3V0B
3.9 angstrom crystal structure of BoNT/Ai in complex with NTNHA
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004222 | molecular_function | metalloendopeptidase activity |
A | 0005576 | cellular_component | extracellular region |
A | 0006508 | biological_process | proteolysis |
A | 0008237 | molecular_function | metallopeptidase activity |
A | 0008270 | molecular_function | zinc ion binding |
A | 0008320 | molecular_function | protein transmembrane transporter activity |
A | 0016020 | cellular_component | membrane |
A | 0020002 | cellular_component | host cell plasma membrane |
A | 0030430 | cellular_component | host cell cytoplasm |
A | 0035821 | biological_process | modulation of process of another organism |
A | 0044161 | cellular_component | host cell cytoplasmic vesicle |
A | 0044164 | cellular_component | host cell cytosol |
A | 0044221 | cellular_component | host cell synapse |
A | 0044231 | cellular_component | host cell presynaptic membrane |
A | 0046872 | molecular_function | metal ion binding |
A | 0071806 | biological_process | protein transmembrane transport |
A | 0090729 | molecular_function | toxin activity |
B | 0004222 | molecular_function | metalloendopeptidase activity |
B | 0005515 | molecular_function | protein binding |
B | 0005576 | cellular_component | extracellular region |
B | 0006508 | biological_process | proteolysis |
B | 0008270 | molecular_function | zinc ion binding |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE ZN A 1297 |
Chain | Residue |
A | HIS223 |
A | HIS227 |
A | GLU262 |
site_id | AC2 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE CA A 1298 |
Chain | Residue |
A | ALA575 |
A | ASN578 |
A | ARG581 |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 40 |
Details | TRANSMEM: Helical => ECO:0000255 |
Chain | Residue | Details |
A | ILE627-LEU647 | |
A | LEU656-LEU676 |
site_id | SWS_FT_FI2 |
Number of Residues | 1 |
Details | ACT_SITE: ACT_SITE => ECO:0000255|PROSITE-ProRule:PRU10095 |
Chain | Residue | Details |
A | GLN224 |
site_id | SWS_FT_FI3 |
Number of Residues | 2 |
Details | BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU10095, ECO:0000269|PubMed:17173035, ECO:0000305|PubMed:9783750, ECO:0007744|PDB:2NYY, ECO:0007744|PDB:2NZ9, ECO:0007744|PDB:3BTA, ECO:0007744|PDB:3QIX, ECO:0007744|PDB:3QIY, ECO:0007744|PDB:3QIZ, ECO:0007744|PDB:3QJ0 |
Chain | Residue | Details |
A | HIS223 | |
A | HIS227 |
site_id | SWS_FT_FI4 |
Number of Residues | 1 |
Details | BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU10095, ECO:0000269|PubMed:17173035, ECO:0007744|PDB:2NYY, ECO:0007744|PDB:2NZ9, ECO:0007744|PDB:3BTA, ECO:0007744|PDB:3QIX, ECO:0007744|PDB:3QIY, ECO:0007744|PDB:3QIZ, ECO:0007744|PDB:3QJ0 |
Chain | Residue | Details |
A | GLU262 |