3ULV

Structure of quaternary complex of human TLR3ecd with three Fabs (Form2)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0002224	biological_process	toll-like receptor signaling pathway
A	0004888	molecular_function	transmembrane signaling receptor activity
A	0006955	biological_process	immune response
A	0016020	cellular_component	membrane

Functional Information from PROSITE/UniProt

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YTCNVDH

Chain	Residue	Details
H	TYR202-HIS208
D	TYR203-HIS209
F	TYR200-HIS206
E	TYR193-HIS199
L	TYR192-HIS198
C	TYR192-HIS198

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:16043704, ECO:0000269|PubMed:19159218, ECO:0000269|PubMed:22579623

Chain	Residue	Details
A	ASN52

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site_id	SWS_FT_FI2
Number of Residues	1
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:19159218

Chain	Residue	Details
A	ASN57

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site_id	SWS_FT_FI3
Number of Residues	2
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:16043704, ECO:0000269|PubMed:22579623

Chain	Residue	Details
A	ASN70
A	ASN265

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site_id	SWS_FT_FI4
Number of Residues	1
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:15961631, ECO:0000269|PubMed:22579623

Chain	Residue	Details
A	ASN124

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site_id	SWS_FT_FI5
Number of Residues	2
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:16043704

Chain	Residue	Details
A	ASN196
A	ASN636

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site_id	SWS_FT_FI6
Number of Residues	1
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:22579623

Chain	Residue	Details
A	ASN247

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site_id	SWS_FT_FI7
Number of Residues	6
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:15961631, ECO:0000269|PubMed:16043704, ECO:0000269|PubMed:22579623

Chain	Residue	Details
A	ASN252
A	ASN275
A	ASN291
A	ASN398
A	ASN413
A	ASN507

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site_id	SWS_FT_FI8
Number of Residues	1
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255

Chain	Residue	Details
A	ASN662

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