3UPP

Structure of penicillin-binding protein A from M. tuberculosis: ceftrixaone acyl-enzyme complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005829	cellular_component	cytosol
A	0005886	cellular_component	plasma membrane
A	0008360	biological_process	regulation of cell shape
A	0008658	molecular_function	penicillin binding
A	0009002	molecular_function	serine-type D-Ala-D-Ala carboxypeptidase activity
A	0009252	biological_process	peptidoglycan biosynthetic process
A	0016787	molecular_function	hydrolase activity
A	0031504	biological_process	peptidoglycan-based cell wall organization
A	0071555	biological_process	cell wall organization
A	0071972	molecular_function	peptidoglycan L,D-transpeptidase activity
B	0005829	cellular_component	cytosol
B	0005886	cellular_component	plasma membrane
B	0008360	biological_process	regulation of cell shape
B	0008658	molecular_function	penicillin binding
B	0009002	molecular_function	serine-type D-Ala-D-Ala carboxypeptidase activity
B	0009252	biological_process	peptidoglycan biosynthetic process
B	0016787	molecular_function	hydrolase activity
B	0031504	biological_process	peptidoglycan-based cell wall organization
B	0071555	biological_process	cell wall organization
B	0071972	molecular_function	peptidoglycan L,D-transpeptidase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	11
Details	BINDING SITE FOR RESIDUE PCZ A 800

site_id	AC2
Number of Residues	12
Details	BINDING SITE FOR RESIDUE PCZ B 800

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	648
Details	Region: {"description":"Transpeptidase"}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	2
Details	Active site: {"description":"Acyl-ester intermediate","evidences":[{"source":"UniProtKB","id":"P0AD65","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details