3UJD

Phosphoethanolamine methyltransferase mutant (Y19F) from Plasmodium falciparum in complex with phosphocholine

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000139	cellular_component	Golgi membrane
A	0000234	molecular_function	phosphoethanolamine N-methyltransferase activity
A	0005737	cellular_component	cytoplasm
A	0005794	cellular_component	Golgi apparatus
A	0006656	biological_process	phosphatidylcholine biosynthetic process
A	0008168	molecular_function	methyltransferase activity
A	0008654	biological_process	phospholipid biosynthetic process
A	0016020	cellular_component	membrane
A	0032259	biological_process	methylation
A	0052667	molecular_function	phosphomethylethanolamine N-methyltransferase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	10
Details	BINDING SITE FOR RESIDUE PC A 301

Chain	Residue
A	GLN18
A	HOH388
A	TYR27
A	ILE36
A	ASP128
A	TYR160
A	TYR175
A	ARG179
A	TYR181
A	LYS247

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	ACT_SITE: ACT_SITE => ECO:0000269|PubMed:22117061

Chain	Residue	Details
A	PHE19
A	HIS132

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site_id	SWS_FT_FI2
Number of Residues	7
Details	BINDING: BINDING => ECO:0000269|PubMed:22117061, ECO:0000269|PubMed:25288796, ECO:0007744|PDB:3UJ9, ECO:0007744|PDB:3UJA, ECO:0007744|PDB:3UJB, ECO:0007744|PDB:3UJC, ECO:0007744|PDB:3UJD, ECO:0007744|PDB:4R6W

Chain	Residue	Details
A	GLN18
A	TYR27
A	TYR160
A	TYR175
A	ARG179
A	TYR181
A	LYS247

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site_id	SWS_FT_FI3
Number of Residues	8
Details	BINDING: BINDING => ECO:0000269|PubMed:22117061, ECO:0000269|PubMed:22771008, ECO:0000269|PubMed:25288796, ECO:0007744|PDB:3UJ6, ECO:0007744|PDB:3UJ7, ECO:0007744|PDB:3UJB, ECO:0007744|PDB:4FGZ, ECO:0007744|PDB:4R6W, ECO:0007744|PDB:4R6X

Chain	Residue	Details
A	ILE36
A	SER37
A	GLY63
A	ASP85
A	ILE86
A	ASP110
A	ILE111
A	ARG127

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