3V93
unliganded structure of TcrPDEC1 catalytic domain
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004114 | molecular_function | 3',5'-cyclic-nucleotide phosphodiesterase activity |
| A | 0007165 | biological_process | signal transduction |
| A | 0008081 | molecular_function | phosphoric diester hydrolase activity |
| B | 0004114 | molecular_function | 3',5'-cyclic-nucleotide phosphodiesterase activity |
| B | 0007165 | biological_process | signal transduction |
| B | 0008081 | molecular_function | phosphoric diester hydrolase activity |
| C | 0004114 | molecular_function | 3',5'-cyclic-nucleotide phosphodiesterase activity |
| C | 0007165 | biological_process | signal transduction |
| C | 0008081 | molecular_function | phosphoric diester hydrolase activity |
| D | 0004114 | molecular_function | 3',5'-cyclic-nucleotide phosphodiesterase activity |
| D | 0007165 | biological_process | signal transduction |
| D | 0008081 | molecular_function | phosphoric diester hydrolase activity |
| E | 0004114 | molecular_function | 3',5'-cyclic-nucleotide phosphodiesterase activity |
| E | 0007165 | biological_process | signal transduction |
| E | 0008081 | molecular_function | phosphoric diester hydrolase activity |
| F | 0004114 | molecular_function | 3',5'-cyclic-nucleotide phosphodiesterase activity |
| F | 0007165 | biological_process | signal transduction |
| F | 0008081 | molecular_function | phosphoric diester hydrolase activity |
| G | 0004114 | molecular_function | 3',5'-cyclic-nucleotide phosphodiesterase activity |
| G | 0007165 | biological_process | signal transduction |
| G | 0008081 | molecular_function | phosphoric diester hydrolase activity |
| H | 0004114 | molecular_function | 3',5'-cyclic-nucleotide phosphodiesterase activity |
| H | 0007165 | biological_process | signal transduction |
| H | 0008081 | molecular_function | phosphoric diester hydrolase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE ZN A 701 |
| Chain | Residue |
| A | HIS372 |
| A | HIS409 |
| A | ASP410 |
| A | ASP521 |
| A | MG702 |
| A | HOH801 |
| A | HOH802 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE MG A 702 |
| Chain | Residue |
| A | HOH801 |
| A | HOH803 |
| A | HOH804 |
| A | HOH805 |
| A | HOH806 |
| A | ASP410 |
| A | ZN701 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE ZN B 701 |
| Chain | Residue |
| B | HIS372 |
| B | HIS409 |
| B | ASP410 |
| B | ASP521 |
| B | MG702 |
| B | HOH801 |
| B | HOH802 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE MG B 702 |
| Chain | Residue |
| B | ASP410 |
| B | ZN701 |
| B | HOH801 |
| B | HOH803 |
| B | HOH804 |
| B | HOH805 |
| B | HOH806 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE ZN C 701 |
| Chain | Residue |
| C | HIS372 |
| C | HIS409 |
| C | ASP410 |
| C | ASP521 |
| C | MG702 |
| C | HOH801 |
| C | HOH802 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE MG C 702 |
| Chain | Residue |
| C | ASP410 |
| C | ZN701 |
| C | HOH801 |
| C | HOH803 |
| C | HOH804 |
| C | HOH805 |
| C | HOH806 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ZN D 701 |
| Chain | Residue |
| D | HIS372 |
| D | HIS409 |
| D | ASP410 |
| D | ASP521 |
| D | HOH801 |
| D | HOH802 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG D 702 |
| Chain | Residue |
| D | ASP410 |
| D | HOH801 |
| D | HOH803 |
| D | HOH804 |
| D | HOH805 |
| D | HOH806 |
| site_id | AC9 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE ZN E 701 |
| Chain | Residue |
| E | HIS372 |
| E | HIS409 |
| E | ASP410 |
| E | ASP521 |
| E | MG702 |
| E | HOH801 |
| E | HOH802 |
| site_id | BC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE MG E 702 |
| Chain | Residue |
| E | ASP410 |
| E | ZN701 |
| E | HOH801 |
| E | HOH803 |
| E | HOH804 |
| E | HOH805 |
| E | HOH806 |
| site_id | BC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE ZN F 701 |
| Chain | Residue |
| F | HIS372 |
| F | HIS409 |
| F | ASP410 |
| F | ASP521 |
| F | MG702 |
| F | HOH801 |
| F | HOH802 |
| site_id | BC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE MG F 702 |
| Chain | Residue |
| F | ASP410 |
| F | ZN701 |
| F | HOH801 |
| F | HOH803 |
| F | HOH804 |
| F | HOH805 |
| F | HOH806 |
| site_id | BC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE ZN G 701 |
| Chain | Residue |
| G | HIS372 |
| G | HIS409 |
| G | ASP410 |
| G | ASP521 |
| G | MG702 |
| G | HOH801 |
| G | HOH802 |
| site_id | BC5 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE MG G 702 |
| Chain | Residue |
| G | ASP410 |
| G | ZN701 |
| G | HOH801 |
| G | HOH803 |
| G | HOH804 |
| G | HOH805 |
| G | HOH806 |
| site_id | BC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE ZN H 701 |
| Chain | Residue |
| H | ASP521 |
| H | MG702 |
| H | HOH801 |
| H | HOH802 |
| H | HIS372 |
| H | HIS409 |
| H | ASP410 |
| site_id | BC7 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE MG H 702 |
| Chain | Residue |
| H | ASP410 |
| H | ZN701 |
| H | HOH801 |
| H | HOH803 |
| H | HOH804 |
| H | HOH805 |
| H | HOH806 |
Functional Information from PROSITE/UniProt
| site_id | PS00126 |
| Number of Residues | 12 |
| Details | PDEASE_I_1 3'5'-cyclic nucleotide phosphodiesterase domain signature. HDVcHpGrtNaF |
| Chain | Residue | Details |
| A | HIS409-PHE420 |
