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3VAM

Structure of U2AF65 variant with BrU5C2 DNA

Functional Information from GO Data
ChainGOidnamespacecontents
A0003676molecular_functionnucleic acid binding
A0003723molecular_functionRNA binding
B0003676molecular_functionnucleic acid binding
B0003723molecular_functionRNA binding
Functional Information from PDB Data
site_idAC1
Number of Residues5
DetailsBINDING SITE FOR RESIDUE DIO A 401
ChainResidue
ATYR269
AASN271
AGLY297
ALEU298
ASER299

site_idAC2
Number of Residues4
DetailsBINDING SITE FOR RESIDUE DIO A 402
ChainResidue
APRO144
AALA148
AGLN233
ALEU325

site_idAC3
Number of Residues2
DetailsBINDING SITE FOR RESIDUE SO4 A 403
ChainResidue
ALYS225
AARG227

site_idAC4
Number of Residues4
DetailsBINDING SITE FOR RESIDUE SO4 A 404
ChainResidue
AGLN190
AILE191
AASN192
AHOH535

site_idAC5
Number of Residues3
DetailsBINDING SITE FOR RESIDUE GOL A 405
ChainResidue
AASN192
AGLN193
AASP194

site_idAC6
Number of Residues2
DetailsBINDING SITE FOR RESIDUE CPQ B 401
ChainResidue
BTYR269
BGLN274

site_idAC7
Number of Residues3
DetailsBINDING SITE FOR RESIDUE DIO B 402
ChainResidue
BLYS276
BLEU285
BLYS286

site_idAC8
Number of Residues2
DetailsBINDING SITE FOR RESIDUE DIO B 403
ChainResidue
BARG174
BHIS259

site_idAC9
Number of Residues5
DetailsBINDING SITE FOR RESIDUE DIO B 404
ChainResidue
BASN268
BTYR269
BASN271
BLEU298
BSER299

site_idBC1
Number of Residues3
DetailsBINDING SITE FOR RESIDUE SO4 B 405
ChainResidue
BARG149
BSER204
BVAL205

site_idBC2
Number of Residues4
DetailsBINDING SITE FOR RESIDUE SO4 B 406
ChainResidue
AARG174
BLYS225
BARG227
BHOH550

site_idBC3
Number of Residues2
DetailsBINDING SITE FOR RESIDUE SO4 B 407
ChainResidue
BARG228
BTYR232

site_idBC4
Number of Residues3
DetailsBINDING SITE FOR RESIDUE GOL B 408
ChainResidue
BALA181
BGLN333
BARG334

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues2
DetailsMOD_RES: 5-hydroxylysine; by JMJD6 => ECO:0000269|PubMed:19574390
ChainResidueDetails
ALYS276
BLYS276

site_idSWS_FT_FI2
Number of Residues2
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163
ChainResidueDetails
ASER294
BSER294

227344

PDB entries from 2024-11-13

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