Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

3UTH

Crystal structure of Aspergillus fumigatus UDP galactopyranose mutase complexed with substrate UDP-Galp in reduced state

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0008767	molecular_function	UDP-galactopyranose mutase activity
A	0016853	molecular_function	isomerase activity
A	0071555	biological_process	cell wall organization
B	0000166	molecular_function	nucleotide binding
B	0008767	molecular_function	UDP-galactopyranose mutase activity
B	0016853	molecular_function	isomerase activity
B	0071555	biological_process	cell wall organization
C	0000166	molecular_function	nucleotide binding
C	0008767	molecular_function	UDP-galactopyranose mutase activity
C	0016853	molecular_function	isomerase activity
C	0071555	biological_process	cell wall organization
D	0000166	molecular_function	nucleotide binding
D	0008767	molecular_function	UDP-galactopyranose mutase activity
D	0016853	molecular_function	isomerase activity
D	0071555	biological_process	cell wall organization

Functional Information from PDB Data

site_id	AC1
Number of Residues	29
Details	BINDING SITE FOR RESIDUE FDA A 511

Chain	Residue
A	GLY14
A	VAL60
A	GLY62
A	HIS63
A	VAL64
A	GLY240
A	VAL242
A	GLU373
A	GLY418
A	GLY446
A	ARG447
A	GLY16
A	GLY456
A	ASN457
A	GLN458
A	SER461
A	GDU514
A	HOH520
A	HOH528
A	HOH538
A	HOH573
A	HOH628
A	PRO17
A	THR18
A	ASP38
A	SER39
A	GLY45
A	LEU46
A	ALA47

site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 A 512

Chain	Residue
A	PRO307
A	GLU308
A	ARG309
A	LYS402
A	HOH544

site_id	AC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 A 513

Chain	Residue
A	LYS82
A	GLU83

site_id	AC4
Number of Residues	23
Details	BINDING SITE FOR RESIDUE GDU A 514

Chain	Residue
A	GLY62
A	PHE66
A	VAL95
A	TYR104
A	PHE106
A	GLN107
A	PHE158
A	MET159
A	ASN163
A	TRP167
A	ARG182
A	VAL183
A	ASN207
A	TRP315
A	TYR317
A	ARG327
A	TYR419
A	TYR453
A	ASN457
A	FDA511
A	HOH569
A	HOH585
A	HOH586

site_id	AC5
Number of Residues	31
Details	BINDING SITE FOR RESIDUE FDA B 511

Chain	Residue
B	GLY14
B	GLY16
B	PRO17
B	THR18
B	ASP38
B	SER39
B	GLY45
B	LEU46
B	ALA47
B	VAL60
B	GLY62
B	HIS63
B	VAL64
B	GLY240
B	VAL242
B	MET269
B	GLU373
B	GLY418
B	GLY446
B	ARG447
B	GLY456
B	ASN457
B	GLN458
B	SER461
B	GDU514
B	HOH555
B	HOH556
B	HOH557
B	HOH604
B	HOH621
B	HOH656

site_id	AC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 B 512

Chain	Residue
B	ASN40
B	ASP50
B	ARG413
B	HOH521

site_id	AC7
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 B 513

Chain	Residue
B	PRO307
B	GLU308
B	ARG309
B	LYS402
B	HOH570

site_id	AC8
Number of Residues	25
Details	BINDING SITE FOR RESIDUE GDU B 514

Chain	Residue
B	GLY62
B	PHE66
B	VAL95
B	TYR104
B	PHE106
B	GLN107
B	PHE158
B	MET159
B	ASN163
B	TRP167
B	ARG182
B	VAL183
B	ASN207
B	TRP315
B	TYR317
B	ARG327
B	TYR419
B	TYR453
B	ASN457
B	FDA511
B	HOH599
B	HOH633
B	HOH646
B	HOH647
B	HOH649

site_id	AC9
Number of Residues	29
Details	BINDING SITE FOR RESIDUE FDA C 511

Chain	Residue
C	GLY14
C	GLY16
C	PRO17
C	THR18
C	ASP38
C	SER39
C	GLY45
C	LEU46
C	ALA47
C	VAL60
C	GLY62
C	HIS63
C	VAL64
C	GLY240
C	VAL242
C	GLU373
C	GLY418
C	TYR419
C	GLY446
C	ARG447
C	GLY456
C	ASN457
C	GLN458
C	SER461
C	HOH534
C	HOH566
C	HOH603
C	HOH616
C	HOH675

site_id	BC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 C 512

Chain	Residue
C	PRO307
C	GLU308
C	ARG309
C	HOH529

site_id	BC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 C 513

Chain	Residue
C	ARG91
C	TYR104
C	ASN203
C	HOH545
C	HOH600

site_id	BC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 C 514

Chain	Residue
C	PRO114
C	LYS115
C	HOH578

site_id	BC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 C 515

Chain	Residue
C	ARG309
C	LYS402
C	ASP405
C	HOH664
C	HOH665

site_id	BC5
Number of Residues	28
Details	BINDING SITE FOR RESIDUE FDA D 511

Chain	Residue
D	GLY14
D	GLY16
D	PRO17
D	THR18
D	ASP38
D	SER39
D	GLY45
D	LEU46
D	ALA47
D	VAL60
D	GLY62
D	HIS63
D	VAL64
D	GLY240
D	VAL242
D	MET269
D	GLU373
D	GLY418
D	GLY446
D	ARG447
D	GLY456
D	ASN457
D	GLN458
D	SER461
D	HOH538
D	HOH579
D	HOH614
D	HOH653

site_id	BC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 D 512

Chain	Residue
D	PRO307
D	GLU308
D	ARG309
D	LYS402
D	HOH581

site_id	BC7
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 D 513

Chain	Residue
D	ARG306
D	ASP312

site_id	BC8
Number of Residues	6
Details	BINDING SITE FOR RESIDUE SO4 D 514

Chain	Residue
D	ARG91
D	TYR104
D	ASN203
D	HOH520
D	HOH584
D	HOH616

site_id	BC9
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 D 515

Chain	Residue
D	PRO114
D	LYS115
D	HOH583

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	32
Details	Binding site: {"evidences":[{"source":"PubMed","id":"22294687","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22334662","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3UKA","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3UKH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3UKK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3UKL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3UKP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3UTE","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"22334662","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3UKP","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI3
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"22334662","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3UKF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3UKP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3UKQ","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI4
Number of Residues	28
Details	Binding site: {"evidences":[{"source":"PubMed","id":"23036087","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5VWT","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI5
Number of Residues	32
Details	Binding site: {"evidences":[{"source":"PubMed","id":"22294687","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22334662","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3UKF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3UKH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3UKP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3UKQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3UTH","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI6
Number of Residues	8
Details	Binding site: {"evidences":[{"source":"PubMed","id":"22334662","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3UKH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3UKP","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI7
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"22294687","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22334662","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3UKH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3UKQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3UTH","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI8
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"22294687","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22334662","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3UKF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3UKH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3UTH","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI9
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"22334662","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3UKH","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)