Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004175 | molecular_function | endopeptidase activity |
| A | 0004252 | molecular_function | serine-type endopeptidase activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005576 | cellular_component | extracellular region |
| A | 0005615 | cellular_component | extracellular space |
| A | 0006508 | biological_process | proteolysis |
| A | 0007586 | biological_process | digestion |
| A | 0008236 | molecular_function | serine-type peptidase activity |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0097180 | cellular_component | serine protease inhibitor complex |
| A | 0097655 | molecular_function | serpin family protein binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 480 |
| Chain | Residue |
| A | GLU70 |
| A | ASN72 |
| A | VAL75 |
| A | GLU80 |
| A | HOH1009 |
| A | HOH1013 |
| site_id | AC2 |
| Number of Residues | 22 |
| Details | BINDING SITE FOR RESIDUE 3YH A 481 |
| Chain | Residue |
| A | TYR184 |
| A | GLU186 |
| A | LYS188 |
| A | ASP189 |
| A | ALA190 |
| A | GLN192 |
| A | SER195 |
| A | TRP215 |
| A | GLY216 |
| A | GLY219 |
| A | CYS220 |
| A | GLY226 |
| A | HOH1004 |
| A | HOH1041 |
| A | HOH1086 |
| A | HOH1088 |
| A | HOH1090 |
| A | HOH1122 |
| A | HOH1158 |
| A | GLU97 |
| A | THR98 |
| A | PHE174 |
| site_id | AC3 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE SO4 A 482 |
| Chain | Residue |
| A | HIS57 |
| A | GLN135 |
| A | GLN192 |
| A | GLY193 |
| A | SER195 |
| A | IMD485 |
| A | HOH1140 |
| A | HOH1154 |
| A | HOH1221 |
| site_id | AC4 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 A 483 |
| Chain | Residue |
| A | TYR20 |
| A | THR21 |
| A | GOL486 |
| A | HOH1131 |
| A | HOH1139 |
| A | HOH1285 |
| A | HOH1384 |
| A | HOH1388 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 484 |
| Chain | Residue |
| A | ARG66 |
| A | HOH1153 |
| A | HOH1264 |
| A | HOH1278 |
| A | HOH1383 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE IMD A 485 |
| Chain | Residue |
| A | HIS57 |
| A | GLN135 |
| A | SO4482 |
| A | HOH1065 |
| site_id | AC7 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL A 486 |
| Chain | Residue |
| A | ILE16 |
| A | GLY18 |
| A | GLY19 |
| A | LYS156 |
| A | SO4483 |
| A | HOH1026 |
| A | HOH1378 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL A 487 |
| Chain | Residue |
| A | ASP153 |
| A | VAL154 |
| A | HOH1398 |
Functional Information from PROSITE/UniProt
| site_id | PS00134 |
| Number of Residues | 6 |
| Details | TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. VSAAHC |
| Chain | Residue | Details |
| A | VAL53-CYS58 | |
| site_id | PS00135 |
| Number of Residues | 12 |
| Details | TRYPSIN_SER Serine proteases, trypsin family, serine active site. DAcqGDSGGPVV |
| Chain | Residue | Details |
| A | ASP189-VAL200 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | ACT_SITE: Charge relay system |
| Chain | Residue | Details |
| A | HIS57 | |
| A | ASP102 | |
| A | SER195 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 7 |
| Details | BINDING: |
| Chain | Residue | Details |
| A | GLU70 | |
| A | ASN72 | |
| A | VAL75 | |
| A | GLU80 | |
| A | ASP189 | |
| A | GLN192 | |
| A | SER195 | |
