3UJJ

Crystal structure of anti-HIV-1 V3 Fab 4025 in complex with Con A peptide

Functional Information from GO Data

Chain	GOid	namespace	contents
P	0019031	cellular_component	viral envelope

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE GOL L 212

Chain	Residue
L	TYR2
L	ASN92
L	SER93
L	GLY94
L	HOH427

---

site_id	AC2
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL L 213

Chain	Residue
L	HOH302
L	HOH364
L	HOH397
L	GLN37
L	VAL45
L	PRO59
L	HOH271

---

site_id	AC3
Number of Residues	8
Details	BINDING SITE FOR RESIDUE GOL L 214

Chain	Residue
H	ALA100
L	TYR49
L	ARG54
L	PRO55
L	SER56
L	HOH252
L	HOH333
L	HOH350

---

site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE GOL L 215

Chain	Residue
L	THR205
L	ACT228
L	HOH386
P	THR303

---

site_id	AC5
Number of Residues	8
Details	BINDING SITE FOR RESIDUE GOL L 216

Chain	Residue
H	TYR91
L	GLN38
L	LYS39
L	GLY41
L	GLN42
L	HOH308
L	HOH327
L	HOH349

---

site_id	AC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE GOL L 217

Chain	Residue
H	HOH339
L	SER121
L	SER122
L	HOH372

---

site_id	AC7
Number of Residues	8
Details	BINDING SITE FOR RESIDUE GOL L 218

Chain	Residue
L	SER52
L	LYS53
L	ARG54
L	SO4224
L	SO4225
L	HOH304
L	HOH435
L	HOH468

---

site_id	AC8
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL L 219

Chain	Residue
H	HOH307
H	HOH325
L	GLN42
L	ALA43
L	VAL45
L	HOH283
L	HOH417

---

site_id	AC9
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 L 220

Chain	Residue
H	HIS164
L	GLN167
L	SER168
L	HOH341
L	HOH464

---

site_id	BC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 L 221

Chain	Residue
L	PRO59
L	ARG61
L	GLN79
L	ASP81
L	HOH271

---

site_id	BC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 L 222

Chain	Residue
L	SER40
L	GLU83
L	LYS103
L	TYR172
L	HOH359

---

site_id	BC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 L 223

Chain	Residue
L	PRO154
L	VAL155
L	LYS156
L	ALA157

---

site_id	BC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 L 224

Chain	Residue
L	ARG54
L	SER63
L	GOL218
L	HOH249
L	HOH276

---

site_id	BC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE SO4 L 225

Chain	Residue
L	LYS53
L	LYS186
L	ARG189
L	GOL218
L	HOH435
L	HOH468

---

site_id	BC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE ACT L 226

Chain	Residue
L	THR18
L	ARG20
L	HOH434

---

site_id	BC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ACT L 227

Chain	Residue
L	ASN112
L	THR114
L	VAL115
L	LYS204

---

site_id	BC8
Number of Residues	7
Details	BINDING SITE FOR RESIDUE ACT L 228

Chain	Residue
L	GLU198
L	GLY199
L	GLU203
L	THR205
L	GOL215
L	HOH474
P	ACT2

---

site_id	BC9
Number of Residues	9
Details	BINDING SITE FOR RESIDUE GOL H 220

Chain	Residue
H	HOH372
H	HOH412
L	LEU117
L	PHE118
L	PRO119
H	ALA125
H	SER127
H	ALA137
H	LYS214

---

site_id	CC1
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL H 221

Chain	Residue
H	SER55
H	ASP56
H	THR57
H	HOH247
L	THR5
L	GLN6
L	THR100

---

site_id	CC2
Number of Residues	8
Details	BINDING SITE FOR RESIDUE GOL H 222

Chain	Residue
H	SER130
H	THR131
H	SER132
H	GLY133
H	SER186
H	SER187
H	ACT233
H	HOH426

---

site_id	CC3
Number of Residues	8
Details	BINDING SITE FOR RESIDUE GOL H 223

Chain	Residue
H	GLY65
H	GLN66
H	GLY67
H	TRP82
H	SER82
H	SER82
H	HOH368
H	HOH443

---

site_id	CC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL H 224

Chain	Residue
H	MET40
H	LYS43
H	GLY44
H	GLU46
H	HOH239
L	HOH438

---

site_id	CC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL H 225

Chain	Residue
H	LYS117
H	SER120
H	ASP144
H	HOH405
L	LYS129
L	HOH313

---

site_id	CC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE GOL H 226

Chain	Residue
H	TYR27
H	SER28
H	PHE29
H	SER30
H	HOH323

---

site_id	CC7
Number of Residues	11
Details	BINDING SITE FOR RESIDUE GOL H 227

Chain	Residue
H	GLY118
H	SER120
H	VAL121
H	PHE122
H	THR205
H	VAL207
H	LYS209
H	HOH248
H	HOH248
H	HOH329
L	GLU123

---

site_id	CC8
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL H 228

Chain	Residue
H	LYS83
H	ALA84
H	SER85
H	HOH343
H	HOH373
H	HOH479

---

site_id	CC9
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL H 229

Chain	Residue
H	PRO41
H	LEU170
H	TYR176
H	HOH319
H	HOH370
H	HOH480

---

site_id	DC1
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL H 230

Chain	Residue
H	ARG38
H	SER62
H	PHE63
H	GLN66
H	LYS83
H	HOH299
H	HOH333

---

site_id	DC2
Number of Residues	9
Details	BINDING SITE FOR RESIDUE SO4 H 231

Chain	Residue
H	GLN171
H	SER172
H	HOH237
H	HOH298
H	HOH300
H	HOH303
L	GLY158
L	GLU160
L	SER179

---

site_id	DC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 H 232

Chain	Residue
H	TYR27
H	SER28
H	TYR32
H	HOH377
P	ARG304

---

site_id	DC4
Number of Residues	7
Details	BINDING SITE FOR RESIDUE ACT H 233

Chain	Residue
H	SER127
H	SER128
H	LYS129
H	SER186
H	LEU189
H	THR219
H	GOL222

---

site_id	DC5
Number of Residues	2
Details	BINDING SITE FOR RESIDUE ACT H 234

Chain	Residue
H	SER30
H	LYS73

---

site_id	DC6
Number of Residues	2
Details	BINDING SITE FOR RESIDUE ACT H 235

Chain	Residue
H	GLY26
H	HOH421

---

site_id	DC7
Number of Residues	3
Details	BINDING SITE FOR RESIDUE ACT P 2

Chain	Residue
L	ACT228
P	THR303
P	HOH414

---

Functional Information from PROSITE/UniProt

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YICNVNH

Chain	Residue	Details
H	TYR194-HIS200
L	TYR191-HIS197

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