3UKL
Crystal structure of UDP-galactopyranose mutase from Aspergillus fumigatus in complex with UDP
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0008767 | molecular_function | UDP-galactopyranose mutase activity |
| A | 0016853 | molecular_function | isomerase activity |
| A | 0071555 | biological_process | cell wall organization |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0008767 | molecular_function | UDP-galactopyranose mutase activity |
| B | 0016853 | molecular_function | isomerase activity |
| B | 0071555 | biological_process | cell wall organization |
| C | 0000166 | molecular_function | nucleotide binding |
| C | 0008767 | molecular_function | UDP-galactopyranose mutase activity |
| C | 0016853 | molecular_function | isomerase activity |
| C | 0071555 | biological_process | cell wall organization |
| D | 0000166 | molecular_function | nucleotide binding |
| D | 0008767 | molecular_function | UDP-galactopyranose mutase activity |
| D | 0016853 | molecular_function | isomerase activity |
| D | 0071555 | biological_process | cell wall organization |
| E | 0000166 | molecular_function | nucleotide binding |
| E | 0008767 | molecular_function | UDP-galactopyranose mutase activity |
| E | 0016853 | molecular_function | isomerase activity |
| E | 0071555 | biological_process | cell wall organization |
| F | 0000166 | molecular_function | nucleotide binding |
| F | 0008767 | molecular_function | UDP-galactopyranose mutase activity |
| F | 0016853 | molecular_function | isomerase activity |
| F | 0071555 | biological_process | cell wall organization |
| G | 0000166 | molecular_function | nucleotide binding |
| G | 0008767 | molecular_function | UDP-galactopyranose mutase activity |
| G | 0016853 | molecular_function | isomerase activity |
| G | 0071555 | biological_process | cell wall organization |
| H | 0000166 | molecular_function | nucleotide binding |
| H | 0008767 | molecular_function | UDP-galactopyranose mutase activity |
| H | 0016853 | molecular_function | isomerase activity |
| H | 0071555 | biological_process | cell wall organization |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE UDP A 800 |
| Chain | Residue |
| A | TYR104 |
| A | VAL183 |
| A | TYR317 |
| A | ARG327 |
| A | TYR419 |
| A | TYR453 |
| A | HOH554 |
| A | HOH1052 |
| A | PHE106 |
| A | GLN107 |
| A | PHE142 |
| A | PHE158 |
| A | MET159 |
| A | ASN163 |
| A | TRP167 |
| A | ARG182 |
| site_id | AC2 |
| Number of Residues | 30 |
| Details | BINDING SITE FOR RESIDUE FAD A 602 |
| Chain | Residue |
| A | GLY14 |
| A | GLY16 |
| A | PRO17 |
| A | THR18 |
| A | ASP38 |
| A | SER39 |
| A | GLY45 |
| A | LEU46 |
| A | VAL60 |
| A | GLY62 |
| A | HIS63 |
| A | VAL64 |
| A | GLY240 |
| A | LYS241 |
| A | VAL242 |
| A | MET269 |
| A | THR295 |
| A | GLU373 |
| A | GLY418 |
| A | TYR419 |
| A | GLY446 |
| A | ARG447 |
| A | GLY456 |
| A | ASN457 |
| A | GLN458 |
| A | SER461 |
| A | HOH653 |
| A | HOH798 |
| A | HOH807 |
| A | HOH833 |
| site_id | AC3 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CL A 1 |
| Chain | Residue |
| A | GLN358 |
| site_id | AC4 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CL A 512 |
| Chain | Residue |
| A | ALA270 |
| site_id | AC5 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE UDP B 800 |
| Chain | Residue |
| B | VAL95 |
| B | TYR104 |
| B | PHE106 |
| B | GLN107 |
| B | PHE158 |
| B | MET159 |
| B | ASN163 |
| B | TRP167 |
| B | ARG182 |
| B | VAL183 |
| B | TYR317 |
| B | ARG327 |
| B | TYR419 |
| B | TYR453 |
| B | HOH566 |
| B | HOH936 |
| B | HOH1053 |
| site_id | AC6 |
| Number of Residues | 29 |
| Details | BINDING SITE FOR RESIDUE FAD B 604 |
| Chain | Residue |
| B | GLY14 |
| B | GLY16 |
| B | PRO17 |
| B | THR18 |
| B | ASP38 |
| B | SER39 |
| B | GLY45 |
| B | LEU46 |
| B | VAL60 |
| B | GLY62 |
| B | HIS63 |
| B | VAL64 |
| B | GLY240 |
| B | VAL242 |
| B | THR295 |
| B | GLU373 |
| B | GLY418 |
| B | TYR419 |
| B | GLY446 |
| B | ARG447 |
| B | GLY456 |
| B | ASN457 |
| B | GLN458 |
| B | SER461 |
| B | HOH558 |
| B | HOH588 |
| B | HOH605 |
| B | HOH606 |
| B | HOH808 |
| site_id | AC7 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE UDP C 800 |
| Chain | Residue |
| C | MET159 |
| C | ASN163 |
| C | TRP167 |
| C | ARG182 |
| C | VAL183 |
| C | TYR317 |
| C | ARG327 |
| C | TYR419 |
| C | TYR453 |
| C | HOH589 |
| C | HOH969 |
| C | HOH1054 |
| C | VAL95 |
| C | TYR104 |
| C | PHE106 |
| C | GLN107 |
| C | PHE158 |
| site_id | AC8 |
| Number of Residues | 25 |
| Details | BINDING SITE FOR RESIDUE FAD C 600 |
| Chain | Residue |
| C | GLY14 |
| C | GLY16 |
| C | PRO17 |
| C | THR18 |
| C | ASP38 |
| C | SER39 |
| C | GLY45 |
| C | LEU46 |
| C | VAL60 |
| C | HIS63 |
| C | VAL64 |
| C | GLY240 |
| C | VAL242 |
| C | MET269 |
| C | GLU373 |
| C | GLY418 |
| C | GLY446 |
| C | ARG447 |
| C | GLY456 |
| C | ASN457 |
| C | GLN458 |
| C | SER461 |
| C | HOH514 |
| C | HOH519 |
| C | HOH619 |
| site_id | AC9 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL C 1 |
| Chain | Residue |
| C | GLN358 |
| C | HOH618 |
| site_id | BC1 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE UDP D 800 |
| Chain | Residue |
| D | VAL95 |
| D | TYR104 |
| D | PHE106 |
| D | GLN107 |
| D | PHE142 |
| D | PHE158 |
| D | MET159 |
| D | ASN163 |
| D | TRP167 |
| D | ARG182 |
| D | VAL183 |
| D | TYR317 |
| D | ARG327 |
| D | TYR419 |
| D | TYR453 |
| D | HOH546 |
| site_id | BC2 |
| Number of Residues | 31 |
| Details | BINDING SITE FOR RESIDUE FAD D 601 |
| Chain | Residue |
| D | GLY14 |
| D | GLY16 |
| D | PRO17 |
| D | THR18 |
| D | ASP38 |
| D | SER39 |
| D | GLY45 |
| D | LEU46 |
| D | ALA47 |
| D | VAL60 |
| D | GLY62 |
| D | HIS63 |
| D | VAL64 |
| D | GLY240 |
| D | LYS241 |
| D | VAL242 |
| D | MET269 |
| D | THR295 |
| D | GLU373 |
| D | GLY418 |
| D | TYR419 |
| D | GLY446 |
| D | ARG447 |
| D | GLY456 |
| D | ASN457 |
| D | GLN458 |
| D | SER461 |
| D | HOH517 |
| D | HOH558 |
| D | HOH585 |
| D | HOH799 |
| site_id | BC3 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE UDP E 800 |
| Chain | Residue |
| E | TYR104 |
| E | PHE106 |
| E | GLN107 |
| E | PHE158 |
| E | MET159 |
| E | ASN163 |
| E | TRP167 |
| E | ARG182 |
| E | VAL183 |
| E | TYR317 |
| E | ARG327 |
| E | TYR419 |
| E | TYR453 |
| E | HOH547 |
| E | HOH576 |
| site_id | BC4 |
| Number of Residues | 29 |
| Details | BINDING SITE FOR RESIDUE FAD E 606 |
| Chain | Residue |
| E | GLY14 |
| E | GLY16 |
| E | PRO17 |
| E | THR18 |
| E | ASP38 |
| E | SER39 |
| E | GLY45 |
| E | LEU46 |
| E | VAL60 |
| E | GLY62 |
| E | HIS63 |
| E | VAL64 |
| E | GLY240 |
| E | VAL242 |
| E | MET269 |
| E | THR295 |
| E | GLU373 |
| E | GLY418 |
| E | TYR419 |
| E | GLY446 |
| E | ARG447 |
| E | GLY456 |
| E | ASN457 |
| E | GLN458 |
| E | SER461 |
| E | HOH517 |
| E | HOH558 |
| E | HOH586 |
| E | HOH809 |
| site_id | BC5 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE UDP F 800 |
| Chain | Residue |
| F | VAL95 |
| F | TYR104 |
| F | PHE106 |
| F | GLN107 |
| F | PHE158 |
| F | MET159 |
| F | ASN163 |
| F | TRP167 |
| F | ARG182 |
| F | VAL183 |
| F | TYR317 |
| F | ARG327 |
| F | TYR419 |
| F | TYR453 |
| F | HOH555 |
| F | HOH564 |
| site_id | BC6 |
| Number of Residues | 28 |
| Details | BINDING SITE FOR RESIDUE FAD F 603 |
| Chain | Residue |
| F | GLY14 |
| F | GLY16 |
| F | PRO17 |
| F | THR18 |
| F | ASP38 |
| F | SER39 |
| F | GLY45 |
| F | LEU46 |
| F | ALA47 |
| F | VAL60 |
| F | GLY62 |
| F | HIS63 |
| F | VAL64 |
| F | GLY240 |
| F | VAL242 |
| F | MET269 |
| F | THR295 |
| F | GLU373 |
| F | GLY418 |
| F | TYR419 |
| F | GLY446 |
| F | ARG447 |
| F | GLY456 |
| F | ASN457 |
| F | GLN458 |
| F | SER461 |
| F | HOH513 |
| F | HOH515 |
| site_id | BC7 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CL F 1 |
| Chain | Residue |
| F | GLN358 |
| site_id | BC8 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CL F 512 |
| Chain | Residue |
| F | ALA270 |
| site_id | BC9 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE UDP G 800 |
| Chain | Residue |
| G | TYR104 |
| G | PHE106 |
| G | GLN107 |
| G | PHE158 |
| G | MET159 |
| G | ASN163 |
| G | TRP167 |
| G | ARG182 |
| G | VAL183 |
| G | TYR317 |
| G | ARG327 |
| G | TYR419 |
| G | TYR453 |
| G | HOH1049 |
| site_id | CC1 |
| Number of Residues | 29 |
| Details | BINDING SITE FOR RESIDUE FAD G 607 |
| Chain | Residue |
| G | GLY14 |
| G | GLY16 |
| G | PRO17 |
| G | THR18 |
| G | ASP38 |
| G | SER39 |
| G | GLY45 |
| G | LEU46 |
| G | ALA47 |
| G | VAL60 |
| G | HIS63 |
| G | VAL64 |
| G | GLY240 |
| G | LYS241 |
| G | VAL242 |
| G | MET269 |
| G | THR295 |
| G | GLU373 |
| G | GLY418 |
| G | TYR419 |
| G | GLY446 |
| G | ARG447 |
| G | GLY456 |
| G | ASN457 |
| G | GLN458 |
| G | SER461 |
| G | HOH512 |
| G | HOH554 |
| G | HOH556 |
| site_id | CC2 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE UDP H 800 |
| Chain | Residue |
| H | VAL95 |
| H | TYR104 |
| H | PHE106 |
| H | GLN107 |
| H | PHE158 |
| H | MET159 |
| H | ASN163 |
| H | TRP167 |
| H | ARG182 |
| H | VAL183 |
| H | TYR317 |
| H | ARG327 |
| H | TYR419 |
| H | TYR453 |
| H | HOH875 |
| site_id | CC3 |
| Number of Residues | 27 |
| Details | BINDING SITE FOR RESIDUE FAD H 605 |
| Chain | Residue |
| H | GLY14 |
| H | GLY16 |
| H | PRO17 |
| H | THR18 |
| H | ASP38 |
| H | SER39 |
| H | GLY45 |
| H | LEU46 |
| H | VAL60 |
| H | GLY62 |
| H | HIS63 |
| H | VAL64 |
| H | GLY240 |
| H | VAL242 |
| H | MET269 |
| H | THR295 |
| H | GLU373 |
| H | GLY418 |
| H | TYR419 |
| H | GLY446 |
| H | ARG447 |
| H | GLY456 |
| H | ASN457 |
| H | GLN458 |
| H | SER461 |
| H | HOH806 |
| H | HOH810 |
| site_id | CC4 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CL H 1 |
| Chain | Residue |
| H | GLN358 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 64 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:22294687, ECO:0000269|PubMed:22334662, ECO:0007744|PDB:3UKA, ECO:0007744|PDB:3UKH, ECO:0007744|PDB:3UKK, ECO:0007744|PDB:3UKL, ECO:0007744|PDB:3UKP, ECO:0007744|PDB:3UTE |
| Chain | Residue | Details |
| A | THR18 | |
| B | ASP38 | |
| B | LEU46 | |
| B | HIS63 | |
| B | VAL242 | |
| B | GLY456 | |
| B | GLN458 | |
| B | SER461 | |
| C | THR18 | |
| C | ASP38 | |
| C | LEU46 | |
| A | ASP38 | |
| C | HIS63 | |
| C | VAL242 | |
| C | GLY456 | |
| C | GLN458 | |
| C | SER461 | |
| D | THR18 | |
| D | ASP38 | |
| D | LEU46 | |
| D | HIS63 | |
| D | VAL242 | |
| A | LEU46 | |
| D | GLY456 | |
| D | GLN458 | |
| D | SER461 | |
| E | THR18 | |
| E | ASP38 | |
| E | LEU46 | |
| E | HIS63 | |
| E | VAL242 | |
| E | GLY456 | |
| E | GLN458 | |
| A | HIS63 | |
| E | SER461 | |
| F | THR18 | |
| F | ASP38 | |
| F | LEU46 | |
| F | HIS63 | |
| F | VAL242 | |
| F | GLY456 | |
| F | GLN458 | |
| F | SER461 | |
| G | THR18 | |
| A | VAL242 | |
| G | ASP38 | |
| G | LEU46 | |
| G | HIS63 | |
| G | VAL242 | |
| G | GLY456 | |
| G | GLN458 | |
| G | SER461 | |
| H | THR18 | |
| H | ASP38 | |
| H | LEU46 | |
| A | GLY456 | |
| H | HIS63 | |
| H | VAL242 | |
| H | GLY456 | |
| H | GLN458 | |
| H | SER461 | |
| A | GLN458 | |
| A | SER461 | |
| B | THR18 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 8 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:22334662, ECO:0007744|PDB:3UKP |
| Chain | Residue | Details |
| A | GLY61 | |
| B | GLY61 | |
| C | GLY61 | |
| D | GLY61 | |
| E | GLY61 | |
| F | GLY61 | |
| G | GLY61 | |
| H | GLY61 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 8 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:22334662, ECO:0007744|PDB:3UKF, ECO:0007744|PDB:3UKP, ECO:0007744|PDB:3UKQ |
| Chain | Residue | Details |
| A | GLY62 | |
| B | GLY62 | |
| C | GLY62 | |
| D | GLY62 | |
| E | GLY62 | |
| F | GLY62 | |
| G | GLY62 | |
| H | GLY62 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 56 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:23036087, ECO:0007744|PDB:5VWT |
| Chain | Residue | Details |
| A | HIS68 | |
| B | SER93 | |
| B | ASN203 | |
| B | TRP315 | |
| B | ARG447 | |
| B | HIS460 | |
| C | HIS68 | |
| C | ARG91 | |
| C | SER93 | |
| C | ASN203 | |
| C | TRP315 | |
| A | ARG91 | |
| C | ARG447 | |
| C | HIS460 | |
| D | HIS68 | |
| D | ARG91 | |
| D | SER93 | |
| D | ASN203 | |
| D | TRP315 | |
| D | ARG447 | |
| D | HIS460 | |
| E | HIS68 | |
| A | SER93 | |
| E | ARG91 | |
| E | SER93 | |
| E | ASN203 | |
| E | TRP315 | |
| E | ARG447 | |
| E | HIS460 | |
| F | HIS68 | |
| F | ARG91 | |
| F | SER93 | |
| F | ASN203 | |
| A | ASN203 | |
| F | TRP315 | |
| F | ARG447 | |
| F | HIS460 | |
| G | HIS68 | |
| G | ARG91 | |
| G | SER93 | |
| G | ASN203 | |
| G | TRP315 | |
| G | ARG447 | |
| G | HIS460 | |
| A | TRP315 | |
| H | HIS68 | |
| H | ARG91 | |
| H | SER93 | |
| H | ASN203 | |
| H | TRP315 | |
| H | ARG447 | |
| H | HIS460 | |
| A | ARG447 | |
| A | HIS460 | |
| B | HIS68 | |
| B | ARG91 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 64 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:22294687, ECO:0000269|PubMed:22334662, ECO:0007744|PDB:3UKF, ECO:0007744|PDB:3UKH, ECO:0007744|PDB:3UKP, ECO:0007744|PDB:3UKQ, ECO:0007744|PDB:3UTH |
| Chain | Residue | Details |
| A | TYR104 | |
| B | GLN107 | |
| B | ASN163 | |
| B | TRP167 | |
| B | ARG182 | |
| B | ASN207 | |
| B | TYR419 | |
| B | TYR453 | |
| C | TYR104 | |
| C | GLN107 | |
| C | ASN163 | |
| A | GLN107 | |
| C | TRP167 | |
| C | ARG182 | |
| C | ASN207 | |
| C | TYR419 | |
| C | TYR453 | |
| D | TYR104 | |
| D | GLN107 | |
| D | ASN163 | |
| D | TRP167 | |
| D | ARG182 | |
| A | ASN163 | |
| D | ASN207 | |
| D | TYR419 | |
| D | TYR453 | |
| E | TYR104 | |
| E | GLN107 | |
| E | ASN163 | |
| E | TRP167 | |
| E | ARG182 | |
| E | ASN207 | |
| E | TYR419 | |
| A | TRP167 | |
| E | TYR453 | |
| F | TYR104 | |
| F | GLN107 | |
| F | ASN163 | |
| F | TRP167 | |
| F | ARG182 | |
| F | ASN207 | |
| F | TYR419 | |
| F | TYR453 | |
| G | TYR104 | |
| A | ARG182 | |
| G | GLN107 | |
| G | ASN163 | |
| G | TRP167 | |
| G | ARG182 | |
| G | ASN207 | |
| G | TYR419 | |
| G | TYR453 | |
| H | TYR104 | |
| H | GLN107 | |
| H | ASN163 | |
| A | ASN207 | |
| H | TRP167 | |
| H | ARG182 | |
| H | ASN207 | |
| H | TYR419 | |
| H | TYR453 | |
| A | TYR419 | |
| A | TYR453 | |
| B | TYR104 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 16 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:22334662, ECO:0007744|PDB:3UKH, ECO:0007744|PDB:3UKP |
| Chain | Residue | Details |
| A | MET159 | |
| E | TYR162 | |
| F | MET159 | |
| F | TYR162 | |
| G | MET159 | |
| G | TYR162 | |
| H | MET159 | |
| H | TYR162 | |
| A | TYR162 | |
| B | MET159 | |
| B | TYR162 | |
| C | MET159 | |
| C | TYR162 | |
| D | MET159 | |
| D | TYR162 | |
| E | MET159 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 8 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:22294687, ECO:0000269|PubMed:22334662, ECO:0007744|PDB:3UKH, ECO:0007744|PDB:3UKQ, ECO:0007744|PDB:3UTH |
| Chain | Residue | Details |
| A | TYR317 | |
| B | TYR317 | |
| C | TYR317 | |
| D | TYR317 | |
| E | TYR317 | |
| F | TYR317 | |
| G | TYR317 | |
| H | TYR317 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 8 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:22294687, ECO:0000269|PubMed:22334662, ECO:0007744|PDB:3UKF, ECO:0007744|PDB:3UKH, ECO:0007744|PDB:3UTH |
| Chain | Residue | Details |
| A | ARG327 | |
| B | ARG327 | |
| C | ARG327 | |
| D | ARG327 | |
| E | ARG327 | |
| F | ARG327 | |
| G | ARG327 | |
| H | ARG327 |
| site_id | SWS_FT_FI9 |
| Number of Residues | 8 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:22334662, ECO:0007744|PDB:3UKH |
| Chain | Residue | Details |
| A | ASN457 | |
| B | ASN457 | |
| C | ASN457 | |
| D | ASN457 | |
| E | ASN457 | |
| F | ASN457 | |
| G | ASN457 | |
| H | ASN457 |
