3UTO
Twitchin kinase region from C.elegans (Fn31-NL-kin-CRD-Ig26)
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE GOL A 571 |
| Chain | Residue |
| A | ARG78 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PEG A 572 |
| Chain | Residue |
| A | ARG529 |
| A | TYR530 |
| A | ASP534 |
| A | HOH731 |
| B | VAL207 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE FLC A 573 |
| Chain | Residue |
| A | LYS561 |
| A | GLU563 |
| A | HOH668 |
| A | HOH711 |
| A | THR401 |
| A | PHE482 |
| A | LYS485 |
| site_id | AC4 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE P33 B 571 |
| Chain | Residue |
| A | GLU270 |
| A | ARG502 |
| A | ASN533 |
| A | ASP534 |
| B | GLU270 |
| B | ASN271 |
| B | ARG502 |
| B | ASN533 |
| B | ASP534 |
| B | HOH620 |
| B | HOH784 |
Functional Information from PROSITE/UniProt
| site_id | PS00107 |
| Number of Residues | 24 |
| Details | PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. LGTGAFGVVHrVteratgnn..........FAAK |
| Chain | Residue | Details |
| A | LEU162-LYS185 |
| site_id | PS00108 |
| Number of Residues | 13 |
| Details | PROTEIN_KINASE_ST Serine/Threonine protein kinases active-site signature. YvHlDLKpeNIMF |
| Chain | Residue | Details |
| A | TYR273-PHE285 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 510 |
| Details | Domain: {"description":"Protein kinase","evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 176 |
| Details | Domain: {"description":"Ig-like 17","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 128 |
| Details | Region: {"description":"C-terminal regulatory domain (CDR)","evidences":[{"source":"PubMed","id":"8202162","evidenceCode":"ECO:0000303"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"UniProtKB","id":"P28523","evidenceCode":"ECO:0000250"},{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"},{"source":"PROSITE-ProRule","id":"PRU10027","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 18 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"P28523","evidenceCode":"ECO:0000250"},{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
