Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004252 | molecular_function | serine-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| B | 0004252 | molecular_function | serine-type endopeptidase activity |
| B | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 A 301 |
| Chain | Residue |
| A | ASN217 |
| A | GLN219 |
| A | HOH483 |
| A | HOH523 |
| A | HOH652 |
| A | HOH693 |
| A | HOH712 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 302 |
| Chain | Residue |
| A | ARG65 |
| A | HOH452 |
| A | ASN36 |
| A | THR62 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 A 303 |
| Chain | Residue |
| A | ARG178 |
| A | HOH403 |
| A | HOH567 |
| A | HOH726 |
| B | THR168 |
| B | ARG178 |
| B | HOH726 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 A 304 |
| Chain | Residue |
| A | HIS57 |
| A | ARG192 |
| A | GLY193 |
| A | SER195 |
| A | HOH418 |
| A | HOH453 |
| A | HOH695 |
| site_id | AC5 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE SO4 B 501 |
| Chain | Residue |
| A | ALA39 |
| A | ARG192 |
| B | GLY120 |
| B | SER120 |
| B | ARG122 |
| B | HOH607 |
| B | HOH608 |
| B | HOH610 |
| B | HOH614 |
| B | HOH646 |
| B | HOH874 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 B 502 |
| Chain | Residue |
| B | ARG120 |
| B | ARG120 |
| B | HOH829 |
| B | HOH829 |
| site_id | AC7 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 B 503 |
| Chain | Residue |
| B | HIS57 |
| B | ARG192 |
| B | GLY193 |
| B | SER195 |
| B | HOH758 |
| B | HOH818 |
| B | HOH855 |
Functional Information from PROSITE/UniProt
| site_id | PS00134 |
| Number of Residues | 6 |
| Details | TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. VTAGHC |
| Chain | Residue | Details |
| A | VAL53-CYS58 | |
| site_id | PS00135 |
| Number of Residues | 12 |
| Details | TRYPSIN_SER Serine proteases, trypsin family, serine active site. CMgrGDSGGSLI |
| Chain | Residue | Details |
| A | CYS189-ILE200 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 6 |
| Details | ACT_SITE: Charge relay system => ECO:0000250 |
| Chain | Residue | Details |
| A | HIS57 | |
| A | ASP102 | |
| A | SER195 | |
| B | HIS57 | |
| B | ASP102 | |
| B | SER195 | |
Catalytic Information from CSA
| site_id | MCSA1 |
| Number of Residues | 5 |
| Details | M-CSA 609 |
| Chain | Residue | Details |
| A | HIS57 | proton acceptor, proton donor |
| A | ASP102 | electrostatic stabiliser |
| A | GLY193 | electrostatic stabiliser |
| A | SER195 | electrostatic stabiliser |
| A | SER214 | electrostatic stabiliser |
| site_id | MCSA2 |
| Number of Residues | 5 |
| Details | M-CSA 609 |
| Chain | Residue | Details |
| B | HIS57 | proton acceptor, proton donor |
| B | ASP102 | electrostatic stabiliser |
| B | GLY193 | electrostatic stabiliser |
| B | SER195 | electrostatic stabiliser |
| B | SER214 | electrostatic stabiliser |
