Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| A | 0016020 | cellular_component | membrane |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 A 501 |
| Chain | Residue |
| A | ARG96 |
| A | ASN98 |
| A | GLU134 |
| A | SER139 |
| A | GLN143 |
| A | HOH630 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 A 502 |
| Chain | Residue |
| A | HIS145 |
| A | PRO147 |
| A | HOH636 |
| A | HOH888 |
| A | HOH949 |
| A | SER22 |
| A | PRO23 |
| A | SER58 |
| site_id | AC3 |
| Number of Residues | 28 |
| Details | BINDING SITE FOR CHAIN B OF 8-MER PEPTIDE INHIBITOR |
| Chain | Residue |
| A | GLY11 |
| A | GLN12 |
| A | ASP32 |
| A | GLY34 |
| A | VAL69 |
| A | PRO70 |
| A | TYR71 |
| A | THR72 |
| A | GLN73 |
| A | PHE108 |
| A | ILE110 |
| A | TRP115 |
| A | ILE126 |
| A | ARG128 |
| A | LEU188 |
| A | TRP197 |
| A | TYR198 |
| A | ASP228 |
| A | GLY230 |
| A | THR231 |
| A | THR232 |
| A | ASN233 |
| A | ARG235 |
| A | HOH688 |
| A | HOH718 |
| A | HOH744 |
| B | HOH101 |
| B | HOH102 |
Functional Information from PROSITE/UniProt
| site_id | PS00141 |
| Number of Residues | 12 |
| Details | ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. ILVDTGSSNFAV |
| Chain | Residue | Details |
| A | ILE29-VAL40 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | ASP32 | |
| A | ASP228 | |
| Chain | Residue | Details |
| A | LYS65 | |
| A | LYS214 | |
| A | LYS218 | |
| A | LYS224 | |
| A | LYS238 | |
| A | LYS239 | |
| A | LYS246 | |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
| Chain | Residue | Details |
| A | ASN92 | |
| A | ASN111 | |
| A | ASN162 | |
| A | ASN293 | |
