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3V5I

The crystal structure of the mutant ClpP S98A (Staphylococcus aureus)

Functional Information from GO Data
ChainGOidnamespacecontents
A0004176molecular_functionATP-dependent peptidase activity
A0004252molecular_functionserine-type endopeptidase activity
A0005737cellular_componentcytoplasm
A0006508biological_processproteolysis
A0006515biological_processprotein quality control for misfolded or incompletely synthesized proteins
A0008233molecular_functionpeptidase activity
A0008236molecular_functionserine-type peptidase activity
A0009368cellular_componentendopeptidase Clp complex
A0016787molecular_functionhydrolase activity
A0051117molecular_functionATPase binding
B0004176molecular_functionATP-dependent peptidase activity
B0004252molecular_functionserine-type endopeptidase activity
B0005737cellular_componentcytoplasm
B0006508biological_processproteolysis
B0006515biological_processprotein quality control for misfolded or incompletely synthesized proteins
B0008233molecular_functionpeptidase activity
B0008236molecular_functionserine-type peptidase activity
B0009368cellular_componentendopeptidase Clp complex
B0016787molecular_functionhydrolase activity
B0051117molecular_functionATPase binding
C0004176molecular_functionATP-dependent peptidase activity
C0004252molecular_functionserine-type endopeptidase activity
C0005737cellular_componentcytoplasm
C0006508biological_processproteolysis
C0006515biological_processprotein quality control for misfolded or incompletely synthesized proteins
C0008233molecular_functionpeptidase activity
C0008236molecular_functionserine-type peptidase activity
C0009368cellular_componentendopeptidase Clp complex
C0016787molecular_functionhydrolase activity
C0051117molecular_functionATPase binding
D0004176molecular_functionATP-dependent peptidase activity
D0004252molecular_functionserine-type endopeptidase activity
D0005737cellular_componentcytoplasm
D0006508biological_processproteolysis
D0006515biological_processprotein quality control for misfolded or incompletely synthesized proteins
D0008233molecular_functionpeptidase activity
D0008236molecular_functionserine-type peptidase activity
D0009368cellular_componentendopeptidase Clp complex
D0016787molecular_functionhydrolase activity
D0051117molecular_functionATPase binding
E0004176molecular_functionATP-dependent peptidase activity
E0004252molecular_functionserine-type endopeptidase activity
E0005737cellular_componentcytoplasm
E0006508biological_processproteolysis
E0006515biological_processprotein quality control for misfolded or incompletely synthesized proteins
E0008233molecular_functionpeptidase activity
E0008236molecular_functionserine-type peptidase activity
E0009368cellular_componentendopeptidase Clp complex
E0016787molecular_functionhydrolase activity
E0051117molecular_functionATPase binding
F0004176molecular_functionATP-dependent peptidase activity
F0004252molecular_functionserine-type endopeptidase activity
F0005737cellular_componentcytoplasm
F0006508biological_processproteolysis
F0006515biological_processprotein quality control for misfolded or incompletely synthesized proteins
F0008233molecular_functionpeptidase activity
F0008236molecular_functionserine-type peptidase activity
F0009368cellular_componentendopeptidase Clp complex
F0016787molecular_functionhydrolase activity
F0051117molecular_functionATPase binding
G0004176molecular_functionATP-dependent peptidase activity
G0004252molecular_functionserine-type endopeptidase activity
G0005737cellular_componentcytoplasm
G0006508biological_processproteolysis
G0006515biological_processprotein quality control for misfolded or incompletely synthesized proteins
G0008233molecular_functionpeptidase activity
G0008236molecular_functionserine-type peptidase activity
G0009368cellular_componentendopeptidase Clp complex
G0016787molecular_functionhydrolase activity
G0051117molecular_functionATPase binding
H0004176molecular_functionATP-dependent peptidase activity
H0004252molecular_functionserine-type endopeptidase activity
H0005737cellular_componentcytoplasm
H0006508biological_processproteolysis
H0006515biological_processprotein quality control for misfolded or incompletely synthesized proteins
H0008233molecular_functionpeptidase activity
H0008236molecular_functionserine-type peptidase activity
H0009368cellular_componentendopeptidase Clp complex
H0016787molecular_functionhydrolase activity
H0051117molecular_functionATPase binding
I0004176molecular_functionATP-dependent peptidase activity
I0004252molecular_functionserine-type endopeptidase activity
I0005737cellular_componentcytoplasm
I0006508biological_processproteolysis
I0006515biological_processprotein quality control for misfolded or incompletely synthesized proteins
I0008233molecular_functionpeptidase activity
I0008236molecular_functionserine-type peptidase activity
I0009368cellular_componentendopeptidase Clp complex
I0016787molecular_functionhydrolase activity
I0051117molecular_functionATPase binding
J0004176molecular_functionATP-dependent peptidase activity
J0004252molecular_functionserine-type endopeptidase activity
J0005737cellular_componentcytoplasm
J0006508biological_processproteolysis
J0006515biological_processprotein quality control for misfolded or incompletely synthesized proteins
J0008233molecular_functionpeptidase activity
J0008236molecular_functionserine-type peptidase activity
J0009368cellular_componentendopeptidase Clp complex
J0016787molecular_functionhydrolase activity
J0051117molecular_functionATPase binding
K0004176molecular_functionATP-dependent peptidase activity
K0004252molecular_functionserine-type endopeptidase activity
K0005737cellular_componentcytoplasm
K0006508biological_processproteolysis
K0006515biological_processprotein quality control for misfolded or incompletely synthesized proteins
K0008233molecular_functionpeptidase activity
K0008236molecular_functionserine-type peptidase activity
K0009368cellular_componentendopeptidase Clp complex
K0016787molecular_functionhydrolase activity
K0051117molecular_functionATPase binding
L0004176molecular_functionATP-dependent peptidase activity
L0004252molecular_functionserine-type endopeptidase activity
L0005737cellular_componentcytoplasm
L0006508biological_processproteolysis
L0006515biological_processprotein quality control for misfolded or incompletely synthesized proteins
L0008233molecular_functionpeptidase activity
L0008236molecular_functionserine-type peptidase activity
L0009368cellular_componentendopeptidase Clp complex
L0016787molecular_functionhydrolase activity
L0051117molecular_functionATPase binding
M0004176molecular_functionATP-dependent peptidase activity
M0004252molecular_functionserine-type endopeptidase activity
M0005737cellular_componentcytoplasm
M0006508biological_processproteolysis
M0006515biological_processprotein quality control for misfolded or incompletely synthesized proteins
M0008233molecular_functionpeptidase activity
M0008236molecular_functionserine-type peptidase activity
M0009368cellular_componentendopeptidase Clp complex
M0016787molecular_functionhydrolase activity
M0051117molecular_functionATPase binding
N0004176molecular_functionATP-dependent peptidase activity
N0004252molecular_functionserine-type endopeptidase activity
N0005737cellular_componentcytoplasm
N0006508biological_processproteolysis
N0006515biological_processprotein quality control for misfolded or incompletely synthesized proteins
N0008233molecular_functionpeptidase activity
N0008236molecular_functionserine-type peptidase activity
N0009368cellular_componentendopeptidase Clp complex
N0016787molecular_functionhydrolase activity
N0051117molecular_functionATPase binding
O0004176molecular_functionATP-dependent peptidase activity
O0004252molecular_functionserine-type endopeptidase activity
O0005737cellular_componentcytoplasm
O0006508biological_processproteolysis
O0006515biological_processprotein quality control for misfolded or incompletely synthesized proteins
O0008233molecular_functionpeptidase activity
O0008236molecular_functionserine-type peptidase activity
O0009368cellular_componentendopeptidase Clp complex
O0016787molecular_functionhydrolase activity
O0051117molecular_functionATPase binding
P0004176molecular_functionATP-dependent peptidase activity
P0004252molecular_functionserine-type endopeptidase activity
P0005737cellular_componentcytoplasm
P0006508biological_processproteolysis
P0006515biological_processprotein quality control for misfolded or incompletely synthesized proteins
P0008233molecular_functionpeptidase activity
P0008236molecular_functionserine-type peptidase activity
P0009368cellular_componentendopeptidase Clp complex
P0016787molecular_functionhydrolase activity
P0051117molecular_functionATPase binding
Q0004176molecular_functionATP-dependent peptidase activity
Q0004252molecular_functionserine-type endopeptidase activity
Q0005737cellular_componentcytoplasm
Q0006508biological_processproteolysis
Q0006515biological_processprotein quality control for misfolded or incompletely synthesized proteins
Q0008233molecular_functionpeptidase activity
Q0008236molecular_functionserine-type peptidase activity
Q0009368cellular_componentendopeptidase Clp complex
Q0016787molecular_functionhydrolase activity
Q0051117molecular_functionATPase binding
R0004176molecular_functionATP-dependent peptidase activity
R0004252molecular_functionserine-type endopeptidase activity
R0005737cellular_componentcytoplasm
R0006508biological_processproteolysis
R0006515biological_processprotein quality control for misfolded or incompletely synthesized proteins
R0008233molecular_functionpeptidase activity
R0008236molecular_functionserine-type peptidase activity
R0009368cellular_componentendopeptidase Clp complex
R0016787molecular_functionhydrolase activity
R0051117molecular_functionATPase binding
S0004176molecular_functionATP-dependent peptidase activity
S0004252molecular_functionserine-type endopeptidase activity
S0005737cellular_componentcytoplasm
S0006508biological_processproteolysis
S0006515biological_processprotein quality control for misfolded or incompletely synthesized proteins
S0008233molecular_functionpeptidase activity
S0008236molecular_functionserine-type peptidase activity
S0009368cellular_componentendopeptidase Clp complex
S0016787molecular_functionhydrolase activity
S0051117molecular_functionATPase binding
T0004176molecular_functionATP-dependent peptidase activity
T0004252molecular_functionserine-type endopeptidase activity
T0005737cellular_componentcytoplasm
T0006508biological_processproteolysis
T0006515biological_processprotein quality control for misfolded or incompletely synthesized proteins
T0008233molecular_functionpeptidase activity
T0008236molecular_functionserine-type peptidase activity
T0009368cellular_componentendopeptidase Clp complex
T0016787molecular_functionhydrolase activity
T0051117molecular_functionATPase binding
U0004176molecular_functionATP-dependent peptidase activity
U0004252molecular_functionserine-type endopeptidase activity
U0005737cellular_componentcytoplasm
U0006508biological_processproteolysis
U0006515biological_processprotein quality control for misfolded or incompletely synthesized proteins
U0008233molecular_functionpeptidase activity
U0008236molecular_functionserine-type peptidase activity
U0009368cellular_componentendopeptidase Clp complex
U0016787molecular_functionhydrolase activity
U0051117molecular_functionATPase binding
V0004176molecular_functionATP-dependent peptidase activity
V0004252molecular_functionserine-type endopeptidase activity
V0005737cellular_componentcytoplasm
V0006508biological_processproteolysis
V0006515biological_processprotein quality control for misfolded or incompletely synthesized proteins
V0008233molecular_functionpeptidase activity
V0008236molecular_functionserine-type peptidase activity
V0009368cellular_componentendopeptidase Clp complex
V0016787molecular_functionhydrolase activity
V0051117molecular_functionATPase binding
W0004176molecular_functionATP-dependent peptidase activity
W0004252molecular_functionserine-type endopeptidase activity
W0005737cellular_componentcytoplasm
W0006508biological_processproteolysis
W0006515biological_processprotein quality control for misfolded or incompletely synthesized proteins
W0008233molecular_functionpeptidase activity
W0008236molecular_functionserine-type peptidase activity
W0009368cellular_componentendopeptidase Clp complex
W0016787molecular_functionhydrolase activity
W0051117molecular_functionATPase binding
X0004176molecular_functionATP-dependent peptidase activity
X0004252molecular_functionserine-type endopeptidase activity
X0005737cellular_componentcytoplasm
X0006508biological_processproteolysis
X0006515biological_processprotein quality control for misfolded or incompletely synthesized proteins
X0008233molecular_functionpeptidase activity
X0008236molecular_functionserine-type peptidase activity
X0009368cellular_componentendopeptidase Clp complex
X0016787molecular_functionhydrolase activity
X0051117molecular_functionATPase binding
Y0004176molecular_functionATP-dependent peptidase activity
Y0004252molecular_functionserine-type endopeptidase activity
Y0005737cellular_componentcytoplasm
Y0006508biological_processproteolysis
Y0006515biological_processprotein quality control for misfolded or incompletely synthesized proteins
Y0008233molecular_functionpeptidase activity
Y0008236molecular_functionserine-type peptidase activity
Y0009368cellular_componentendopeptidase Clp complex
Y0016787molecular_functionhydrolase activity
Y0051117molecular_functionATPase binding
Z0004176molecular_functionATP-dependent peptidase activity
Z0004252molecular_functionserine-type endopeptidase activity
Z0005737cellular_componentcytoplasm
Z0006508biological_processproteolysis
Z0006515biological_processprotein quality control for misfolded or incompletely synthesized proteins
Z0008233molecular_functionpeptidase activity
Z0008236molecular_functionserine-type peptidase activity
Z0009368cellular_componentendopeptidase Clp complex
Z0016787molecular_functionhydrolase activity
Z0051117molecular_functionATPase binding
a0004176molecular_functionATP-dependent peptidase activity
a0004252molecular_functionserine-type endopeptidase activity
a0005737cellular_componentcytoplasm
a0006508biological_processproteolysis
a0006515biological_processprotein quality control for misfolded or incompletely synthesized proteins
a0008233molecular_functionpeptidase activity
a0008236molecular_functionserine-type peptidase activity
a0009368cellular_componentendopeptidase Clp complex
a0016787molecular_functionhydrolase activity
a0051117molecular_functionATPase binding
b0004176molecular_functionATP-dependent peptidase activity
b0004252molecular_functionserine-type endopeptidase activity
b0005737cellular_componentcytoplasm
b0006508biological_processproteolysis
b0006515biological_processprotein quality control for misfolded or incompletely synthesized proteins
b0008233molecular_functionpeptidase activity
b0008236molecular_functionserine-type peptidase activity
b0009368cellular_componentendopeptidase Clp complex
b0016787molecular_functionhydrolase activity
b0051117molecular_functionATPase binding
Functional Information from PROSITE/UniProt
site_idPS00382
Number of Residues14
DetailsCLP_PROTEASE_HIS Endopeptidase Clp histidine active site. RfalPnaeVMIHQP
ChainResidueDetails
AARG112-PRO125

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues28
DetailsACT_SITE: Nucleophile => ECO:0000255|HAMAP-Rule:MF_00444
ChainResidueDetails
AALA98
JALA98
KALA98
LALA98
MALA98
NALA98
OALA98
PALA98
QALA98
RALA98
SALA98
BALA98
TALA98
UALA98
VALA98
WALA98
XALA98
YALA98
ZALA98
aALA98
bALA98
CALA98
DALA98
EALA98
FALA98
GALA98
HALA98
IALA98

site_idSWS_FT_FI2
Number of Residues28
DetailsACT_SITE: ACT_SITE => ECO:0000255|HAMAP-Rule:MF_00444
ChainResidueDetails
AHIS123
JHIS123
KHIS123
LHIS123
MHIS123
NHIS123
OHIS123
PHIS123
QHIS123
RHIS123
SHIS123
BHIS123
THIS123
UHIS123
VHIS123
WHIS123
XHIS123
YHIS123
ZHIS123
aHIS123
bHIS123
CHIS123
DHIS123
EHIS123
FHIS123
GHIS123
HHIS123
IHIS123

218853

PDB entries from 2024-04-24

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