Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004190 | molecular_function | aspartic-type endopeptidase activity |
A | 0006508 | biological_process | proteolysis |
A | 0016020 | cellular_component | membrane |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE SO4 A 501 |
Chain | Residue |
A | ARG96 |
A | ASN98 |
A | GLU134 |
A | SER139 |
A | GLN143 |
A | HOH630 |
site_id | AC2 |
Number of Residues | 8 |
Details | BINDING SITE FOR RESIDUE SO4 A 502 |
Chain | Residue |
A | HIS145 |
A | PRO147 |
A | HOH636 |
A | HOH888 |
A | HOH949 |
A | SER22 |
A | PRO23 |
A | SER58 |
site_id | AC3 |
Number of Residues | 28 |
Details | BINDING SITE FOR CHAIN B OF 8-MER PEPTIDE INHIBITOR |
Chain | Residue |
A | GLY11 |
A | GLN12 |
A | ASP32 |
A | GLY34 |
A | VAL69 |
A | PRO70 |
A | TYR71 |
A | THR72 |
A | GLN73 |
A | PHE108 |
A | ILE110 |
A | TRP115 |
A | ILE126 |
A | ARG128 |
A | LEU188 |
A | TRP197 |
A | TYR198 |
A | ASP228 |
A | GLY230 |
A | THR231 |
A | THR232 |
A | ASN233 |
A | ARG235 |
A | HOH688 |
A | HOH718 |
A | HOH744 |
B | HOH101 |
B | HOH102 |
Functional Information from PROSITE/UniProt
site_id | PS00141 |
Number of Residues | 12 |
Details | ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. ILVDTGSSNFAV |
Chain | Residue | Details |
A | ILE29-VAL40 | |
Functional Information from SwissProt/UniProt
Chain | Residue | Details |
A | ASP32 | |
A | ASP228 | |
Chain | Residue | Details |
A | LYS65 | |
A | LYS214 | |
A | LYS218 | |
A | LYS224 | |
A | LYS238 | |
A | LYS239 | |
A | LYS246 | |
site_id | SWS_FT_FI3 |
Number of Residues | 4 |
Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
Chain | Residue | Details |
A | ASN92 | |
A | ASN111 | |
A | ASN162 | |
A | ASN293 | |