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3UHM

UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase in complex with inhibitor

Functional Information from GO Data
ChainGOidnamespacecontents
A0006796biological_processphosphate-containing compound metabolic process
A0009245biological_processlipid A biosynthetic process
A0016020cellular_componentmembrane
A0016787molecular_functionhydrolase activity
A0019637biological_processorganophosphate metabolic process
A0046872molecular_functionmetal ion binding
A0103117molecular_functionUDP-3-O-acyl-N-acetylglucosamine deacetylase activity
A1901135biological_processcarbohydrate derivative metabolic process
Functional Information from PDB Data
site_idAC1
Number of Residues4
DetailsBINDING SITE FOR RESIDUE ZN A 300
ChainResidue
AHIS78
AHIS237
AASP241
ARFN303

site_idAC2
Number of Residues16
DetailsBINDING SITE FOR RESIDUE RFN A 303
ChainResidue
ATHR190
APHE191
AGLY192
ALEU200
AHIS237
ALYS238
AASP241
AHIS264
AZN300
AEDO302
AHOH375
ALEU18
AHIS19
AMET62
AGLU77
AHIS78

site_idAC3
Number of Residues3
DetailsBINDING SITE FOR RESIDUE GAI A 301
ChainResidue
ALEU205
AALA206
AHOH470

site_idAC4
Number of Residues6
DetailsBINDING SITE FOR RESIDUE EDO A 302
ChainResidue
AMET62
APHE191
AGLY192
APHE193
AASP196
ARFN303

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues1
DetailsACT_SITE: Proton donor => ECO:0000255|HAMAP-Rule:MF_00388
ChainResidueDetails
AHIS264

site_idSWS_FT_FI2
Number of Residues3
DetailsBINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00388
ChainResidueDetails
AHIS78
AHIS237
AASP241

227344

PDB entries from 2024-11-13

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