetic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE EDO A 272

Chain	Residue
A	ASP71
A	ASP72
A	TYR75
A	HOH762
F	TYR75

---

site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE EDO B 272

Chain	Residue
B	TYR75
B	ARG82
G	GLN60
G	HOH452

---

site_id	AC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE EDO C 272

Chain	Residue
C	LYS120
C	HIS144
C	VAL222
C	HOH286
C	HOH465
C	HOH1168

---

site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE EDO D 272

Chain	Residue
D	TYR75
D	ALA78
D	ARG82
I	HOH296

---

site_id	AC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE EDO E 272

Chain	Residue
E	LYS120
E	HIS144
E	HOH433
E	HOH751

---

site_id	AC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE EDO G 272

Chain	Residue
B	GLN60
G	ARG82
G	HOH281
G	HOH295

---

site_id	AC7
Number of Residues	6
Details	BINDING SITE FOR RESIDUE EDO G 273

Chain	Residue
G	LYS120
G	HIS144
G	VAL222
G	HOH282
G	HOH1183
G	HOH1692

---

site_id	AC8
Number of Residues	3
Details	BINDING SITE FOR RESIDUE EDO H 272

Chain	Residue
C	GLN60
H	ARG82
H	HOH331

---

site_id	AC9
Number of Residues	4
Details	BINDING SITE FOR RESIDUE EDO I 272

Chain	Residue
I	LYS120
I	HIS144
I	HOH279
I	HOH1195

---

site_id	BC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CL I 273

Chain	Residue
D	HOH648
I	HOH1794

---

site_id	BC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE EDO J 272

Chain	Residue
E	GLN60
J	TYR75
J	ARG82
J	HOH457

---

site_id	BC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE EDO J 273

Chain	Residue
J	LYS120
J	HOH289
J	HOH1906
J	HOH2469

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	10
Details	Active site: {"description":"Proton acceptor","evidences":[{"source":"HAMAP-Rule","id":"MF_00156","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	50
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00156","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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