3UP8
Crystal structure of a putative 2,5-diketo-D-gluconic acid reductase B
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
| A | 0050580 | molecular_function | 2,5-didehydrogluconate reductase activity |
| A | 0051596 | biological_process | methylglyoxal catabolic process |
| A | 1990002 | molecular_function | methylglyoxal reductase (NADPH) (acetol producing) activity |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
| B | 0050580 | molecular_function | 2,5-didehydrogluconate reductase activity |
| B | 0051596 | biological_process | methylglyoxal catabolic process |
| B | 1990002 | molecular_function | methylglyoxal reductase (NADPH) (acetol producing) activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ACT A 276 |
| Chain | Residue |
| A | PHE19 |
| A | TYR47 |
| A | HIS105 |
| A | TYR183 |
| A | HOH287 |
| B | TYR-4 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE ACT B 276 |
| Chain | Residue |
| B | HIS105 |
| B | TYR183 |
| B | HOH285 |
| B | HOH305 |
| A | TYR-4 |
| B | PHE19 |
| B | TYR47 |
Functional Information from PROSITE/UniProt
| site_id | PS00062 |
| Number of Residues | 18 |
| Details | ALDOKETO_REDUCTASE_2 Aldo/keto reductase family signature 2. LnevrnagkVRHIGISNF |
| Chain | Residue | Details |
| A | LEU120-PHE137 |
| site_id | PS00798 |
| Number of Residues | 18 |
| Details | ALDOKETO_REDUCTASE_1 Aldo/keto reductase family signature 1. GFRHVDTAqiygnEaeVG |
| Chain | Residue | Details |
| A | GLY37-GLY54 |
