Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

3UKL

Crystal structure of UDP-galactopyranose mutase from Aspergillus fumigatus in complex with UDP

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0008767	molecular_function	UDP-galactopyranose mutase activity
A	0016853	molecular_function	isomerase activity
A	0071555	biological_process	cell wall organization
B	0000166	molecular_function	nucleotide binding
B	0008767	molecular_function	UDP-galactopyranose mutase activity
B	0016853	molecular_function	isomerase activity
B	0071555	biological_process	cell wall organization
C	0000166	molecular_function	nucleotide binding
C	0008767	molecular_function	UDP-galactopyranose mutase activity
C	0016853	molecular_function	isomerase activity
C	0071555	biological_process	cell wall organization
D	0000166	molecular_function	nucleotide binding
D	0008767	molecular_function	UDP-galactopyranose mutase activity
D	0016853	molecular_function	isomerase activity
D	0071555	biological_process	cell wall organization
E	0000166	molecular_function	nucleotide binding
E	0008767	molecular_function	UDP-galactopyranose mutase activity
E	0016853	molecular_function	isomerase activity
E	0071555	biological_process	cell wall organization
F	0000166	molecular_function	nucleotide binding
F	0008767	molecular_function	UDP-galactopyranose mutase activity
F	0016853	molecular_function	isomerase activity
F	0071555	biological_process	cell wall organization
G	0000166	molecular_function	nucleotide binding
G	0008767	molecular_function	UDP-galactopyranose mutase activity
G	0016853	molecular_function	isomerase activity
G	0071555	biological_process	cell wall organization
H	0000166	molecular_function	nucleotide binding
H	0008767	molecular_function	UDP-galactopyranose mutase activity
H	0016853	molecular_function	isomerase activity
H	0071555	biological_process	cell wall organization

Functional Information from PDB Data

site_id	AC1
Number of Residues	16
Details	BINDING SITE FOR RESIDUE UDP A 800

Chain	Residue
A	TYR104
A	VAL183
A	TYR317
A	ARG327
A	TYR419
A	TYR453
A	HOH554
A	HOH1052
A	PHE106
A	GLN107
A	PHE142
A	PHE158
A	MET159
A	ASN163
A	TRP167
A	ARG182

site_id	AC2
Number of Residues	30
Details	BINDING SITE FOR RESIDUE FAD A 602

Chain	Residue
A	GLY14
A	GLY16
A	PRO17
A	THR18
A	ASP38
A	SER39
A	GLY45
A	LEU46
A	VAL60
A	GLY62
A	HIS63
A	VAL64
A	GLY240
A	LYS241
A	VAL242
A	MET269
A	THR295
A	GLU373
A	GLY418
A	TYR419
A	GLY446
A	ARG447
A	GLY456
A	ASN457
A	GLN458
A	SER461
A	HOH653
A	HOH798
A	HOH807
A	HOH833

site_id	AC3
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CL A 1

Chain	Residue
A	GLN358

site_id	AC4
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CL A 512

Chain	Residue
A	ALA270

site_id	AC5
Number of Residues	17
Details	BINDING SITE FOR RESIDUE UDP B 800

Chain	Residue
B	VAL95
B	TYR104
B	PHE106
B	GLN107
B	PHE158
B	MET159
B	ASN163
B	TRP167
B	ARG182
B	VAL183
B	TYR317
B	ARG327
B	TYR419
B	TYR453
B	HOH566
B	HOH936
B	HOH1053

site_id	AC6
Number of Residues	29
Details	BINDING SITE FOR RESIDUE FAD B 604

Chain	Residue
B	GLY14
B	GLY16
B	PRO17
B	THR18
B	ASP38
B	SER39
B	GLY45
B	LEU46
B	VAL60
B	GLY62
B	HIS63
B	VAL64
B	GLY240
B	VAL242
B	THR295
B	GLU373
B	GLY418
B	TYR419
B	GLY446
B	ARG447
B	GLY456
B	ASN457
B	GLN458
B	SER461
B	HOH558
B	HOH588
B	HOH605
B	HOH606
B	HOH808

site_id	AC7
Number of Residues	17
Details	BINDING SITE FOR RESIDUE UDP C 800

Chain	Residue
C	MET159
C	ASN163
C	TRP167
C	ARG182
C	VAL183
C	TYR317
C	ARG327
C	TYR419
C	TYR453
C	HOH589
C	HOH969
C	HOH1054
C	VAL95
C	TYR104
C	PHE106
C	GLN107
C	PHE158

site_id	AC8
Number of Residues	25
Details	BINDING SITE FOR RESIDUE FAD C 600

Chain	Residue
C	GLY14
C	GLY16
C	PRO17
C	THR18
C	ASP38
C	SER39
C	GLY45
C	LEU46
C	VAL60
C	HIS63
C	VAL64
C	GLY240
C	VAL242
C	MET269
C	GLU373
C	GLY418
C	GLY446
C	ARG447
C	GLY456
C	ASN457
C	GLN458
C	SER461
C	HOH514
C	HOH519
C	HOH619

site_id	AC9
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CL C 1

Chain	Residue
C	GLN358
C	HOH618

site_id	BC1
Number of Residues	16
Details	BINDING SITE FOR RESIDUE UDP D 800

Chain	Residue
D	VAL95
D	TYR104
D	PHE106
D	GLN107
D	PHE142
D	PHE158
D	MET159
D	ASN163
D	TRP167
D	ARG182
D	VAL183
D	TYR317
D	ARG327
D	TYR419
D	TYR453
D	HOH546

site_id	BC2
Number of Residues	31
Details	BINDING SITE FOR RESIDUE FAD D 601

Chain	Residue
D	GLY14
D	GLY16
D	PRO17
D	THR18
D	ASP38
D	SER39
D	GLY45
D	LEU46
D	ALA47
D	VAL60
D	GLY62
D	HIS63
D	VAL64
D	GLY240
D	LYS241
D	VAL242
D	MET269
D	THR295
D	GLU373
D	GLY418
D	TYR419
D	GLY446
D	ARG447
D	GLY456
D	ASN457
D	GLN458
D	SER461
D	HOH517
D	HOH558
D	HOH585
D	HOH799

site_id	BC3
Number of Residues	15
Details	BINDING SITE FOR RESIDUE UDP E 800

Chain	Residue
E	TYR104
E	PHE106
E	GLN107
E	PHE158
E	MET159
E	ASN163
E	TRP167
E	ARG182
E	VAL183
E	TYR317
E	ARG327
E	TYR419
E	TYR453
E	HOH547
E	HOH576

site_id	BC4
Number of Residues	29
Details	BINDING SITE FOR RESIDUE FAD E 606

Chain	Residue
E	GLY14
E	GLY16
E	PRO17
E	THR18
E	ASP38
E	SER39
E	GLY45
E	LEU46
E	VAL60
E	GLY62
E	HIS63
E	VAL64
E	GLY240
E	VAL242
E	MET269
E	THR295
E	GLU373
E	GLY418
E	TYR419
E	GLY446
E	ARG447
E	GLY456
E	ASN457
E	GLN458
E	SER461
E	HOH517
E	HOH558
E	HOH586
E	HOH809

site_id	BC5
Number of Residues	16
Details	BINDING SITE FOR RESIDUE UDP F 800

Chain	Residue
F	VAL95
F	TYR104
F	PHE106
F	GLN107
F	PHE158
F	MET159
F	ASN163
F	TRP167
F	ARG182
F	VAL183
F	TYR317
F	ARG327
F	TYR419
F	TYR453
F	HOH555
F	HOH564

site_id	BC6
Number of Residues	28
Details	BINDING SITE FOR RESIDUE FAD F 603

Chain	Residue
F	GLY14
F	GLY16
F	PRO17
F	THR18
F	ASP38
F	SER39
F	GLY45
F	LEU46
F	ALA47
F	VAL60
F	GLY62
F	HIS63
F	VAL64
F	GLY240
F	VAL242
F	MET269
F	THR295
F	GLU373
F	GLY418
F	TYR419
F	GLY446
F	ARG447
F	GLY456
F	ASN457
F	GLN458
F	SER461
F	HOH513
F	HOH515

site_id	BC7
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CL F 1

Chain	Residue
F	GLN358

site_id	BC8
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CL F 512

Chain	Residue
F	ALA270

site_id	BC9
Number of Residues	14
Details	BINDING SITE FOR RESIDUE UDP G 800

Chain	Residue
G	TYR104
G	PHE106
G	GLN107
G	PHE158
G	MET159
G	ASN163
G	TRP167
G	ARG182
G	VAL183
G	TYR317
G	ARG327
G	TYR419
G	TYR453
G	HOH1049

site_id	CC1
Number of Residues	29
Details	BINDING SITE FOR RESIDUE FAD G 607

Chain	Residue
G	GLY14
G	GLY16
G	PRO17
G	THR18
G	ASP38
G	SER39
G	GLY45
G	LEU46
G	ALA47
G	VAL60
G	HIS63
G	VAL64
G	GLY240
G	LYS241
G	VAL242
G	MET269
G	THR295
G	GLU373
G	GLY418
G	TYR419
G	GLY446
G	ARG447
G	GLY456
G	ASN457
G	GLN458
G	SER461
G	HOH512
G	HOH554
G	HOH556

site_id	CC2
Number of Residues	15
Details	BINDING SITE FOR RESIDUE UDP H 800

Chain	Residue
H	VAL95
H	TYR104
H	PHE106
H	GLN107
H	PHE158
H	MET159
H	ASN163
H	TRP167
H	ARG182
H	VAL183
H	TYR317
H	ARG327
H	TYR419
H	TYR453
H	HOH875

site_id	CC3
Number of Residues	27
Details	BINDING SITE FOR RESIDUE FAD H 605

Chain	Residue
H	GLY14
H	GLY16
H	PRO17
H	THR18
H	ASP38
H	SER39
H	GLY45
H	LEU46
H	VAL60
H	GLY62
H	HIS63
H	VAL64
H	GLY240
H	VAL242
H	MET269
H	THR295
H	GLU373
H	GLY418
H	TYR419
H	GLY446
H	ARG447
H	GLY456
H	ASN457
H	GLN458
H	SER461
H	HOH806
H	HOH810

site_id	CC4
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CL H 1

Chain	Residue
H	GLN358

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	64
Details	Binding site: {"evidences":[{"source":"PubMed","id":"22294687","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22334662","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3UKA","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3UKH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3UKK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3UKL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3UKP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3UTE","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	8
Details	Binding site: {"evidences":[{"source":"PubMed","id":"22334662","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3UKP","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI3
Number of Residues	8
Details	Binding site: {"evidences":[{"source":"PubMed","id":"22334662","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3UKF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3UKP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3UKQ","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI4
Number of Residues	56
Details	Binding site: {"evidences":[{"source":"PubMed","id":"23036087","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5VWT","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI5
Number of Residues	64
Details	Binding site: {"evidences":[{"source":"PubMed","id":"22294687","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22334662","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3UKF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3UKH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3UKP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3UKQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3UTH","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI6
Number of Residues	16
Details	Binding site: {"evidences":[{"source":"PubMed","id":"22334662","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3UKH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3UKP","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI7
Number of Residues	8
Details	Binding site: {"evidences":[{"source":"PubMed","id":"22294687","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22334662","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3UKH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3UKQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3UTH","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI8
Number of Residues	8
Details	Binding site: {"evidences":[{"source":"PubMed","id":"22294687","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22334662","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3UKF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3UKH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3UTH","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI9
Number of Residues	8
Details	Binding site: {"evidences":[{"source":"PubMed","id":"22334662","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3UKH","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)