3V1W
Molecular Basis for Multiple Ligand Binding of Calsequestrin and Potential Inhibition by Caffeine and Gallocatecin
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000287 | molecular_function | magnesium ion binding |
| A | 0005509 | molecular_function | calcium ion binding |
| A | 0005759 | cellular_component | mitochondrial matrix |
| A | 0005783 | cellular_component | endoplasmic reticulum |
| A | 0014809 | biological_process | regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion |
| A | 0016529 | cellular_component | sarcoplasmic reticulum |
| A | 0030018 | cellular_component | Z disc |
| A | 0030955 | molecular_function | potassium ion binding |
| A | 0033017 | cellular_component | sarcoplasmic reticulum membrane |
| A | 0033018 | cellular_component | sarcoplasmic reticulum lumen |
| A | 0042803 | molecular_function | protein homodimerization activity |
| A | 0045214 | biological_process | sarcomere organization |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0051258 | biological_process | protein polymerization |
| A | 0051279 | biological_process | regulation of release of sequestered calcium ion into cytosol |
| A | 0051281 | biological_process | positive regulation of release of sequestered calcium ion into cytosol |
| A | 1901341 | biological_process | positive regulation of store-operated calcium channel activity |
| A | 2001256 | biological_process | regulation of store-operated calcium entry |
Functional Information from PROSITE/UniProt
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"UniProtKB","id":"P19633","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"P19633","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"UniProtKB","id":"P19633","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"22170046","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
