3V5R
Crystal structure of the unliganded form of Gal3p
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0000411 | biological_process | positive regulation of transcription by galactose |
| A | 0000435 | biological_process | positive regulation of transcription from RNA polymerase II promoter by galactose |
| A | 0004335 | molecular_function | galactokinase activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005634 | cellular_component | nucleus |
| A | 0005667 | cellular_component | transcription regulator complex |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0006012 | biological_process | galactose metabolic process |
| A | 0016301 | molecular_function | kinase activity |
| A | 0016773 | molecular_function | phosphotransferase activity, alcohol group as acceptor |
| A | 0045185 | biological_process | maintenance of protein location |
| A | 0045944 | biological_process | positive regulation of transcription by RNA polymerase II |
| A | 0046835 | biological_process | carbohydrate phosphorylation |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0000411 | biological_process | positive regulation of transcription by galactose |
| B | 0000435 | biological_process | positive regulation of transcription from RNA polymerase II promoter by galactose |
| B | 0004335 | molecular_function | galactokinase activity |
| B | 0005515 | molecular_function | protein binding |
| B | 0005524 | molecular_function | ATP binding |
| B | 0005634 | cellular_component | nucleus |
| B | 0005667 | cellular_component | transcription regulator complex |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0006012 | biological_process | galactose metabolic process |
| B | 0016301 | molecular_function | kinase activity |
| B | 0016773 | molecular_function | phosphotransferase activity, alcohol group as acceptor |
| B | 0045185 | biological_process | maintenance of protein location |
| B | 0045944 | biological_process | positive regulation of transcription by RNA polymerase II |
| B | 0046835 | biological_process | carbohydrate phosphorylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1 |
| Chain | Residue |
| A | ALA317 |
| A | HOH806 |
| A | GLN318 |
| A | ASP323 |
| A | ILE324 |
| A | ARG330 |
| A | HOH529 |
| A | HOH577 |
| A | HOH653 |
| A | HOH757 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 3 |
| Chain | Residue |
| A | SER186 |
| A | LYS187 |
| A | LYS292 |
| A | HOH671 |
| A | HOH890 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 A 4 |
| Chain | Residue |
| A | ARG47 |
| A | GLY159 |
| A | GLY160 |
| A | GLY161 |
| A | HOH531 |
| A | HOH643 |
| A | HOH895 |
| A | HOH896 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 A 7 |
| Chain | Residue |
| A | GLY180 |
| A | LYS181 |
| A | ASN182 |
| A | HOH600 |
| A | HOH751 |
| B | SER285 |
| B | ARG312 |
| site_id | AC5 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE SO4 A 8 |
| Chain | Residue |
| A | THR350 |
| A | VAL351 |
| A | HIS352 |
| A | ARG362 |
| A | HOH690 |
| A | HOH691 |
| B | VAL196 |
| B | HIS199 |
| B | TYR200 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 10 |
| Chain | Residue |
| A | LEU288 |
| A | ARG299 |
| A | GLY300 |
| A | HOH673 |
| A | HOH981 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 A 12 |
| Chain | Residue |
| A | ARG482 |
| A | HOH898 |
| A | HOH1027 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 14 |
| Chain | Residue |
| A | SER361 |
| A | ARG362 |
| A | HOH888 |
| B | ASN182 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 15 |
| Chain | Residue |
| A | ASN242 |
| A | HIS243 |
| A | THR410 |
| A | ASP411 |
| A | GLU412 |
| site_id | BC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 A 521 |
| Chain | Residue |
| A | PRO289 |
| A | SER290 |
| A | LYS292 |
| site_id | BC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 522 |
| Chain | Residue |
| A | HIS352 |
| A | ARG362 |
| B | LYS134 |
| B | SO4526 |
| B | HOH561 |
| site_id | BC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 A 523 |
| Chain | Residue |
| A | ALA136 |
| A | PRO137 |
| A | GLU138 |
| A | ARG139 |
| A | HOH566 |
| A | HOH725 |
| site_id | BC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 A 524 |
| Chain | Residue |
| A | LYS398 |
| A | MET402 |
| A | ARG420 |
| A | LEU421 |
| A | HOH659 |
| A | HOH1042 |
| site_id | BC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 A 525 |
| Chain | Residue |
| A | LYS134 |
| A | ARG192 |
| A | HOH660 |
| A | HOH941 |
| A | HOH1066 |
| B | SO4524 |
| site_id | BC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 B 2 |
| Chain | Residue |
| A | LYS134 |
| A | HOH939 |
| A | HOH942 |
| B | SER361 |
| B | ARG362 |
| B | SO4524 |
| B | HOH540 |
| site_id | BC7 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE SO4 B 5 |
| Chain | Residue |
| A | HIS126 |
| A | VAL196 |
| A | HIS199 |
| A | TYR200 |
| A | HOH999 |
| B | THR350 |
| B | VAL351 |
| B | HIS352 |
| B | ARG362 |
| B | HOH573 |
| site_id | BC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 B 6 |
| Chain | Residue |
| B | ARG299 |
| B | GLY300 |
| B | HOH574 |
| B | HOH626 |
| B | HOH737 |
| site_id | BC9 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 B 9 |
| Chain | Residue |
| B | ARG47 |
| B | GLY159 |
| B | GLY160 |
| B | GLY161 |
| B | LEU162 |
| B | HOH548 |
| B | HOH576 |
| B | HOH672 |
| site_id | CC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 B 11 |
| Chain | Residue |
| B | ARG482 |
| B | ILE506 |
| B | VAL508 |
| B | HOH571 |
| site_id | CC2 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 B 13 |
| Chain | Residue |
| B | PRO289 |
| B | SER290 |
| site_id | CC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 B 521 |
| Chain | Residue |
| B | GLY180 |
| B | LYS181 |
| B | HOH684 |
| B | HOH728 |
| site_id | CC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 B 522 |
| Chain | Residue |
| B | ILE324 |
| B | GLY325 |
| B | HOH529 |
| site_id | CC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 B 523 |
| Chain | Residue |
| B | LYS188 |
| B | LYS229 |
| B | HOH543 |
| site_id | CC6 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE SO4 B 524 |
| Chain | Residue |
| A | SO4525 |
| A | HOH941 |
| B | SO42 |
| B | HIS352 |
| B | ARG362 |
| B | HOH668 |
| B | HOH690 |
| B | HOH712 |
| B | HOH723 |
| site_id | CC7 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE SO4 B 525 |
| Chain | Residue |
| A | HIS352 |
| A | HOH691 |
| B | TYR107 |
| B | SER130 |
| B | LYS134 |
| B | HOH528 |
| B | HOH561 |
| B | HOH618 |
| B | HOH753 |
| site_id | CC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 B 526 |
| Chain | Residue |
| A | SO4522 |
| B | LYS134 |
| B | ASN182 |
| B | HOH596 |
| B | HOH728 |
| site_id | CC9 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 B 527 |
| Chain | Residue |
| B | SER186 |
| B | SER186 |
| B | LYS187 |
| B | LYS187 |
| B | HOH608 |
| B | HOH608 |
| B | HOH609 |
| B | HOH609 |
Functional Information from PROSITE/UniProt
| site_id | PS00106 |
| Number of Residues | 12 |
| Details | GALACTOKINASE Galactokinase signature. GRvNLIGEHiDY |
| Chain | Residue | Details |
| A | GLY46-TYR57 |
