Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004252 | molecular_function | serine-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE SO4 A 301 |
| Chain | Residue |
| A | HIS57 |
| A | ARG122 |
| A | ARG192 |
| A | GLY193 |
| A | SER195 |
| A | HOH436 |
| A | HOH468 |
| A | HOH561 |
| A | HOH676 |
| site_id | AC2 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE SO4 A 302 |
| Chain | Residue |
| A | ALA15 |
| A | ASN15 |
| A | ARG230 |
| A | GLN232 |
| A | PRO233 |
| A | HOH418 |
| A | HOH437 |
| A | HOH545 |
| A | HOH597 |
| A | HOH753 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL A 303 |
| Chain | Residue |
| A | HIS57 |
| A | ARG122 |
| A | TYR171 |
| A | GLU174 |
| A | SER214 |
| A | GLY215 |
| A | HOH456 |
| A | HOH490 |
Functional Information from PROSITE/UniProt
| site_id | PS00134 |
| Number of Residues | 6 |
| Details | TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. VTAGHC |
| Chain | Residue | Details |
| A | VAL53-CYS58 | |
| site_id | PS00135 |
| Number of Residues | 12 |
| Details | TRYPSIN_SER Serine proteases, trypsin family, serine active site. CMgrGDSGGSWI |
| Chain | Residue | Details |
| A | CYS189-ILE200 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | ACT_SITE: Charge relay system => ECO:0000250 |
| Chain | Residue | Details |
| A | HIS57 | |
| A | ASP102 | |
| A | SER195 | |
Catalytic Information from CSA
| site_id | MCSA1 |
| Number of Residues | 5 |
| Details | M-CSA 609 |
| Chain | Residue | Details |
| A | HIS57 | proton acceptor, proton donor |
| A | ASP102 | electrostatic stabiliser |
| A | GLY193 | electrostatic stabiliser |
| A | SER195 | electrostatic stabiliser |
| A | SER214 | electrostatic stabiliser |
