Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004252 | molecular_function | serine-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE SO4 A 201 |
| Chain | Residue |
| A | ALA1 |
| A | HOH530 |
| A | HOH666 |
| A | ASN2 |
| A | ARG183 |
| A | PRO186 |
| A | HOH350 |
| A | HOH436 |
| A | HOH437 |
| A | HOH485 |
| A | HOH496 |
| site_id | AC2 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE SO4 A 202 |
| Chain | Residue |
| A | HIS36 |
| A | ARG89 |
| A | ARG140 |
| A | GLY141 |
| A | SER143 |
| A | GOL206 |
| A | HOH466 |
| A | HOH467 |
| A | HOH602 |
| A | HOH627 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 A 203 |
| Chain | Residue |
| A | THR39 |
| A | VAL40 |
| A | ARG57 |
| A | HOH417 |
| A | HOH490 |
| A | HOH495 |
| A | HOH634 |
| site_id | AC4 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 A 204 |
| Chain | Residue |
| A | ALA27 |
| A | THR28 |
| A | ALA127 |
| A | ARG129 |
| A | HOH312 |
| A | HOH351 |
| A | HOH370 |
| A | HOH569 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 205 |
| Chain | Residue |
| A | THR120 |
| A | ARG129 |
| A | HOH456 |
| A | HOH557 |
| site_id | AC6 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE GOL A 206 |
| Chain | Residue |
| A | HIS36 |
| A | ARG89 |
| A | TYR123 |
| A | GLU125 |
| A | SER159 |
| A | GLY160 |
| A | SO4202 |
| A | HOH479 |
| A | HOH531 |
Functional Information from PROSITE/UniProt
| site_id | PS00134 |
| Number of Residues | 6 |
| Details | TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. VTAGHC |
| Chain | Residue | Details |
| A | VAL32-CYS37 | |
| site_id | PS00135 |
| Number of Residues | 12 |
| Details | TRYPSIN_SER Serine proteases, trypsin family, serine active site. CMgrGDSGGSWI |
| Chain | Residue | Details |
| A | CYS137-ILE148 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | ACT_SITE: Charge relay system => ECO:0000250 |
| Chain | Residue | Details |
| A | HIS36 | |
| A | ASP63 | |
| A | SER143 | |
Catalytic Information from CSA
| site_id | MCSA1 |
| Number of Residues | 5 |
| Details | M-CSA 609 |
| Chain | Residue | Details |
| A | HIS36 | proton acceptor, proton donor |
| A | ASP63 | electrostatic stabiliser |
| A | GLY141 | electrostatic stabiliser |
| A | SER143 | electrostatic stabiliser |
| A | SER159 | electrostatic stabiliser |
