3URH
Crystal structure of a dihydrolipoamide dehydrogenase from Sinorhizobium meliloti 1021
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0004148 | molecular_function | dihydrolipoyl dehydrogenase (NADH) activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006103 | biological_process | 2-oxoglutarate metabolic process |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016668 | molecular_function | oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor |
| A | 0050660 | molecular_function | flavin adenine dinucleotide binding |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0004148 | molecular_function | dihydrolipoyl dehydrogenase (NADH) activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006103 | biological_process | 2-oxoglutarate metabolic process |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0016668 | molecular_function | oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor |
| B | 0050660 | molecular_function | flavin adenine dinucleotide binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 35 |
| Details | BINDING SITE FOR RESIDUE FAD A 500 |
| Chain | Residue |
| A | ILE8 |
| A | ARG34 |
| A | GLY39 |
| A | THR40 |
| A | CYS41 |
| A | GLY45 |
| A | CYS46 |
| A | LYS50 |
| A | GLY112 |
| A | THR113 |
| A | GLY114 |
| A | GLY9 |
| A | ALA142 |
| A | THR143 |
| A | GLY144 |
| A | SER145 |
| A | SER165 |
| A | ARG275 |
| A | GLY314 |
| A | ASP315 |
| A | MSE321 |
| A | LEU322 |
| A | SER10 |
| A | ALA323 |
| A | HIS324 |
| A | TYR354 |
| A | HOH476 |
| A | HOH495 |
| B | HIS447 |
| A | GLY11 |
| A | PRO12 |
| A | GLY13 |
| A | VAL31 |
| A | GLU32 |
| A | LYS33 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 501 |
| Chain | Residue |
| A | ARG296 |
| A | ARG318 |
| A | GLY319 |
| A | HOH595 |
| B | LYS286 |
| site_id | AC3 |
| Number of Residues | 34 |
| Details | BINDING SITE FOR RESIDUE FAD B 500 |
| Chain | Residue |
| A | HIS447 |
| B | ILE8 |
| B | GLY9 |
| B | SER10 |
| B | GLY11 |
| B | PRO12 |
| B | GLY13 |
| B | VAL31 |
| B | GLU32 |
| B | LYS33 |
| B | ARG34 |
| B | GLY39 |
| B | THR40 |
| B | CYS41 |
| B | GLY45 |
| B | CYS46 |
| B | LYS50 |
| B | GLY112 |
| B | THR113 |
| B | GLY114 |
| B | ALA142 |
| B | THR143 |
| B | GLY144 |
| B | SER145 |
| B | ILE186 |
| B | ARG275 |
| B | GLY314 |
| B | ASP315 |
| B | MSE321 |
| B | LEU322 |
| B | ALA323 |
| B | HIS324 |
| B | TYR354 |
| B | HOH503 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 B 501 |
| Chain | Residue |
| A | HOH606 |
| B | ASP280 |
| B | GLY281 |
| B | LEU282 |
| B | GLY283 |
| B | HOH563 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO B 502 |
| Chain | Residue |
| B | GLY184 |
| B | VAL185 |
| B | ILE186 |
Functional Information from PROSITE/UniProt
| site_id | PS00076 |
| Number of Residues | 11 |
| Details | PYRIDINE_REDOX_1 Pyridine nucleotide-disulphide oxidoreductases class-I active site. GGtCLnvGCIP |
| Chain | Residue | Details |
| A | GLY38-PRO48 |
