3UTH
Crystal structure of Aspergillus fumigatus UDP galactopyranose mutase complexed with substrate UDP-Galp in reduced state
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0008767 | molecular_function | UDP-galactopyranose mutase activity |
| A | 0016853 | molecular_function | isomerase activity |
| A | 0071555 | biological_process | cell wall organization |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0008767 | molecular_function | UDP-galactopyranose mutase activity |
| B | 0016853 | molecular_function | isomerase activity |
| B | 0071555 | biological_process | cell wall organization |
| C | 0000166 | molecular_function | nucleotide binding |
| C | 0008767 | molecular_function | UDP-galactopyranose mutase activity |
| C | 0016853 | molecular_function | isomerase activity |
| C | 0071555 | biological_process | cell wall organization |
| D | 0000166 | molecular_function | nucleotide binding |
| D | 0008767 | molecular_function | UDP-galactopyranose mutase activity |
| D | 0016853 | molecular_function | isomerase activity |
| D | 0071555 | biological_process | cell wall organization |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 29 |
| Details | BINDING SITE FOR RESIDUE FDA A 511 |
| Chain | Residue |
| A | GLY14 |
| A | VAL60 |
| A | GLY62 |
| A | HIS63 |
| A | VAL64 |
| A | GLY240 |
| A | VAL242 |
| A | GLU373 |
| A | GLY418 |
| A | GLY446 |
| A | ARG447 |
| A | GLY16 |
| A | GLY456 |
| A | ASN457 |
| A | GLN458 |
| A | SER461 |
| A | GDU514 |
| A | HOH520 |
| A | HOH528 |
| A | HOH538 |
| A | HOH573 |
| A | HOH628 |
| A | PRO17 |
| A | THR18 |
| A | ASP38 |
| A | SER39 |
| A | GLY45 |
| A | LEU46 |
| A | ALA47 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 512 |
| Chain | Residue |
| A | PRO307 |
| A | GLU308 |
| A | ARG309 |
| A | LYS402 |
| A | HOH544 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 A 513 |
| Chain | Residue |
| A | LYS82 |
| A | GLU83 |
| site_id | AC4 |
| Number of Residues | 23 |
| Details | BINDING SITE FOR RESIDUE GDU A 514 |
| Chain | Residue |
| A | GLY62 |
| A | PHE66 |
| A | VAL95 |
| A | TYR104 |
| A | PHE106 |
| A | GLN107 |
| A | PHE158 |
| A | MET159 |
| A | ASN163 |
| A | TRP167 |
| A | ARG182 |
| A | VAL183 |
| A | ASN207 |
| A | TRP315 |
| A | TYR317 |
| A | ARG327 |
| A | TYR419 |
| A | TYR453 |
| A | ASN457 |
| A | FDA511 |
| A | HOH569 |
| A | HOH585 |
| A | HOH586 |
| site_id | AC5 |
| Number of Residues | 31 |
| Details | BINDING SITE FOR RESIDUE FDA B 511 |
| Chain | Residue |
| B | GLY14 |
| B | GLY16 |
| B | PRO17 |
| B | THR18 |
| B | ASP38 |
| B | SER39 |
| B | GLY45 |
| B | LEU46 |
| B | ALA47 |
| B | VAL60 |
| B | GLY62 |
| B | HIS63 |
| B | VAL64 |
| B | GLY240 |
| B | VAL242 |
| B | MET269 |
| B | GLU373 |
| B | GLY418 |
| B | GLY446 |
| B | ARG447 |
| B | GLY456 |
| B | ASN457 |
| B | GLN458 |
| B | SER461 |
| B | GDU514 |
| B | HOH555 |
| B | HOH556 |
| B | HOH557 |
| B | HOH604 |
| B | HOH621 |
| B | HOH656 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 B 512 |
| Chain | Residue |
| B | ASN40 |
| B | ASP50 |
| B | ARG413 |
| B | HOH521 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 B 513 |
| Chain | Residue |
| B | PRO307 |
| B | GLU308 |
| B | ARG309 |
| B | LYS402 |
| B | HOH570 |
| site_id | AC8 |
| Number of Residues | 25 |
| Details | BINDING SITE FOR RESIDUE GDU B 514 |
| Chain | Residue |
| B | GLY62 |
| B | PHE66 |
| B | VAL95 |
| B | TYR104 |
| B | PHE106 |
| B | GLN107 |
| B | PHE158 |
| B | MET159 |
| B | ASN163 |
| B | TRP167 |
| B | ARG182 |
| B | VAL183 |
| B | ASN207 |
| B | TRP315 |
| B | TYR317 |
| B | ARG327 |
| B | TYR419 |
| B | TYR453 |
| B | ASN457 |
| B | FDA511 |
| B | HOH599 |
| B | HOH633 |
| B | HOH646 |
| B | HOH647 |
| B | HOH649 |
| site_id | AC9 |
| Number of Residues | 29 |
| Details | BINDING SITE FOR RESIDUE FDA C 511 |
| Chain | Residue |
| C | GLY14 |
| C | GLY16 |
| C | PRO17 |
| C | THR18 |
| C | ASP38 |
| C | SER39 |
| C | GLY45 |
| C | LEU46 |
| C | ALA47 |
| C | VAL60 |
| C | GLY62 |
| C | HIS63 |
| C | VAL64 |
| C | GLY240 |
| C | VAL242 |
| C | GLU373 |
| C | GLY418 |
| C | TYR419 |
| C | GLY446 |
| C | ARG447 |
| C | GLY456 |
| C | ASN457 |
| C | GLN458 |
| C | SER461 |
| C | HOH534 |
| C | HOH566 |
| C | HOH603 |
| C | HOH616 |
| C | HOH675 |
| site_id | BC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 C 512 |
| Chain | Residue |
| C | PRO307 |
| C | GLU308 |
| C | ARG309 |
| C | HOH529 |
| site_id | BC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 C 513 |
| Chain | Residue |
| C | ARG91 |
| C | TYR104 |
| C | ASN203 |
| C | HOH545 |
| C | HOH600 |
| site_id | BC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 C 514 |
| Chain | Residue |
| C | PRO114 |
| C | LYS115 |
| C | HOH578 |
| site_id | BC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 C 515 |
| Chain | Residue |
| C | ARG309 |
| C | LYS402 |
| C | ASP405 |
| C | HOH664 |
| C | HOH665 |
| site_id | BC5 |
| Number of Residues | 28 |
| Details | BINDING SITE FOR RESIDUE FDA D 511 |
| Chain | Residue |
| D | GLY14 |
| D | GLY16 |
| D | PRO17 |
| D | THR18 |
| D | ASP38 |
| D | SER39 |
| D | GLY45 |
| D | LEU46 |
| D | ALA47 |
| D | VAL60 |
| D | GLY62 |
| D | HIS63 |
| D | VAL64 |
| D | GLY240 |
| D | VAL242 |
| D | MET269 |
| D | GLU373 |
| D | GLY418 |
| D | GLY446 |
| D | ARG447 |
| D | GLY456 |
| D | ASN457 |
| D | GLN458 |
| D | SER461 |
| D | HOH538 |
| D | HOH579 |
| D | HOH614 |
| D | HOH653 |
| site_id | BC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 D 512 |
| Chain | Residue |
| D | PRO307 |
| D | GLU308 |
| D | ARG309 |
| D | LYS402 |
| D | HOH581 |
| site_id | BC7 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 D 513 |
| Chain | Residue |
| D | ARG306 |
| D | ASP312 |
| site_id | BC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 D 514 |
| Chain | Residue |
| D | ARG91 |
| D | TYR104 |
| D | ASN203 |
| D | HOH520 |
| D | HOH584 |
| D | HOH616 |
| site_id | BC9 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 D 515 |
| Chain | Residue |
| D | PRO114 |
| D | LYS115 |
| D | HOH583 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 32 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:22294687, ECO:0000269|PubMed:22334662, ECO:0007744|PDB:3UKA, ECO:0007744|PDB:3UKH, ECO:0007744|PDB:3UKK, ECO:0007744|PDB:3UKL, ECO:0007744|PDB:3UKP, ECO:0007744|PDB:3UTE |
| Chain | Residue | Details |
| A | THR18 | |
| B | ASP38 | |
| B | LEU46 | |
| B | HIS63 | |
| B | VAL242 | |
| B | GLY456 | |
| B | GLN458 | |
| B | SER461 | |
| C | THR18 | |
| C | ASP38 | |
| C | LEU46 | |
| A | ASP38 | |
| C | HIS63 | |
| C | VAL242 | |
| C | GLY456 | |
| C | GLN458 | |
| C | SER461 | |
| D | THR18 | |
| D | ASP38 | |
| D | LEU46 | |
| D | HIS63 | |
| D | VAL242 | |
| A | LEU46 | |
| D | GLY456 | |
| D | GLN458 | |
| D | SER461 | |
| A | HIS63 | |
| A | VAL242 | |
| A | GLY456 | |
| A | GLN458 | |
| A | SER461 | |
| B | THR18 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:22334662, ECO:0007744|PDB:3UKP |
| Chain | Residue | Details |
| A | GLY61 | |
| B | GLY61 | |
| C | GLY61 | |
| D | GLY61 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:22334662, ECO:0007744|PDB:3UKF, ECO:0007744|PDB:3UKP, ECO:0007744|PDB:3UKQ |
| Chain | Residue | Details |
| A | GLY62 | |
| B | GLY62 | |
| C | GLY62 | |
| D | GLY62 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 28 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:23036087, ECO:0007744|PDB:5VWT |
| Chain | Residue | Details |
| A | HIS68 | |
| B | SER93 | |
| B | ASN203 | |
| B | TRP315 | |
| B | ARG447 | |
| B | HIS460 | |
| C | HIS68 | |
| C | ARG91 | |
| C | SER93 | |
| C | ASN203 | |
| C | TRP315 | |
| A | ARG91 | |
| C | ARG447 | |
| C | HIS460 | |
| D | HIS68 | |
| D | ARG91 | |
| D | SER93 | |
| D | ASN203 | |
| D | TRP315 | |
| D | ARG447 | |
| D | HIS460 | |
| A | SER93 | |
| A | ASN203 | |
| A | TRP315 | |
| A | ARG447 | |
| A | HIS460 | |
| B | HIS68 | |
| B | ARG91 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 32 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:22294687, ECO:0000269|PubMed:22334662, ECO:0007744|PDB:3UKF, ECO:0007744|PDB:3UKH, ECO:0007744|PDB:3UKP, ECO:0007744|PDB:3UKQ, ECO:0007744|PDB:3UTH |
| Chain | Residue | Details |
| A | TYR104 | |
| B | GLN107 | |
| B | ASN163 | |
| B | TRP167 | |
| B | ARG182 | |
| B | ASN207 | |
| B | TYR419 | |
| B | TYR453 | |
| C | TYR104 | |
| C | GLN107 | |
| C | ASN163 | |
| A | GLN107 | |
| C | TRP167 | |
| C | ARG182 | |
| C | ASN207 | |
| C | TYR419 | |
| C | TYR453 | |
| D | TYR104 | |
| D | GLN107 | |
| D | ASN163 | |
| D | TRP167 | |
| D | ARG182 | |
| A | ASN163 | |
| D | ASN207 | |
| D | TYR419 | |
| D | TYR453 | |
| A | TRP167 | |
| A | ARG182 | |
| A | ASN207 | |
| A | TYR419 | |
| A | TYR453 | |
| B | TYR104 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 8 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:22334662, ECO:0007744|PDB:3UKH, ECO:0007744|PDB:3UKP |
| Chain | Residue | Details |
| A | MET159 | |
| A | TYR162 | |
| B | MET159 | |
| B | TYR162 | |
| C | MET159 | |
| C | TYR162 | |
| D | MET159 | |
| D | TYR162 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:22294687, ECO:0000269|PubMed:22334662, ECO:0007744|PDB:3UKH, ECO:0007744|PDB:3UKQ, ECO:0007744|PDB:3UTH |
| Chain | Residue | Details |
| A | TYR317 | |
| B | TYR317 | |
| C | TYR317 | |
| D | TYR317 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:22294687, ECO:0000269|PubMed:22334662, ECO:0007744|PDB:3UKF, ECO:0007744|PDB:3UKH, ECO:0007744|PDB:3UTH |
| Chain | Residue | Details |
| A | ARG327 | |
| B | ARG327 | |
| C | ARG327 | |
| D | ARG327 |
| site_id | SWS_FT_FI9 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:22334662, ECO:0007744|PDB:3UKH |
| Chain | Residue | Details |
| A | ASN457 | |
| B | ASN457 | |
| C | ASN457 | |
| D | ASN457 |
